Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) Proteine (Galnt1)

Galnt1 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Zusätzlich bieten wir Ihnen Galnt1 Antikörper (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Galnt1 14423 O08912
Galnt1 2589 Q10472
Galnt1 79214 Q10473
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Showing 6 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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Baculovirus infected Insect Cells Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$1,230.77
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,600.67
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Galnt1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
,
Human , ,
, , ,
Rat (Rattus)

Weitere Proteine zu Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartnern

Mouse (Murine) Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartner

  1. Study show that in Galnt1 null mouse, there is compromised cardiac function that mimics human congenital heart disease suggesting that Galnt1 expression is required for normal heart valve development.

  2. The GALNT1 is the glycosyltransferase (zeige GTDC2 Proteine) enzyme family covering a single known glycosidic linkage.

  3. Polypeptide GalNAcT (zeige B4GALNT1 Proteine)-1 plays a predominant role in leukocyte recruitment in vivo by attaching functionally relevant O-linked glycans to L-selectin (zeige SELL Proteine) ligands.

  4. Growth factor stimulation regulates O-glycosylation initiation in a Src (zeige SRC Proteine)-dependent fashion by GalNac-T (zeige B4GALNT1 Proteine) redistribution from golgi to the endoplasmic reticulum.

  5. ppGalNAcT-1 to be indispensable for O-glycosylation at specific sites of the bone glycoproteins OPN (zeige SPP1 Proteine) and BSP (zeige KLK6 Proteine).

Human Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartner

  1. We have elucidated a novel miR-30-GALNT1/2 axis whose dysregulation increases the proportion of inactive proBNP secreted by the heart and impairs the compensatory actions of BNP during the progression of heart failure.

  2. the GalNAc-T13 (zeige GALNT13 Proteine) isoform is predicted to function similarly to GalNAc-T1 against peptide substrates in vivo, in contrast to a prior report, but is unique by being selectively expressed in the brain.

  3. Expression of GALNT3 (zeige GALNT3 Proteine) was reduced in CAD patients, and down regulation of GALNT3 (zeige GALNT3 Proteine) contributed to endothelial injury by promoting apoptosis and up-regulating the expression of MMP-2 (zeige MMP2 Proteine) and MMP-14 (zeige MMP14 Proteine) genes via p38 MAPK (zeige MAPK14 Proteine) activation.

  4. appears to be responsive to the inhibition of GALNT1 and SHH (zeige SHH Proteine) signaling

  5. Study demonstrates that down-regulation of GALNT1 is sufficient to suppress malignant phenotype of HCC (zeige FAM126A Proteine) cells by decreasing EGFR (zeige EGFR Proteine) signaling.

  6. The GALNT1 is the glycosyltransferase (zeige GTDC2 Proteine) enzyme family covering a single known glycosidic linkage.

  7. Utilizing unnatural glycopeptide substrates for GalNAc-T3 we demonstrated that the GalNAc-specific sugar recognition of the lectin domain regulates further glycosylation.

  8. Growth factor stimulation regulates O-glycosylation initiation in a Src (zeige SRC Proteine)-dependent fashion by GalNac-T (zeige B4GALNT1 Proteine) redistribution from golgi to the endoplasmic reticulum.

  9. the present analysis fails to replicate an earlier reported association of a GALNT1 variant with risk of ovarian cancer

  10. First simultaneous kinetic description of O-glycosylation events by recombinant UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (zeige B4GALNT2 Proteine) I at all putative O-glycosylation sites within human mucin (zeige SLC13A2 Proteine) MUC1 (zeige MUC1 Proteine) containing 5 tandem repeats.

Galnt1 Protein Überblick

Protein Überblick

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature.

Genbezeichner und Symbole assoziert mit Galnt1

  • polypeptide N-acetylgalactosaminyltransferase 1 L homeolog (galnt1.L)
  • polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1)
  • polypeptide N-acetylgalactosaminyltransferase 1 (galnt1)
  • polypeptide N-acetylgalactosaminyltransferase 1 (LOC100181305)
  • polypeptide N-acetylgalactosaminyltransferase 1 (Galnt1)
  • GALNAC-T1 Protein
  • GALNT1 Protein

Bezeichner auf Proteinebene für Galnt1

polypeptide N-acetylgalactosaminyltransferase 1 , UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) , polypeptide N-acetylgalactosaminyltransferase 1-like , UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 , galNAc-T1 , polypeptide GalNAc transferase 1 , pp-GaNTase 1 , ppGaNTase-T1 , protein-UDP acetylgalactosaminyltransferase 1 , GalNAc transferase 1 , polypeptide GalNAc transferase T1

GENE ID SPEZIES
398911 Xenopus laevis
420955 Gallus gallus
468521 Pan troglodytes
480161 Canis lupus familiaris
594943 Xenopus (Silurana) tropicalis
708930 Macaca mulatta
100010982 Monodelphis domestica
100181305 Ciona intestinalis
100229109 Taeniopygia guttata
100390797 Callithrix jacchus
100439914 Pongo abelii
100466565 Ailuropoda melanoleuca
100544386 Meleagris gallopavo
100553448 Anolis carolinensis
100605635 Nomascus leucogenys
100738545 Sus scrofa
14423 Mus musculus
2589 Homo sapiens
79214 Rattus norvegicus
282241 Bos taurus
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