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Pre-mRNA splicing is catalyzed by the spliceosome. Zusätzlich bieten wir Ihnen ZCRB1 Antikörper (38) und und viele weitere Produktgruppen zu diesem Protein an.
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Using small interfering RNA against MADP1, defective viral RNA synthesis was observed in the knockdown cells, therefore indicating the importance of the protein in coronaviral RNA synthesis.
The 5'-flanking region contains an enhancer core motif and binding sites for AP-1, AP-2, and LF-A1. ZCRB1 is characterized by an RNA-binding motif and a CCHC zinc finger motif.
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
zinc finger CCHC-type and RNA binding motif 1
, zinc finger CCHC-type and RNA-binding motif-containing protein 1
, U11/U12 small nuclear ribonucleoprotein 31 kDa protein
, U11/U12 snRNP 31 kDa protein
, U11/U12 snRNP 31K