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TRO encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium.
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Expression of trophinin and dipeptidyl peptidase IV (zeige DPP4 Antikörper) in endometrial co-culture in the presence of an embryo: A comparative immunocytochemical study.
report dual roles for trophinin in human cancers in terms of promoting malignancy in some tumor types and suppressing it in others
Trophinin induced apoptosis in endometrial epithelial cells through protein kinase C-delta (zeige PKCd Antikörper).
infertile women with endometriosis or unexplained infertility had significantly weakened trophinin expression in the endometrium in the mid-luteal phase
HCG (zeige CGA Antikörper) from the human embryo induces trophinin expression by maternal cells. Unique role of hCG (zeige CGA Antikörper) and trophinin in human embryo implantation, including the pathogenesis of ectopic pregnancy.
Maged3 expression is restricted to the central nervous system where it was mostly detected in postmitotic neurons
Fluorescence photobleaching of GFP-trophinin expressed in COS-1 cells showed the stable association of trophinin with the nuclear envelope.
trophinin-mediated cell adhesion functions as a molecular switch for trophectoderm activation in human embryo implantation
results suggest that trophinin promotes colorectal cancer invasion through a mechanism involving HMGB1 (zeige HMGB1 Antikörper)/RAGE (zeige AGER Antikörper)
Trophinin functions as an adhesion molecule (zeige NCAM1 Antikörper) on the cell surface and as a molecular switch for trophoblast activation in the cytoplasm.
The expression of trophinin in the mouse sperm tail causes a significant increase in sperm motility.
Targeted disruption of the trophinin gene in the mouse showed a partial embryonic lethality in a 129/SvJ background
This gene encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. The encoded protein participates in cell signalling during embryo implantation, and may also be involved in cancer formation. This gene is located near several other closely related genes on chromosome X. Alternative splicing results in multiple transcript variants.
MAGE superfamily protein
, MAGE-D3 antigen
, melanoma antigen, family D, 3
, necdin and trophinin like