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The protein encoded by TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. Zusätzlich bieten wir Ihnen TNFRSF13B Proteine (24) und TNFRSF13B Kits (20) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 179 products:
Mouse (Murine) Monoclonal TNFRSF13B Primary Antibody für FACS - ABIN4897628
Uslu, Coleman, Allman, Katsenelson, Bram, Alugupalli, Akkoyunlu: Impaired B cell receptor signaling is responsible for reduced TACI expression and function in X-linked immunodeficient mice. in Journal of immunology (Baltimore, Md. : 1950) 2014
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Human Monoclonal TNFRSF13B Primary Antibody für FACS - ABIN4896092
Tai, Li, Breitkreutz, Song, Neri, Catley, Podar, Hideshima, Chauhan, Raje, Schlossman, Richardson, Munshi, Anderson: Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment. in Cancer research 2006
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Mouse (Murine) Polyclonal TNFRSF13B Primary Antibody für BR, CyTOF - ABIN5012999
Kanswal, Katsenelson, Selvapandiyan, Bram, Akkoyunlu: Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL. in Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Monoclonal TNFRSF13B Primary Antibody für BR, CyTOF - ABIN5012998
Neri, Kumar, Fulciniti, Vallet, Chhetri, Mukherjee, Tai, Chauhan, Tassone, Venuta, Munshi, Hideshima, Anderson, Raje: Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model. in Clinical cancer research : an official journal of the American Association for Cancer Research 2007
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Human Polyclonal TNFRSF13B Primary Antibody für WB - ABIN2668579
Sakurai, Hase, Kanno, Kojima, Okumura, Kobata: TACI regulates IgA production by APRIL in collaboration with HSPG. in Blood 2007
Mouse (Murine) Monoclonal TNFRSF13B Primary Antibody für CyTOF, ELISA (Capture) - ABIN4900394
Matsumoto, Kobata, Odaka, Furukawa, Hirata, Yuki: BAFF aids generation of IgG anti-ganglioside antibodies in response to Campylobacter jejuni lipo-oligosaccharide. in Journal of neuroimmunology 2010
BAFF (zeige TNFSF13B Antikörper)-induced processing of BAFFR (zeige TNFRSF13C Antikörper) regulates BAFF (zeige TNFSF13B Antikörper)-mediated B cell responses in a TACI-dependent manner.
results suggest that TACI A181E heterozygosity results in TACI haploinsufficiency with increased susceptibility to pneumococcal infection
The expression levels of serum BAFF (zeige TNFSF13B Antikörper) and the three receptors (TACI, BCMA (zeige TNFRSF17 Antikörper) and BAFF-R (zeige TNFRSF13C Antikörper)) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.
11% of common variable immunodeficiency patients and 13% of antibody deficiency syndromes patients carried at least one mutated TNFRSF13B allele.
SNPs rs9514828 (BAFF (zeige TNFSF13B Antikörper)), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.
serum levels not associated with disease activity in MPO (zeige MPO Antikörper)-ANCA-associated renal vasculitis
In this review, we aim at giving an insight into the genetics underlying the CVID and particularly at outlining the role of TACI and its relative contribution to the development of CVID-like phenotypes in human.
TNFRSF13B hemizygosity does not recapitulate autoimmune features of common variable immune deficiency -associated C104R and A181E TNFRSF13B mutations, which likely encode dominant negative products, but instead reveals selective TACI haploinsufficiency at later stages of B-cell development.
Common variable immune d (zeige TNFSF13B Antikörper)eficiency patients with heterozygous mutations in TACI alleles increase susceptibility to autoimmune diseases.
The study demonstrated that there is a remarkable interindividual variability of TACI expression in chronic lymphocytic leukemia, although the majority of patients display low to undetectable TACI.
findings highlight a novel mechanism through which BAFF (zeige TNFSF13B Antikörper) promotes humoral autoimmunity via direct, TACI-dependent activation of transitional B cells
this study shows that increased TACI expression in B cells derived from non-obese diabetic mice contributes to the pathogenesis of type 1 diabetes NOD mice
splenic B cells from TACI-deficient (TACI- / -) mice were unable to secrete IL-10 (zeige IL10 Antikörper) following TLR stimulation, and TACI- / - mice had undetectable basal serum concentrations of IL-10 (zeige IL10 Antikörper).
Data show that production of autoantibodies in B cell-activating factor (zeige TNFSF13B Antikörper) of the TNF (zeige TNF Antikörper) family (BAFF (zeige TNFSF13B Antikörper)) is dependent on tumor necrosis factor (zeige TNF Antikörper) receptor superfamily, member 13b protein (TACI) expression by B cells.
Taci (-/-) mice and BAFF (zeige TNFSF13B Antikörper) transgenic mice both develop signs of human Systemic Lupus Erythematosus.
Elimination of B lymphocyte stimulator (zeige TNFSF13B Antikörper) receptor 3 (BR-3) and TACI inhibits the development of SLE in NZM mice.
TACI deficiency has a role in alternatively activated macrophage phenotype and susceptibility to Leishmania infection
Heteromers consisting of one BAFF (zeige TNFSF13B Antikörper) and two APRIL bind to receptor TACI, BCMA (zeige TNFRSF17 Antikörper) but not to BAFFR (zeige TNFRSF13C Antikörper).
Mice lacking TACI are able to clear Citrobacter rodentium, a model pathogen for severe human enteritis, more rapidly than did wild type mice.
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
transmembrane activator and CAML interactor
, tumor necrosis factor receptor 13B
, tumor necrosis factor receptor superfamily member 13B
, tumor necrosis factor receptor superfamily, member 13B
, transmembrane activator and calcium-modulating and cyclophilin ligand interactor