WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Proteine (WFIKKN2)

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain.

alle Proteine anzeigen Gen GeneID UniProt
Human WFIKKN2 WFIKKN2 124857 Q8TEU8
Maus WFIKKN2 WFIKKN2 278507 Q7TQN3
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Top WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Proteine auf antikoerper-online.de

Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Human Cells Human His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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CHO Cells Human Unkonjugiert   25 μg Anmelden zum Anzeigen 8 bis 11 Tage
$328.90
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Hamster Human Unkonjugiert   25 μg Anmelden zum Anzeigen 11 bis 12 Tage
$441.60
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Weitere Proteine zu WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Interaktionspartnern

Human WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Interaktionspartner

  1. In this review, we summarize current knowledge about the WFIKKN (zeige WFIKKN1 Proteine) proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB (zeige TGFB1 Proteine) proteins to their respective receptors, thus regulating the balance between the activation of Smad (zeige SMAD1 Proteine) and non-Smad (zeige SMAD1 Proteine) pathways by TGFB (zeige TGFB1 Proteine).

  2. WFIKKN2 expression is significantly downregulated in human masticatory mucosa during wound healing

  3. Data suggest that myostatin (zeige MSTN Proteine) binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 (zeige WFIKKN1 Proteine) but not WFIKKN2; various forms of myostatin (zeige MSTN Proteine) (promyostatin, myostatin (zeige MSTN Proteine) pro-domain, and latent/processed myostatin (zeige MSTN Proteine)) bind WFIKKN1 (zeige WFIKKN1 Proteine) but not WFIKKN2.

  4. After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of GASP-1 (zeige GPRASP1 Proteine) while postmenopausal women using HT showed a significant increased expression over controls.

  5. data indicate that WFIKKN (zeige WFIKKN1 Proteine) proteins are antagonists of GDF8 (zeige MSTN Proteine) and GDF11 (zeige GDF11 Proteine), but in the case of TGFbeta1 (zeige TGFB1 Proteine), BMP2 (zeige BMP2 Proteine) and BMP4 (zeige BMP4 Proteine) they function as growth factor binding proteins

  6. Creatine supplementation in conjunction with resistance training lead to greater decreases in serum myostatin (zeige MSTN Proteine) (p<0.05), but had not additional effect on GASP-1 (zeige GPRASP1 Proteine) (p>0.05).

  7. Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN (zeige WFIKKN1 Proteine) gene in adult and fetal tissues and organs

  8. Both WFIKKN1 (zeige WFIKKN1 Proteine) and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.

Mouse (Murine) WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Interaktionspartner

  1. Taken together, this study provides evidence that GASP1 (zeige GPRASP1 Proteine) regulates CB1 (zeige CNR1 Proteine) receptor downregulation in vivo, and that postendocytic receptor trafficking has a key role in the development of tolerance to WIN55,212-2.

  2. Report of the identification of growth and differentiation factor-associated serum protein-1 (GASP-1) associated with endogenous myostatin (zeige MSTN Proteine) in normal serum

WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Protein Überblick

Protein Überblick

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.

Genbezeichner und Symbole assoziert mit WFIKKN2

  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 (WFIKKN2)
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 (Wfikkn2)
  • 2610304F08Rik Protein
  • AY100450 Protein
  • GASP-1 Protein
  • Gasp1 Protein
  • hGASP-1 Protein
  • WFDC20B Protein
  • WFIKKNRP Protein

Bezeichner auf Proteinebene für WFIKKN2

WAP four-disulfide core domain 20B , WAP, FS, Ig, two KU and NTR module related protein , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 , WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein , WFIKKN-related protein , growth and differentiation factor-associated serum protein 1 , multivalent protease inhibitor protein , GASP-1 , mGASP-1

GENE ID SPEZIES
124857 Homo sapiens
278507 Mus musculus
531979 Bos taurus
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