Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) Proteine (Galnt1)

Galnt1 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Zusätzlich bieten wir Ihnen Galnt1 Antikörper (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Galnt1 14423 O08912
Galnt1 2589 Q10472
Galnt1 79214 Q10473
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top Galnt1 Proteine auf antikoerper-online.de

Showing 6 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
Details
Baculovirus infected Insect Cells Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$1,230.77
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$325.44
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$814.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,600.67
Details

Galnt1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
,
Human , ,
, , ,
Rat (Rattus)

Weitere Proteine zu Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartnern

Mouse (Murine) Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartner

  1. the ppGalNAc-T4 was highly expressed in MC3T3-E1 cells during osteogenesis for the first time; ppGalNAc-T1 and -T4 affected the expression of different osteogenic factors, suggesting distinct roles ppGalNAc-T isoforms play in regulating osteogenesis in vitro

  2. Study show that in Galnt1 null mouse, there is compromised cardiac function that mimics human congenital heart disease suggesting that Galnt1 expression is required for normal heart valve development.

  3. The GALNT1 is the glycosyltransferase enzyme family covering a single known glycosidic linkage.

  4. Polypeptide GalNAcT-1 plays a predominant role in leukocyte recruitment in vivo by attaching functionally relevant O-linked glycans to L-selectin ligands.

  5. each ppGalNAc T isoform may be uniquely sensitive to peptide sequence and overall charge, which together dictates the substrate sites that will be glycosylated

  6. Growth factor stimulation regulates O-glycosylation initiation in a Src-dependent fashion by GalNac-T redistribution from golgi to the endoplasmic reticulum.

  7. ppGalNAcT-1 to be indispensable for O-glycosylation at specific sites of the bone glycoproteins OPN and BSP.

  8. These findings reveal that the initiation of protein O glycosylation by ppGalNAcT-1 provides a distinctive repertoire of advantageous functions that support vascular responses and humoral immunity.

Human Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaktionspartner

  1. We have elucidated a novel miR-30-GALNT1/2 axis whose dysregulation increases the proportion of inactive proBNP secreted by the heart and impairs the compensatory actions of BNP during the progression of heart failure.

  2. the GalNAc-T13 isoform is predicted to function similarly to GalNAc-T1 against peptide substrates in vivo, in contrast to a prior report, but is unique by being selectively expressed in the brain.

  3. Expression of GALNT3 was reduced in CAD patients, and down regulation of GALNT3 contributed to endothelial injury by promoting apoptosis and up-regulating the expression of MMP-2 and MMP-14 genes via p38 MAPK activation.

  4. appears to be responsive to the inhibition of GALNT1 and SHH signaling

  5. Study demonstrates that down-regulation of GALNT1 is sufficient to suppress malignant phenotype of HCC cells by decreasing EGFR signaling.

  6. High ppGalNAc T1 expresdsion is associated with bladder cancer.

  7. The GALNT1 is the glycosyltransferase enzyme family covering a single known glycosidic linkage.

  8. Utilizing unnatural glycopeptide substrates for GalNAc-T3 we demonstrated that the GalNAc-specific sugar recognition of the lectin domain regulates further glycosylation.

  9. each ppGalNAc T isoform may be uniquely sensitive to peptide sequence and overall charge, which together dictates the substrate sites that will be glycosylated

  10. Growth factor stimulation regulates O-glycosylation initiation in a Src-dependent fashion by GalNac-T redistribution from golgi to the endoplasmic reticulum.

  11. the present analysis fails to replicate an earlier reported association of a GALNT1 variant with risk of ovarian cancer

  12. First simultaneous kinetic description of O-glycosylation events by recombinant UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase I at all putative O-glycosylation sites within human mucin MUC1 containing 5 tandem repeats.

  13. The results indicated that IL-4-treated LS174T cells are able to produce mucins with a higher degree of O-glycosylation than untreated counterparts.

  14. GalNAc T10 has a large and pronounced glycopeptide preference for Ser/Thr-O-GalNAc only at the +1 position from the acceptor site, whereas T1 and T2 have significantly reduced and variable preferences for Ser/Thr-O-GalNAc.

  15. A direct link between miR-129 and the two putative targets GALNT1 and SOX4 in bladder cancer.

  16. Data show that the sequences and O-glycosylation patterns direct the addition of the first and second sugar residues by ppGalNAc-T and C1GalT which act in a site directed fashion.

Galnt1 Protein Überblick

Protein Überblick

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature.

Genbezeichner und Symbole assoziert mit Galnt1

  • polypeptide N-acetylgalactosaminyltransferase 1 L homeolog (galnt1.L)
  • polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1)
  • polypeptide N-acetylgalactosaminyltransferase 1 (galnt1)
  • polypeptide N-acetylgalactosaminyltransferase 1 (LOC100181305)
  • polypeptide N-acetylgalactosaminyltransferase 1 (Galnt1)
  • GALNAC-T1 Protein
  • GALNT1 Protein

Bezeichner auf Proteinebene für Galnt1

polypeptide N-acetylgalactosaminyltransferase 1 , UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) , polypeptide N-acetylgalactosaminyltransferase 1-like , UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 , galNAc-T1 , polypeptide GalNAc transferase 1 , pp-GaNTase 1 , ppGaNTase-T1 , protein-UDP acetylgalactosaminyltransferase 1 , GalNAc transferase 1 , polypeptide GalNAc transferase T1

GENE ID SPEZIES
398911 Xenopus laevis
420955 Gallus gallus
468521 Pan troglodytes
480161 Canis lupus familiaris
594943 Xenopus (Silurana) tropicalis
708930 Macaca mulatta
100010982 Monodelphis domestica
100181305 Ciona intestinalis
100229109 Taeniopygia guttata
100390797 Callithrix jacchus
100439914 Pongo abelii
100466565 Ailuropoda melanoleuca
100544386 Meleagris gallopavo
100553448 Anolis carolinensis
100605635 Nomascus leucogenys
100738545 Sus scrofa
14423 Mus musculus
2589 Homo sapiens
79214 Rattus norvegicus
282241 Bos taurus
Ausgewählte Anbieter für Galnt1 Proteine (Galnt1)
Haben Sie etwas anderes gesucht?