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May be involved in transcriptional regulation. Zusätzlich bieten wir Ihnen Zinc Finger Protein 131 Antikörper (83) und viele weitere Produktgruppen zu diesem Protein an.
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identify a novel substoichiometric interactor of the complex, transcription factor ZNF131, which recruits EMSY (zeige C11orf30 Proteine) to a large number of active, H3K4me3 marked promoters.
UHRF2 (zeige UHRF2 Proteine), a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier (zeige SUMO1 Proteine) E3 ligase for zinc finger protein 131
these data suggest that ZNF131 inhibits estrogen signaling by acting as an ERalpha (zeige ESR1 Proteine)-co-repressor.
SUMOylation is a novel regulator of ZNF131 action in estrogen signaling and breast cancer cell proliferation.
The mechanism of Znf131 nuclear localization, is reported.
Interaction between ZNF131 and ERalpha (zeige ESR1 Proteine) interrupts or prevents ERalpha (zeige ESR1 Proteine) binding to the estrogen response element. ZNF131 also suppresses the expression of TFF1 (zeige TFF1 Proteine).
We also demonstrate that Kaiso (zeige ZBTB33 Proteine) inhibits Znf131 expression, raising the possibility that Kaiso (zeige ZBTB33 Proteine) and Znf131 act to fine-tune target gene expression. Together, our findings implicate Znf131 as a co-regulator of Kaiso (zeige ZBTB33 Proteine)-mediated biological processes.
Znf131 is critical for T cell development during double-negative to double-positive stage, with which significant cell expansion triggered by the pre-TCR signal is coupled.
Znf131 is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner Kaiso (zeige ZBTB33 Proteine).
Results suggest that Znf131/ZNF131 plays a role during development and organogenesis as well as in the function of the adult central nervous system.
May be involved in transcriptional regulation. Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity).
zinc finger and BTB domain containing 35
, zinc finger protein 131 (clone pHZ-10)
, putative transcription factor ZNF131