Unc-5 Homolog B (C. Elegans) (UNC5B) ELISA Kits

UNC5B encodes a member of the netrin family of receptors. Zusätzlich bieten wir Ihnen Unc-5 Homolog B (C. Elegans) Antikörper (55) und Unc-5 Homolog B (C. Elegans) Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus UNC5B UNC5B 107449 Q8K1S3
UNC5B 60630 O08722
UNC5B 219699 Q8IZJ1
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Top Unc-5 Homolog B (C. Elegans) ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
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  96 Tests Anmelden zum Anzeigen 31 bis 41 Tage
$734.80
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Weitere ELISA Kits für Unc-5 Homolog B (C. Elegans) Interaktionspartner

Zebrafish Unc-5 Homolog B (C. Elegans) (UNC5B) Interaktionspartner

  1. Disruption of the Unc5b or netrin-1a leads to aberrant extension of endothelial tip cell filopodia, excessive vessel branching and abnormal navigation

  2. A role of axon guidance genes in embryonic hindbrain patterning.

  3. UNC5B-mediated signaling is a specific and autonomous component of fetal-placental angiogenesis.

Mouse (Murine) Unc-5 Homolog B (C. Elegans) (UNC5B) Interaktionspartner

  1. Negative regulation of Naa10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation.

  2. fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of the UNC5 receptor family for neurons, is unexpectedly expressed in endothelial cells specifically in the placental labyrinth.

  3. Blockade of Netrin-1/Unc5b by monoclonal antibodies prevents bone destruction and reduces the severity of K/BxN serum transfer-induced arthritis

  4. Data showed that albuminuria was significantly more pronounced in mice with proximal tubule specific deletion of UNC5B.

  5. UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis.

  6. unc5b expression is greater in adipose tissue of obese versus lean mice.

  7. UNC5B plays a critical role in cell survival and kidney injury through Akt-mediated inactivation of p53 in response to stress.

  8. These studies demonstrate an important role for UNC5B during myocardial ischemia-reperfusion injury.

  9. a significant role for UNC5B in the development of hepatic IRI and identified UNC5B as a potential drug target to prevent liver dysfunction in the future.

  10. Robo4 specifically binds to UNC5B, a vascular Netrin receptor, revealing unexpected interactions between two endothelial guidance receptors.

  11. Netrin-1 acting through the UNC5B receptor reduces renal ischemia-reperfusion injury and its associated renal inflammation.

  12. Unc5h2 was cloned; its mRNA is observed during early blood vessel formation, in the semicircular canal and in a dorsal to ventral gradient in the retina in developing mouse

  13. Disruption of the Unc5b gene leads to aberrant extension of endothelial tip cell filopodia, excessive vessel branching and abnormal navigation

  14. UNC5H2 physically interacts with the serine/threonine kinase death-associated protein kinase (DAP-kinase).

  15. The crystal structure of the mouse UNC5H2 death domain has been determined at 2.1 A resolution.

  16. UNC5B-mediated signaling is a specific and autonomous component of fetal-placental angiogenesis.

  17. PIKE-L acts as a downstream survival effector for netrin-1 through UNC5B in the nervous system

  18. Netrin-4 significantly reduced pathological angiogenesis in Matrigel and laser-induced choroidal neovascularization models. Netrin-4, neogenin, and Unc5B receptor expression was up-regulated in choroidal neovessel EC after laser injury

  19. Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor.

Human Unc-5 Homolog B (C. Elegans) (UNC5B) Interaktionspartner

  1. Negative regulation of Naa10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation.

  2. These findings point to a new important function of UNC5B and provide a potential basis for hASCs-mediated bone regeneration.

  3. Our results suggest that UNC5B overexpression inhibits the proliferation and migration of bladder cancer cells by inducing cell cycle arrest at G2/M phase.

  4. UNC5B expression is decreased in bladder cancer cells compared to normal bladder cell lines.

  5. Data indicate that dysregulation of expression of netrin-1 NTN1 in smooth muscle cell (SMC) and its chemorepulsive receptor UNC5B in macrophages are involved in the development of atherosclerosis and unstable plaques.

  6. unc5b expression is greater in adipose tissue of obese versus lean subjects.

  7. Higher netrin-1 and lower UNC5B expression in all prostate carcinoma cell lines indicated that netrin-1 and UNC5B could be used to predict metastasis.

  8. Low UNC5B expression was an independent risk factor for postoperative recurrence in patients with different stages and grades bladder cancer.

  9. UNC5B protein expressed in macrophages in hypoxic regions of atherosclerotic regions in human.

  10. UNC5B was downregulated in kidney carcinoma.

  11. Reducing Unc5b levels in Sip1 knockout slices and brains rescues cell migration in cortical interneurons.

  12. Hypoxia-inducible factor 1 controls the expression of the uncoordinated-5-B receptor, but not of netrin-1, in first trimester human placenta

  13. The mRNA expression analysis using tissue samples revealed that UNC5B mRNA was down-expressed in about 20% of CRC patients, and the patients with low-UNC5B-expression tumors showed a significantly higher recurrence rate after curative surgery.

  14. Netrin-1 can promote the potential of proliferation and invasion of extravillous trophoblasts in vitro through its receptors neogenin and UNC5B.

  15. Robo4 specifically binds to UNC5B, a vascular Netrin receptor, revealing unexpected interactions between two endothelial guidance receptors.

  16. The recruitment of PP2A to UNC5H2/B allows the activation of DAPk via a PP2A-mediated dephosphorylation and that this mechanism is involved in angiogenesis regulation.

  17. Down-regulation of UNC5b gene expression is related to angiogenesis of hepatocellular carcinoma.

  18. UNC5B receptor is localized to villous and extravillous cytotrophoblasts proximal to anchoring areas during the first trimester.

  19. Modulation of G(ialpha(2)) signaling by the axonal guidance of this protein

  20. may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis

Pig (Porcine) Unc-5 Homolog B (C. Elegans) (UNC5B) Interaktionspartner

  1. findings show that the netrin-1 and p53RDL1 system may regulate the induction of apoptosis in porcine granulosa cells

Unc-5 Homolog B (C. Elegans) (UNC5B) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

Genbezeichner und Symbole assoziert mit UNC5B

  • unc-5 netrin receptor B (unc5b) Antikörper
  • unc-5 netrin receptor B (Unc5b) Antikörper
  • unc-5 netrin receptor B (UNC5B) Antikörper
  • unc-5 netrin receptor B L homeolog (unc5b.L) Antikörper
  • 6330415E02Rik Antikörper
  • A630020F16 Antikörper
  • D10Bwg0792e Antikörper
  • p53rdl1 Antikörper
  • UNC5B Antikörper
  • UNC5C Antikörper
  • UNC5H2 Antikörper

Bezeichner auf Proteinebene für UNC5B

netrin receptor UNC5B , protein unc-5 homolog 2 , protein unc-5 homolog B , unc-5 homolog 2 , unc5 homolog 2 , UNC5H2 , transmembrane receptor Unc5H2 , p53-regulated receptor for death and life protein 1 , unc-5 homolog C , p53-regulated receptor for death and life , unc-5 homolog B (C. elegans) , UNC-5 receptor , protein Xunc-5 , protein unc-5 homolog

GENE ID SPEZIES
494130 Danio rerio
107449 Mus musculus
423716 Gallus gallus
60630 Rattus norvegicus
219699 Homo sapiens
524942 Bos taurus
733600 Sus scrofa
479239 Canis lupus familiaris
715786 Macaca mulatta
100072764 Equus caballus
398393 Xenopus laevis
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