anti-Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Antikörper

The protein encoded by TNFRSF9 is a member of the TNF-receptor superfamily. Zusätzlich bieten wir Ihnen CD137 Proteine (65) und CD137 Kits (31) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNFRSF9 3604 Q07011
TNFRSF9 21942 P20334
TNFRSF9    
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Top anti-CD137 Antikörper auf antikoerper-online.de

Showing 10 out of 325 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Maus Ratte Biotin FACS   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$233.02
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TNFRSF9 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Fetal Liver 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Biotin ELISA   0.5 mg Anmelden zum Anzeigen 6 bis 8 Tage
$535.49
Details
Human Maus Unkonjugiert ELISA   0.5 mg Anmelden zum Anzeigen 6 bis 8 Tage
$370.44
Details
Human Maus PE Func, FACS, IP, ELISA   100 Tests Anmelden zum Anzeigen 5 bis 7 Tage
$366.85
Details
Human Ziege Biotin ELISA (Detection), FACS, ICC, WB Detection of 4-1BB/TNFRSF9/ CD137 in PHA-treated Human T Cells by Flow Cytometry. Human T cells were treated for 48 hours with 5 ug/mL PHA then stained with Human 4-1BB/TNFRSF9/CD137 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 4-1BB/TNFRSF9/CD137 in Human PBMCs. 4-1BB/TNFRSF9/CD137 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using Goat Anti-Human 4-1BB/TNFRSF9/CD137 Biotinylated Antigen Affinity-purified Polyclonal Antibody  at 15 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Streptavidin (red 50 μg Anmelden zum Anzeigen 8 bis 9 Tage
$448.50
Details
Maus Ziege Unkonjugiert Agon, CyTOF, FACS, IHC, WB 4-1BB/TNFRSF9/CD137 in Mouse Spleen. 4-1BB/TNFRSF9/CD137 was detected in perfusion fixed frozen sections of mouse spleen using Goat Anti-Mouse 4-1BB/TNFRSF9/CD137 Antigen Affinity-purified Polyclonal Antibody  at 1.7 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Goat HRP-DAB Cell & Detection of Mouse 4-1BB/TNFRSF9/ CD137 by Western Blot. Western blot shows lysates of NS0 mouse myeloma cell line either mock transfected or transfected with recombinant mouse 4-1BB/Fc chimera. PVDF membrane was probed with 0.5 ug/mL of Goat Anti-Mouse 4-1BB/TNFRSF9/CD137 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from K562 cells, using TNFRSF9 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus PE-Cy7 ELISA 100 Tests Anmelden zum Anzeigen 10 bis 12 Tage
$327.42
Details

TNFRSF9 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CD137 Antikörper

  1. Mouse (Murine) Monoclonal CD137 Primary Antibody für FACS, IP - ABIN1177287 : Chalupny, Peach, Hollenbaugh, Ledbetter, Farr, Aruffo: T-cell activation molecule 4-1BB binds to extracellular matrix proteins. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 11 Pubmed References

  2. Mouse (Murine) Monoclonal CD137 Primary Antibody für FACS - ABIN2688964 : DeBenedette, Chu, Pollok, Hurtado, Wade, Kwon, Watts: Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP. in The Journal of experimental medicine 1995 (PubMed)
    Show all 11 Pubmed References

  3. Human Monoclonal CD137 Primary Antibody für Func, FACS - ABIN610408 : Boulton, Cobb: Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies. in Cell regulation 1991 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD137 Primary Antibody für ELISA - ABIN2688961 : Kim, Broxmeyer: Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8(+) T cells. in Journal of hematotherapy & stem cell research 2001 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal CD137 Primary Antibody für ELISA - ABIN2688963 : Melero, Shuford, Newby, Aruffo, Ledbetter, Hellström, Mittler, Chen: Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. in Nature medicine 1997 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal CD137 Primary Antibody für Func, FACS - ABIN2749106 : Bellarosa, Bressan, Bigioni, Parlani, Maggi, Binaschi: SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line. in International journal of oncology 2013 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD137 Primary Antibody für FACS - ABIN2688962 : Zhou, Kim, Hurtado, Lee, Kim, Pollok, Kwon: Characterization of human homologue of 4-1BB and its ligand. in Immunology letters 1995 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal CD137 Primary Antibody für Func, FACS - ABIN2800694 : Fernández Do Porto, Jurado, Pasquinelli, Alvarez, Aspera, Musella, García: CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis. in Immunology and cell biology 2012 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal CD137 Primary Antibody für Func, FACS - ABIN2749216 : Chan, Voskens, Lin, Schindler, Azimzadeh, Wang, Taylor, Strome, Schulze: Epitope mapping of a chimeric CD137 mAb: a necessary step for assessing the biologic relevance of non-human primate models. in Journal of molecular recognition : JMR 2009 (PubMed)
    Show all 3 Pubmed References

  10. Human Polyclonal CD137 Primary Antibody für Agon, CyTOF - ABIN5012831 : Maerten, Geboes, De Hertogh, Shen, Cadot, Bullens, Van Assche, Penninckx, Rutgeerts, Ceuppens: Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease. in Clinical immunology (Orlando, Fla.) 2004 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen CD137 Interaktionspartner

Human Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Interaktionspartner

  1. Cetuximab-mediated NK-cell expression of CD137 on tumor-infiltrating lymphocytes is dependent on FcgammaRIIIa polymorphism. In neoadjuvant cetuximab-treated patients with head and neck cancer, upregulation of CD137 by intratumoral, cetuximab-activated NK cells correlated with FcgammaRIIIa V/F polymorphism and predicted clinical response.

  2. In this study we systematically evaluated a series of CAR constructs targeting glypican-3 (GPC3 (zeige GPC3 Antikörper)), which is selectively expressed on several solid tumors. We compared GPC3 (zeige GPC3 Antikörper)-specific CARs that encoded CD3zeta (zeige CD247 Antikörper) (Gz) alone or with costimulatory domains derived from CD28 (zeige CD28 Antikörper) (G28z), 4-1BB (GBBz), or CD28 (zeige CD28 Antikörper) and 4-1BB (G28BBz).

  3. 4-1BB and 4-1BBL (zeige TNFSF9 Antikörper) qualify as markers for prediction of patients' course and represent a valuable screening target for patients with acute myeloid leukemia (zeige BCL11A Antikörper) at initial diagnosis.

  4. the role of CD137-CRDI (cysteine rich domain I) in the binding of CD137-CD137L (zeige TNFSF9 Antikörper) was further investigated.

  5. Egr2 (zeige EGR2 Antikörper)-driven cell surface proteins LAG-3 (zeige LAG3 Antikörper) and 4-1BB can identify dysfunctional tumor antigen-specific CD8 (zeige CD8A Antikörper)(+) TIL (zeige TLR1 Antikörper).

  6. Findings indicate that CD137 antigen is a useful marker that can be used for identifying Mycobacterium tuberculosis (Mtb (zeige NCAPG2 Antikörper))-reactive CD4 (zeige CD4 Antikörper)(+) T cells (Mtb (zeige NCAPG2 Antikörper)-reactive CD4 (zeige CD4 Antikörper)(+) T cells) by flow cytometry.

  7. Anti-4-1BB single chain variable fragments enhanced surface CD69 (zeige CD69 Antikörper) expression and interleukin-2 (zeige IL2 Antikörper) production in stimulated CCRF-CEM cells which confirmed the agonistic effect of the selected single chain variable fragments. The data from this study have provided a rationale for further experiments involving the biological functions of anti-4-1BB single chain variable fragments in future studies.

  8. Studies suggest that adoptive T cell therapy and CD137 antigen offer much opportunity to raise the efficacy of current cancer immunotherapies.

  9. Triple costimulation via CD80 (zeige CD80 Antikörper), 4-1BB, and CD83 (zeige CD83 Antikörper) ligand elicits the long-term growth of Vgamma9Vdelta2 T cells in low levels of IL-2 (zeige IL2 Antikörper).

  10. These studies provide the first direct evidence that ligation of tumour necrosis factor (zeige TNF Antikörper) superfamily members and their cognate receptors is important for the control of viral lytic replication.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) Interaktionspartner

  1. fatty acid metabolism plays a crucial role in enhancing the cell cycle progression of anti-CD3 (zeige CD3E Antikörper)-activated CD8 (zeige CD8A Antikörper)(+) T cells in vitro and the anti-apoptotic effects of 4-1BB signaling on these cells.

  2. CD137 signaling activates the pro-angiogenic Smad1 (zeige SMAD1 Antikörper)/5 pathway, induces the phosphorylation of Smad1 (zeige SMAD1 Antikörper)/5 and nuclear translocation of p-Smad1 (zeige SMAD1 Antikörper)/5, which in turn promotes the expression and translocation of NFATc1 (zeige NFATC1 Antikörper). Blocking CD137 signaling with inhibitory anti-CD137 antibody could inhibit this activation and attenuated agonist anti-CD137 antibody-induced angiogenesis.

  3. the role of CD137-CRDI (cysteine rich domain I) in the binding of CD137-CD137L (zeige TNFSF9 Antikörper) was further investigated.

  4. Data indicate that anti-CD137 agonists can function as inhibitors of CD137L (zeige TNFSF9 Antikörper) signaling, resulting in the creation of tumor microenvironments unfavorable for tumor immune evasion.

  5. These studies reveal that the costimulatory effects of TLR1 (zeige TLR1 Antikörper)-TLR2 signaling in CD8 (zeige CD8A Antikörper)(+) T cells are in part mediated by 4-1BB and are important for mounting an effective antitumor immune response.

  6. This study discovers the 4-1BB pathway signaling enhances inflammatory response and promotes pulmonary fibrosis induced by crystalline silica.

  7. Constitutive interaction between 4-1BB and 4-1BBL (zeige TNFSF9 Antikörper) on murine LPS (zeige TLR4 Antikörper)-activated bone marrow dendritic cells masks detection of 4-1BBL (zeige TNFSF9 Antikörper) by TKS (zeige PTK6 Antikörper)-1 but not 19H3 antibody.

  8. results indicate that one important diabetogenic function of CD137 is to promote the expansion and accumulation of beta cell-autoreactive CD8 (zeige CD8A Antikörper) T cells, and in the absence of CD137 or its interaction with CD137 ligand, type 1 diabetes progression is suppressed

  9. High CD137 expression is associated with neoplasms.

  10. Ly6C, 4-1BB, and KLRG1 (zeige KLRG1 Antikörper) have roles in the activation of lamina propria lymphocytes in the small intestine in a mouse model of Crohn's disease

CD137 (TNFRSF9) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Genbezeichner und Symbole assoziert mit TNFRSF9

  • tumor necrosis factor receptor superfamily member 9 (TNFRSF9) Antikörper
  • TNF receptor superfamily member 9 (TNFRSF9) Antikörper
  • tumor necrosis factor receptor superfamily, member 9a (tnfrsf9a) Antikörper
  • tumor necrosis factor receptor superfamily, member 9 (Tnfrsf9) Antikörper
  • 4-1BB Antikörper
  • A930040I11Rik Antikörper
  • AA408498 Antikörper
  • AI325004 Antikörper
  • Cd137 Antikörper
  • CDw137 Antikörper
  • ILA Antikörper
  • Ly63 Antikörper
  • TNFRSF9 Antikörper
  • zgc:136557 Antikörper

Bezeichner auf Proteinebene für TNFRSF9

tumor necrosis factor receptor superfamily, member 9 , tumor necrosis factor receptor superfamily member 9 , 4-1BB ligand receptor , CD137 antigen , T cell antigen ILA , T-cell antigen 4-1BB homolog , T-cell antigen ILA , homolog of mouse 4-1BB , induced by lymphocyte activation (ILA) , interleukin-activated receptor, homolog of mouse Ly63 , receptor protein 4-1BB , T-cell antigen 4-1BB , secreted CD137 antigen

GENE ID SPEZIES
419365 Gallus gallus
520341 Bos taurus
608274 Canis lupus familiaris
678622 Danio rerio
708281 Macaca mulatta
746029 Pan troglodytes
100196937 Papio anubis
100348914 Oryctolagus cuniculus
3604 Homo sapiens
21942 Mus musculus
Ausgewählte Anbieter für anti-CD137 (TNFRSF9) Antikörper
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