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The protein encoded by 104116 is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Zusätzlich bieten wir Ihnen Zinc Finger Protein 346 Antikörper (97) und und viele weitere Produktgruppen zu diesem Protein an.
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JAZ directly binds E2F1 (zeige E2F1 Proteine) in vitro in a dsRNA-independent manner, and JAZ's dsRNA binding ZF domains, which are necessary for localizing JAZ to the nucleus, are required for repression of transcriptional activity in vivo.
JAZ is exported by exportin-5 (zeige XPO5 Proteine) but translocates back into nuclei by a facilitated diffusion mechanism
JAZ is a novel negative regulator of cell growth by positively regulating p53 (zeige TP53 Proteine).
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.
zinc finger protein 346
, Just another zinc finger protein
, Protein jaz
, double-stranded RNA-binding zinc finger protein JAZ
, just another zinc finger protein
, Double stranded RNA-binding protein ZFa