anti-Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Antikörper

UBTF encodes a member of the HMG-box DNA-binding protein family. Zusätzlich bieten wir Ihnen Upstream Binding Transcription Factor, RNA Polymerase I Proteine (4) und Upstream Binding Transcription Factor, RNA Polymerase I Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBTF 7343 P17480
UBTF 21429  
UBTF 25574 P25977
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Top anti-Upstream Binding Transcription Factor, RNA Polymerase I Antikörper auf antikoerper-online.de

Showing 10 out of 96 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-UBTF Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Ubtf <br /> Sample Tissue: Rat Spleen lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HeLa/Jurkat cells, using UBF1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using UBF1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to UBTF on HeLa cell (antibody concentration 10 µg/mL). UBTF monoclonal antibody (M01), clone 6B6 Western Blot analysis of UBTF expression in HeLa NE. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of UBF staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of UBF expression in Jurkat (A), rat muscle (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with calyculinA 50ng/ml 30', using UBF (Phospho-Ser484) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using UBF (Phospho-Ser484) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB UBTF Antibody (C-term) (ABIN656478) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the UBTF antibody detected the UBTF protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to UBTF on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to UBTF on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: UBTF Antibody  - Analysis in human cell line MOLT-4. Western Blot: UBTF Antibody  - Analysis in mouse cerebral cortex tissue. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Maus Unkonjugiert IF, ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details

UBTF Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Upstream Binding Transcription Factor, RNA Polymerase I Antikörper

  1. Human Monoclonal UBTF Primary Antibody für IF, IHC (p) - ABIN563329 : Østrup, Petrovicova, Strejcek, Morovic, Lucas-Hahn, Lemme, Petersen, Niemann, Laurincik, Maddox-Hyttel: Nuclear and nucleolar reprogramming during the first cell cycle in bovine nuclear transfer embryos. in Cloning and stem cells 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal UBTF Primary Antibody für ICC, IF - ABIN4364030 : Sobol, Yildirim, Philimonenko, Marášek, Castaño, Hozák: UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity. in Nucleus (Austin, Tex.) 2014 (PubMed)

Weitere Antikörper gegen Upstream Binding Transcription Factor, RNA Polymerase I Interaktionspartner

Human Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Interaktionspartner

  1. TP53INP2 (zeige TP53INP2 Antikörper) promotes ribosome biogenesis through facilitating rRNA synthesis at the nucleolus

  2. Study demonstrated that HMG (zeige SSRP1 Antikörper) box 1, the linker region between the HMG (zeige SSRP1 Antikörper) boxes and C-terminal acidic region (AR), and the AR cooperatively regulate the nucleolar localization of UBF.

  3. In seven unrelated affected individuals, all suffering from developmental regression starting at 2.5-7 years, the authors identified a heterozygous variant, c.628G>A in UBTF, encoding p.Glu210Lys in UBF, which occurred de novo in all cases.

  4. RINT-1 (zeige RINT1 Antikörper) interacts with MSP58 (zeige MCRS1 Antikörper) and UBF within nucleoli and plays a role in ribosomal gene transcription.

  5. This study provides some compelling evidences in support of HBx-elicited and c-Myc (zeige MYC Antikörper)-mediated increase in UBF levels that abets oncogenic onslaught in hepatic cells by increasing rDNA transcription and ribosome biogenesis.

  6. These results suggest that UBF can inhibit gene expression from viral DNA prior to its replication.

  7. we have uncovered a novel role for UBTF1 and UBTF2 in maintaining genome stability through coordinating the expression of highly transcribed Pol I (UBTF1 activity) and Pol II (zeige 0 Antikörper) genes (UBTF2 activity).

  8. p14ARF fails to prevent E7-mediated UBF1 phosphorylation, but could facilitate nucleolar pRb (zeige RB1 Antikörper) inactivation by targeting E7 to the nucleolus.

  9. PIP2 depletion reduces Pol I transcription.

  10. UBF is expressed widely by human multiple fetal tissue,s and the expression level is very high in HL-60 cells.

Mouse (Murine) Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Interaktionspartner

  1. UBF and Nopp140 (zeige NOLC1 Antikörper) dynamic redistribution between the two-cell and blastocyst stages (time of implantation) is correlated with morphological and structural modifications that occur in embryonic nucleolar compartments.

  2. inhibition of UBF function is a major factor in the cytotoxicity of cisplatin; its depletion selectively induces p53 (zeige TP53 Antikörper)-independent apoptotic death in transformed cells

  3. Loss of UBF also unexpectedly induced the formation in cells of a large sub-nuclear structure resembling the nucleolar precursor body (NPB (zeige NPB Antikörper)) of oocytes and early embryos.

  4. we have uncovered a novel role for UBTF1 and UBTF2 in maintaining genome stability through coordinating the expression of highly transcribed Pol I (UBTF1 activity) and Pol II (zeige 0 Antikörper) genes (UBTF2 activity).

  5. UBF1 mutation (K352A, K352Q, and K352R) decreased rDNA transcriptional activity.

  6. augmented ribosome biogenesis occurs in UBF-dependent manner during increased protein synthesis induced by high glucose in glomerular epithelial cells that correlates with UBF activation and renal hypertrophy in rodents with type 1 and type 2 diabetes.

  7. increased UBF levels correlate with elevated pressure load and increased cardiac growth rates

  8. mTOR (zeige FRAP1 Antikörper) plays a critical role in the regulation of ribosome biogenesis via a mechanism that requires S6K1 (zeige RPS6KB1 Antikörper) activation and phosphorylation of UBF.

  9. effects of PES1 (zeige PES1 Antikörper) and UBF1 expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (zeige IL-3 Antikörper))-dependent murine myeloid cell line

  10. Phosphatidylinositol 3-kinase subunit directly phosphorylates and activates UBF1, an exclusively nucleolar protein (zeige MCRS1 Antikörper).

Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Antigen-Profil

Protein Überblick

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Genbezeichner und Symbole assoziert mit UBTF

  • upstream binding transcription factor, RNA polymerase I (ubtf) Antikörper
  • upstream binding transcription factor, RNA polymerase I (UBTF) Antikörper
  • upstream binding transcription factor, RNA polymerase I (Ubtf) Antikörper
  • A930005G04Rik Antikörper
  • NOR-90 Antikörper
  • si:dz180g5.3 Antikörper
  • Tcfubf Antikörper
  • ubf Antikörper
  • UBF-1 Antikörper
  • UBF1 Antikörper
  • UBTF Antikörper
  • wu:fj38c10 Antikörper
  • xUBF Antikörper

Bezeichner auf Proteinebene für UBTF

upstream binding transcription factor, RNA polymerase I , nucleolar transcription factor 1-like , 90-kDa nucleolus organizer region autoantigen , autoantigen NOR-90 , nucleolar transcription factor 1 , UBF-1 , transcription factor UBF , upstream-binding factor 1

GENE ID SPEZIES
368509 Danio rerio
454726 Pan troglodytes
497012 Bos taurus
100019759 Monodelphis domestica
100064724 Equus caballus
100135747 Xenopus (Silurana) tropicalis
100454637 Pongo abelii
100483006 Ailuropoda melanoleuca
100511403 Sus scrofa
100558152 Anolis carolinensis
7343 Homo sapiens
21429 Mus musculus
25574 Rattus norvegicus
480503 Canis lupus familiaris
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