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WDR3 encodes a nuclear protein containing 10 WD repeats. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal WDR3 Primary Antibody für IP, WB - ABIN262246
McMahon, Ayllón, Panov, OConnor: Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation. in The Journal of biological chemistry 2010
evaluated the genetic association of WDR3 and ALG1 in schizophrenia. We examined 21 single nucleotide polymorphisms [SNPs; W1 (rs1812607)-W16 (rs6656360), A1 (rs8053916)-A10 (rs9673733)] from these genes using the Japanese case-control sample (1,808 schizophrenics and 2,170 matched controls). No significant genetic associations of these SNPs were identified. However, we detected a significant association of W4 (rs319471)
WDR3 can modulate genome stability in thyroid cancer patients.
results indicate for the first time that WDR3 is a risk factor to thyroid cancer, suggesting its implication in the etiology of thyroid cancer
WDR3 has an essential function in 40 S ribosomal subunit synthesis and in ribosomal stress signaling to p53 (zeige TP53 Antikörper)-mediated regulation of cell cycle progression in cancer cells
This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
WD repeat-containing protein 3
, WD repeat domain 3
, WD repeat-containing protein 3-like
, dJ776P7.2 (WD repeat domain 3)