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UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR\; MIM 607311) and HSP90 (HSPCA\; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]\; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen UNC45A Antikörper (34) und UNC45A Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
There is no functional redundancy between Unc45a and Unc45b (zeige UNC45B ELISA Kits) in vivo.
The results are the first to ascribe a role for Unc45a, a putative myosin chaperone, in vertebrate development, and identify a novel mechanism by which an arteriovenous malformation can form.
UNC-45a promotes generation of contractile actomyosin bundles through synchronized non-muscle myosin II folding and filament-assembly activities.
Results provide novel insights into the molecular mechanisms of neurite growth and define UNC-45A as a novel and master regulator of NMII-mediated cellular processes in neurons.
UNC-45A is a crucial component in regulating human NK cell cytoskeletal dynamics via promoting the formation of actomyosin complexes.
Findings identify a novel centrosomal function for UNC45A and its role in cell proliferation and tumorigenesis.
The authors found that UNC-45A is alternatively expressed at the mRNA and protein levels as two isoforms and that the two isoforms differ only by a proline-rich 15-amino-acid sequence near the amino-terminus.
GCUNC-45 is a novel modulator of progesterone receptor (zeige PGR ELISA Kits) chaperoning by hsp90 (zeige HSP90 ELISA Kits).
elevated GC UNC-45 protein expression in ovarian carcinoma proliferation and metastasis.
GCUNC45 is required for the normal cellular distribution of Hsp90beta, but not Hsp90alpha.
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR\; MIM 607311) and HSP90 (HSPCA\; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002
unc-45 homolog A (C. elegans)
, unc-45 homolog A
, protein unc-45 homolog A
, general cell UNC45
, smooth muscle cell associated protein-1
, smooth muscle cell-associated protein 1
, stromal membrane-associated protein 1
, UNC45 homolog A