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TRO encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. Zusätzlich bieten wir Ihnen TRO Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Expression of trophinin and dipeptidyl peptidase IV in endometrial co-culture in the presence of an embryo: A comparative immunocytochemical study.
report dual roles for trophinin in human cancers in terms of promoting malignancy in some tumor types and suppressing it in others
Trophinin induced apoptosis in endometrial epithelial cells through protein kinase C-delta.
infertile women with endometriosis or unexplained infertility had significantly weakened trophinin expression in the endometrium in the mid-luteal phase
HCG from the human embryo induces trophinin expression by maternal cells. Unique role of hCG and trophinin in human embryo implantation, including the pathogenesis of ectopic pregnancy.
Maged3 expression is restricted to the central nervous system where it was mostly detected in postmitotic neurons
Fluorescence photobleaching of GFP-trophinin expressed in COS-1 cells showed the stable association of trophinin with the nuclear envelope.
trophinin-mediated cell adhesion functions as a molecular switch for trophectoderm activation in human embryo implantation
results suggest that trophinin promotes colorectal cancer invasion through a mechanism involving HMGB1/RAGE
Trophinin functions as an adhesion molecule on the cell surface and as a molecular switch for trophoblast activation in the cytoplasm.
When magphinin-gamma was expressed in NIH3T3 cells, cells underwent G1 arrest. These results suggest that human magphinin-gamma inhibits cell cycle progression through nuclear activity.
TROPHONIN (TRO) is among the genes most downregulated by RAS. TRO expression is higher in cisplatin-sensitive cancer cell lines and positively correlates with prognoses in ovarian cancers.
results provide a mechanism for trophinin-mediated adhesion of human blastocyst to endometrium by a spatially and temporally restricted paracrine effect of hCG derived from the blastocyst
Overexpression of trophinin leads to a more invasive phenotype and metastatic potential in human gallbladder cancer transfected into nude mice.
The expression of trophinin in the mouse sperm tail causes a significant increase in sperm motility.
Targeted disruption of the trophinin gene in the mouse showed a partial embryonic lethality in a 129/SvJ background
This gene encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. The encoded protein participates in cell signalling during embryo implantation, and may also be involved in cancer formation. This gene is located near several other closely related genes on chromosome X. Alternative splicing results in multiple transcript variants.
MAGE superfamily protein
, MAGE-D3 antigen
, melanoma antigen, family D, 3
, necdin and trophinin like