WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) ELISA Kits

WFIKKN1 encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. Zusätzlich bieten wir Ihnen WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 Antikörper (7) und WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
WFIKKN1 117166 Q96NZ8
WFIKKN1 363555 P0C5J5
WFIKKN1 215001 Q8R0S6
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Top WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.078 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
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Maus
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Ratte
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Weitere ELISA Kits für WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 Interaktionspartner

Human WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) Interaktionspartner

  1. In this review, we summarize current knowledge about the WFIKKN proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB (zeige TGFB1 ELISA Kits) proteins to their respective receptors, thus regulating the balance between the activation of Smad (zeige SMAD1 ELISA Kits) and non-Smad (zeige SMAD1 ELISA Kits) pathways by TGFB (zeige TGFB1 ELISA Kits).

  2. Data show that the KKN1 fragment generated by BMP1 (zeige BMP1 ELISA Kits)-cleavage of WFIKKN1 protein contributes most significantly to the observed enhancer activity.

  3. Data suggest that myostatin (zeige MSTN ELISA Kits) binding to its receptor (activin (zeige Actbeta ELISA Kits) receptors type II) can be blocked by WFIKKN1 but not WFIKKN2 (zeige WFIKKN2 ELISA Kits); various forms of myostatin (zeige MSTN ELISA Kits) (promyostatin, myostatin (zeige MSTN ELISA Kits) pro-domain, and latent/processed myostatin (zeige MSTN ELISA Kits)) bind WFIKKN1 but not WFIKKN2 (zeige WFIKKN2 ELISA Kits).

  4. data indicate that WFIKKN proteins are antagonists of GDF8 (zeige MSTN ELISA Kits) and GDF11 (zeige GDF11 ELISA Kits), but in the case of TGFbeta1 (zeige TGFB1 ELISA Kits), BMP2 (zeige BMP2 ELISA Kits) and BMP4 (zeige BMP4 ELISA Kits) they function as growth factor binding proteins

  5. Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN gene in adult and fetal tissues and organs.

  6. Data suggest that the physiological target of WFIKKN protein may be trypsin.

  7. three-dimensional structure of a Kunitz domain with a tryptophan residue at the P02 (zeige TPT1 ELISA Kits) site of the protease-recognition loop

  8. Both WFIKKN1 and WFIKKN2 (zeige WFIKKN2 ELISA Kits) have high affinity for growth and differentiation factors 8 and 11.

Mouse (Murine) WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) Interaktionspartner

  1. GASP-1 (zeige GPRASP1 ELISA Kits) and GASP-2 are important modulators of GDF-11 (zeige GDF11 ELISA Kits) and MSTN (zeige MSTN ELISA Kits) activity in vivo.

WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) Antigen-Profil

Beschreibung des Gens

This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.

Genbezeichner und Symbole assoziert mit WFIKKN1

  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (WFIKKN1) Antikörper
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (Wfikkn1) Antikörper
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (wfikkn1) Antikörper
  • WAP, FS, Ig, KU, and NTR-containing protein 1 (Wfikkn1) Antikörper
  • C16orf12 Antikörper
  • Gasp2 Antikörper
  • Oc29 Antikörper
  • RGD1565835 Antikörper
  • RJD2 Antikörper
  • WFDC20A Antikörper
  • wfikkn Antikörper
  • WFIKKN1 Antikörper
  • zgc:85816 Antikörper

Bezeichner auf Proteinebene für WFIKKN1

GASP-2 , WAP four-disulfide core domain 20A , WAP, FS, Ig, KU, and NTR-containing protein , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 , WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing protein , growth and differentiation factor-associated serum protein 2 , hGASP-2 , WAP, FS, Ig, KU, and NTR-containing protein 1 , WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 , WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 , WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1-like , mGASP-2 , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein

GENE ID SPEZIES
117166 Homo sapiens
363555 Rattus norvegicus
429301 Gallus gallus
490094 Canis lupus familiaris
540233 Bos taurus
722338 Macaca mulatta
100066872 Equus caballus
100137288 Papio anubis
100473789 Ailuropoda melanoleuca
100490754 Xenopus (Silurana) tropicalis
100619314 Monodelphis domestica
215001 Mus musculus
406570 Danio rerio
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