anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) Antikörper

UBR2 encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Zusätzlich bieten wir Ihnen UBR2 Kits (2) und UBR2 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBR2 23304 Q8IWV8
UBR2 224826 Q6WKZ8
UBR2 363188  
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Top anti-UBR2 Antikörper auf antikoerper-online.de

Showing 10 out of 62 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-UBR2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  MCF7 cell lysate There is BioGPS gene expression data showing that UBR2 is expressed in MCF7 Host:  Rabbit  Target Name:  UBR2  Sample Type:  Human Fetal Brain  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of UBR2 expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Human Ziege Unkonjugiert ELISA, IHC   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Huhn Ziege Unkonjugiert ELISA, IHC, IHC (p) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-UBR2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Maus Ziege Unkonjugiert ELISA, WB Immunohistochemistry-Paraffin: UBR2 Antibody  - Staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis UBR2 using HeLa whole cell lysates ABIN6279403 at 1/100 staining Mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert IF, RNAi, ELISA, WB Western Blot analysis of UBR2 expression in transfected 293T cell line by UBR2 monoclonal antibody (M01), clone 4G4.<br><br>Lane 1: UBR2 transfected lysate(50 KDa).<br>Lane 2: Non-transfected lysate.<br> Western blot analysis of UBR2 over-expressed 293 cell line, cotransfected with UBR2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with UBR2 monoclonal antibody (M01), clone 4G4. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
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Ratte Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

Am meisten referenzierte anti-UBR2 Antikörper

  1. Mouse (Murine) Polyclonal UBR2 Primary Antibody für ELISA, WB - ABIN4250454 : Zenker, Mayerle, Lerch, Tagariello, Zerres, Durie, Beier, Hülskamp, Guzman, Rehder, Beemer, Hamel, Vanlieferinghen, Gershoni-Baruch, Vieira, Dumic, Auslender, Gil-da-Silva-Lopes, Steinlicht, Rauh et al.: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). ... in Nature genetics 2005 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen UBR2 Interaktionspartner

Human Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) Interaktionspartner

  1. There was a significant difference between the oligospermia men (oligospermia group) and the fertile men (control group) observed in this research that could indicate that the combined AT-TC-CC genotype in the UBR2 gene (rs16895863, rs373341, rs3749897 respectively) is a possible risk of idiopathic oligospermia for men in Sichuan, China.

  2. The c.1,066A>T variant in the UBR2 gene is associated with increased susceptibility to azoospermia caused by meiotic arrest.

  3. Study provides functional data for the mouse ubiquitin protein ligase E3 component n-recognin 2 protein.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) Interaktionspartner

  1. Taken together, our findings indicated that p53 (zeige TP53 Antikörper)(-/-) mBMMSC exosomes could deliver UBR2 to target cells and promote gastric cancer growth and metastasis by regulating Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway.

  2. These data suggest that Tex19.1 and Ubr2 are required for mouse spermatocytes to accumulate sufficient Spo11 (zeige SPO11 Antikörper)-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals.

  3. Results suggest that UBR2 up-regulation in cachectic muscle is mediated by the p38beta (zeige MAPK11 Antikörper)-C/EBPbeta (zeige CEBPB Antikörper) signaling pathway responsible for the bulk of tumor-induced muscle proteolysis.

  4. Results suggest that the binding of Ubr2 to Tex19.1 metabolically stabilizes Tex19.1 during spermatogenesis, revealing a new function for Ubr2 outside the conventional N-end rule pathway.

  5. insufficiency in UBR2-dependent histone ubiquitination triggers a pachytene checkpoint system, providing a new insight into chromatin remodeling and gene expression regulation

  6. UBR2 ubiquitin ligase and the N-end rule pathway are required for male meiosis and spermatogenesis and for an essential aspect of female embryonic development.

  7. mouse fibroblast cells derived from Ubr2 deficient embryos display genome instability.

  8. UBR1 (zeige UBR1 Antikörper)-/-UBR2-/- embryos die at midgestation, with defects in neurogenesis and cardiovascular development.

UBR2 Antigen-Profil

Protein Überblick

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit UBR2

  • ubiquitin protein ligase E3 component n-recognin 2 (UBR2) Antikörper
  • ubiquitin protein ligase E3 component n-recognin 2 (ubr2) Antikörper
  • ubiquitin protein ligase E3 component n-recognin 2 S homeolog (ubr2.S) Antikörper
  • ubiquitin protein ligase E3 component n-recognin 2 (Ubr2) Antikörper
  • 9930021A08Rik Antikörper
  • AI462103 Antikörper
  • AW540746 Antikörper
  • bA49A4.1 Antikörper
  • C6orf133 Antikörper
  • dJ242G1.1 Antikörper
  • dJ392M17.3 Antikörper
  • E130209G04Rik Antikörper
  • mKIAA0349 Antikörper
  • RP3-392M17.3 Antikörper
  • si:ch211-239i4.2 Antikörper

Bezeichner auf Proteinebene für UBR2

ubiquitin protein ligase E3 component n-recognin 2 , rp3-392m17.3 , E3 ubiquitin-protein ligase UBR2 , ubiquitin-protein ligase E3-alpha-2 , ubiquitin-protein ligase E3-alpha-II , N-recognin-2 , ubiquitin ligase E3 alpha-II

GENE ID SPEZIES
100522688 Sus scrofa
100009912 Monodelphis domestica
100170193 Xenopus (Silurana) tropicalis
100542516 Meleagris gallopavo
559136 Danio rerio
734725 Xenopus laevis
421387 Gallus gallus
23304 Homo sapiens
474903 Canis lupus familiaris
527153 Bos taurus
224826 Mus musculus
363188 Rattus norvegicus
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