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TRIM45 encodes a member of the tripartite motif family.
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Human Polyclonal TRIM45 Primary Antibody für WB - ABIN4890143
Zhang, Zhang, Cui, Ou, Han, Qin, Zhi, Wang: TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination. in Cell death & disease 2017
These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 (zeige TP53 Antikörper) in glioma.
The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway.
These findings suggest that TRIM45 acts as a repressor for the NF-kappaB (zeige NFKB1 Antikörper) signal and regulates cell growth.
TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase (zeige MAPK1 Antikörper) signaling pathway
This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.
tripartite motif-containing 45
, tripartite motif-containing protein 45-like
, tripartite motif containing 45
, ring finger protein 99
, tripartite motif-containing protein 45
, tripartite motif protein 45