Tubulin Polymerization Promoting Protein Proteine (Tppp)

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. Zusätzlich bieten wir Ihnen Tppp Antikörper (94) und Tppp Kits (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Tppp 11076 O94811
Tppp 72948 Q7TQD2
Ratte Tppp Tppp 361466  
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Top Tppp Proteine auf antikoerper-online.de

Showing 7 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,541.00
Details
Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
Details

Tppp Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Mouse (Murine)

Weitere Proteine zu Tubulin Polymerization Promoting Protein (Tppp) Interaktionspartnern

Human Tubulin Polymerization Promoting Protein (Tppp) Interaktionspartner

  1. TPPP/p25 is co-enriched and co-localized with alpha-synuclein in brain inclusions of Parkinson's disease patients. Interaction of alpha-synuclein with various deletion mutants and fragments of TPPP/p25 were characterized.

  2. The objective of this paper is to highlight a critical point of a recently published Skoufias's paper in which the crucial role of the microtubules in TPPP/p25 dimerization leading to microtubule bundling was suggested.

  3. This study demonstrated that the AAV9-mediated p25 overexpression mouse model, which is a practical model exhibiting neurodegeneration-like pathological and behavioral changes.

  4. The knowledge accumulated so far underlines the key roles of the multifunctional TPPP/p25 in both physiological and diverse pathological processes, consequently its validation as drug target sorely needs a new innovative strategy that is briefly reviewed here.

  5. TPPP may have a role in poor prognosis in hepatocellular carcinoma

  6. the central folded domain of TPPP/p25 following binding to microtubules can drive s homotypic protein-protein interactions leading to bundled microtubules.

  7. Results reveal a link between p25 and BACE1 in Alzheimer disease (AD) brains and suggest that upregulated Cdk5 activation by p25 accelerates AD pathogenesis by enhancing BACE1 activity via phosphorylation.

  8. Epigenetic changes in TPPP, in combination with experiences of maltreatment, may confer risk for depression in children.

  9. suggest that the zinc as a specific divalent cation could be involved in the fine-tuning of the physiological TPPP/p25 level counteracting both the enrichment and the lack of this protein leading to distinct central nervous system diseases

  10. results suggest that ROCK regulates beta-catenin stability in cells via preventing TPPP1-mediated inhibition of HDAC6 activity, to reduce its acetylation and degradation via phosphorylation by CK1 and GSK3beta

  11. GSK3 promotes the mitochondrial translocation of p53, enabling its interaction with Bcl2 to allow Bax oligomerization and the subsequent release of cytochrome C.

  12. dual Rock and Cdk phosphorylation of Tppp1 inhibits its regulation of the cell cycle to increase cell proliferation

  13. The RhoA-ROCK-LIMK2-TPPP pathway controls metaphase spindle-orientation; TPPP colocalizes with LIMK2 at the mitotic spindle.

  14. Although serine-129 phosphorylation of alpha-synuclein facilitates TPPP-mediated alpha-SYN oligomerization, this modification does not seem to play an inevitable role in the early step of alpha-SYN oligomer formation in a cellular model of multiple system atrophy.

  15. The authors conclude that the modest structural changes that p25alpha undergoes can promote weak intermolecular contacts and that polyanions such as heparin play a central role in stabilizing these aggregates.

  16. Wnt induces the phosphorylation of LRP6 which consequently access the catalytic pocket of GSK3 as pseudo-substrates, thus directly blocking its activity against beta-catenin.

  17. GSK3 has a significant role in maintaining repression of growth factor-inducible genes during quiescence. CREB, NFkB and AP-1 mediate this regulation of gene expression by GSK-3.

  18. Data show that TPPP may work as a protective factor for cells against the damage effects of the accumulation of abnormal forms of PrPs, besides its function as an agent for dynamic stabilization of microtubular ultrastructures.

  19. Binding of Zn(2) bivalent cation to structurally disordered TPPP/p25 influences TPPP/p25-promoted tubulin polymerization and GTPase activity.

  20. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein.

Mouse (Murine) Tubulin Polymerization Promoting Protein (Tppp) Interaktionspartner

  1. The present study provides additional support for roles for TPPP in the etiology of depression following early adversity.

  2. These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination.

  3. LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly.

  4. A pathway was discovered by which p25 and cdk5 increases the amyloidogenic processing of amyloid precursor protein.

Tppp Protein Überblick

Protein Überblick

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Genbezeichner und Symbole assoziert mit Tppp

  • tubulin polymerization promoting protein (TPPP)
  • tubulin polymerization promoting protein (Tppp)
  • 2900041A09Rik Protein
  • AI849835 Protein
  • p24 Protein
  • p25 Protein
  • p25alpha Protein
  • RGD1310121 Protein
  • TPPP/p25 Protein
  • TPPP1 Protein

Bezeichner auf Proteinebene für Tppp

brain-specific protein p25 alpha , 25 kDa brain-specific protein , brain specific protein p25 alpha , glycogen synthase kinase 3 (GSK3) inhibitor p24 , p25-alpha , tubulin polymerization-promoting protein , tubulin polymerization promoting protein p25 alpha

GENE ID SPEZIES
420800 Gallus gallus
11076 Homo sapiens
488072 Canis lupus familiaris
100144410 Sus scrofa
280968 Bos taurus
72948 Mus musculus
361466 Rattus norvegicus
100734397 Cavia porcellus
101110090 Ovis aries
100358311 Oryctolagus cuniculus
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