XiAP Associated Factor 1 Proteine (XAF1)

XAF1 encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. Zusätzlich bieten wir Ihnen XAF1 Antikörper (92) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
XAF1 54739 Q6GPH4
Maus XAF1 XAF1 327959 Q5NBU8
Ratte XAF1 XAF1 679600  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage

XAF1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,

Weitere Proteine zu XiAP Associated Factor 1 (XAF1) Interaktionspartnern

Human XiAP Associated Factor 1 (XAF1) Interaktionspartner

  1. XAF1 expression was markedly altered in non-small cell lung cancer tumor samples when compared to that found in normal lung tissues.

  2. XAF1 expression was associated with VM in ovarian cancer, suggesting a potential role of XAF1 in the formation of VM in EOC.

  3. XAF1 may be a candidate tumor suppressor in neuroblastoma (zeige ARHGEF16 Proteine)

  4. Dysfunction of XAF1 is frequent and is regulated through XAF1 promoter hypermethylation in gastric cancer. Circulating methylated XAF1 DNA was associated with tumor burden and malignant progression, which may be a valuable biomarker for diagnosis of gastric cancer, predicting patients' prognosis and monitoring tumor recurrence after surgery treatment.

  5. XAF1 promoter hypomethylation is associated with high-grade gliomas.

  6. human genome-wide gene expression profile assay was used to screen the targets of miR (zeige MLXIP Proteine)-3131. The overexpressed miR (zeige MLXIP Proteine)-3131 could lead to a significant decrease of DTHD1 and XAF1 mRNA level.

  7. XAF1 acts as a feedback regulator of the TNF (zeige TNF Proteine) receptor signaling pathway to suppress NF-kappaB (zeige NFKB1 Proteine) activation

  8. Taken together, our results suggest that ROS (zeige ROS1 Proteine) generation might be a predisposing event in berberine-induced mitochondrial apoptosis in EBV-transformed B cells through the upregulation of XAF1 and GADD45alpha (zeige GADD45A Proteine) expression by MAPK (zeige MAPK1 Proteine) and functional p53 (zeige TP53 Proteine).

  9. Expression of XAF1 and TAp73 (zeige TP73 Proteine) was also upregulated in casticin-treated T24 cells.

  10. Data show that X-linked inhibitor of apoptosis protein (XIAP (zeige XIAP Proteine)) mRNA and protein expression increased, whereas XIAP-associated factor 1 (XAF1) mRNA and protein expression decreased with the growth of radiation dose and exposure time.

Mouse (Murine) XiAP Associated Factor 1 (XAF1) Interaktionspartner

  1. XAF1 may be a candidate tumor suppressor in neuroblastoma (zeige ARHGEF16 Proteine)

  2. Interferon gamma (zeige IFNG Proteine) induces XAF1 and Noxa (zeige PMAIP1 Proteine) expression and potentiates apoptosis by STAT3 (zeige STAT3 Proteine) activation

  3. XAF1 possesses a potential antiangiogenesis effect. Suppressed expression of Tie-1 (zeige TIE1 Proteine), Ang-1 (zeige ANGPT1 Proteine), Ang-2 (zeige ANGPT2 Proteine) and c-Myc (zeige MYC Proteine) may be mechanistically responsible for the observed antiangiogenesis effect.

XAF1 Protein Überblick

Protein Überblick

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit XAF1

  • XIAP associated factor 1 (xaf1)
  • XIAP associated factor 1 (XAF1)
  • XIAP associated factor 1 (Xaf1)
  • BIRC4BP Protein
  • Fbxo39 Protein
  • HSXIAPAF1 Protein
  • XIAPAF1 Protein

Bezeichner auf Proteinebene für XAF1

XIAP-associated factor 1 , BIRC4 binding protein , BIRC4-binding protein , F-box protein 39 , novel TRAF-type zinc finger protein

767709 Danio rerio
54739 Homo sapiens
327959 Mus musculus
509740 Bos taurus
679600 Rattus norvegicus
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