anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) Antikörper

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Zusätzlich bieten wir Ihnen USP13 Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP13 8975 Q92995
USP13 72607 Q5BKP2
USP13    
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Top anti-USP13 Antikörper auf antikoerper-online.de

Showing 10 out of 87 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-USP13 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Placenta WB Suggested Anti-USP13 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from mouse brain cells, using USP13 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using USP13 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-USP13 Pab (ABIN388901) is used in Western blot to detect USP13 in HeLa cell lysate. Detection of USP13 in HeLa cells expressing exogenous USP13 by anti-USP13 Pab (ABIN388901). (Data provided by Amy Chen, Burnham Institute for Medical Research) 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Detection of USP13 in HeLa cells expressing exogenous USP13 by anti-USP13 Pab (ABIN388900). (Data provided by Amy Chen, Burnham Institute for Medical Research) 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Anti-USP13 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104942 dilution 10 ug/ml. Anti-USP13 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details

Am meisten referenzierte anti-USP13 Antikörper

  1. Human Polyclonal USP13 Primary Antibody für ICC, IF - ABIN4364543 : Cheung, Yang, Lee, Rennert, Chan: Hypermethylation of genes in testicular embryonal carcinomas. in British journal of cancer 2016 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen USP13 Interaktionspartner

Human Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) Interaktionspartner

  1. These results reveal an important metabolism-centric role of USP13, which may lead to potential therapeutics targeting USP13 in ovarian cancers.

  2. in the samples of 293T cell lines after the overexpression of USP13 and USP13 C345S, vinculin (zeige VCL Antikörper) exhibited an increased expression, suggesting that it may be a candidate substrate of USP13.

  3. Deubiquitinating enzyme 13 (USP13) regulates myeloid cell leukemia sequence 1 protein (MCL1 (zeige MCL1 Antikörper)) stability in lung and ovarian cancer cells.

  4. our results demonstrate that AR can promote melanoma metastasis via altering the miRNA-539-3p/USP13/MITF (zeige MITF Antikörper)/AXL (zeige AXL Antikörper) signal and targeting this newly identified signal with AR degradation enhancer ASC (zeige PYCARD Antikörper)-J9 may help us to better suppress the melanoma metastasis.

  5. USP13 and FBXL14 (zeige FBXL14 Antikörper) play opposing roles in the regulation of glioma stem cells (GSCs) through reversible ubiquitination of c-Myc (zeige MYC Antikörper).

  6. Down-regulation of USP13 mediates PTEN protein loss and fibroblast phenotypic change, and thereby plays a crucial role in idiopathic pulmonary fibrosis pathogenesis.

  7. The authors identify USP13 as a gp78 (zeige AMFR Antikörper)-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A (zeige UBL4A Antikörper) to maintain the functionality of Bag6 (zeige BAT3 Antikörper).

  8. USP13 is a tumour-suppressing protein that functions through deubiquitylation and stabilization of PTEN.

  9. to our knowledge, USP13 is the first deubiquitinating enzymes identified to modulate STAT1 and play a role in the antiviral activity of IFN against DEN-2 replication.

  10. USP10 (zeige USP10 Antikörper) mediates the deubiquitination of p53 (zeige TP53 Antikörper), regulating deubiquitination activity of USP10 (zeige USP10 Antikörper) and USP13 by Beclin1 (zeige BECN1 Antikörper) provides a mechanism for Beclin1 (zeige BECN1 Antikörper) to control the levels of p53 (zeige TP53 Antikörper).

USP13 Antigen-Profil

Protein Überblick

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Component of a regulatory loop that of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34- containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Mediates stabilization of SIAH2 independently of impairing SIAH2 autoubiquitination. Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains. In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly. Able to cleave ISG15 in vitro\; however, additional experiments are required to confirm such data (By similarity).

Genbezeichner und Symbole assoziert mit USP13

  • ubiquitin specific peptidase 13 (USP13) Antikörper
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (Usp13) Antikörper
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13) Antikörper
  • ubiquitin specific peptidase 13 (usp13) Antikörper
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (usp13) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 13 (MGYG_01656) Antikörper
  • universal stress protein (RR_RS02895) Antikörper
  • 2700071E21Rik Antikörper
  • AI848077 Antikörper
  • IsoT-3 Antikörper
  • ISOT3 Antikörper
  • MGC163140 Antikörper
  • usp13 Antikörper

Bezeichner auf Proteinebene für USP13

deubiquitinating enzyme 13 , isopeptidase T-3 , ubiquitin carboxyl-terminal hydrolase 13 , ubiquitin specific protease 13 (isopeptidase T-3) , ubiquitin thioesterase 13 , ubiquitin thiolesterase 13 , ubiquitin-specific-processing protease 13 , ubiquitin specific peptidase 13 (isopeptidase T-3) , ubiquitin carboxyl-terminal hydrolase 13-like , ubiquitin thiolesterase 13-like , Deubiquitinating enzyme 13 , Ubiquitin thioesterase 13 , Ubiquitin-specific-processing protease 13 , ubiquitin specific peptidase 13 , universal stress protein

GENE ID SPEZIES
8975 Homo sapiens
471009 Pan troglodytes
100524109 Sus scrofa
100346991 Oryctolagus cuniculus
72607 Mus musculus
429286 Gallus gallus
478640 Canis lupus familiaris
496675 Xenopus (Silurana) tropicalis
708624 Macaca mulatta
100013861 Monodelphis domestica
100141289 Bos taurus
100484573 Ailuropoda melanoleuca
100563917 Anolis carolinensis
558011 Danio rerio
10032920 Arthroderma gypseum CBS 118893
3127112 Haloarcula marismortui ATCC 43049
100065844 Equus caballus
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