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May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. Zusätzlich bieten wir Ihnen Trichoplein, Keratin Filament Binding Proteine (5) und Trichoplein, Keratin Filament Binding Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal TCHP Primary Antibody für WB - ABIN2788476
Wong, Vaz, Lee, Zhao, Luo, Archer, Preiss, Tanavde, Vardy: Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation. in PLoS ONE 2016
Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.
These findings underscore the complexity of PGC-1alpha-mediated mitochondrial homeostasis and establish mitostatin as a key regulator of tumor cell mitophagy and angiostasis.
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
Trichoplein/mitostatin is a new regulator of mitochondria-endoplasmic reticulum juxtaposition.
MITOSTATIN was found within a 3.2-kb transcript for an approximately 62 kDa mitochondrial protein with tumor suppressor activity. It inhibits cell growth, is proapoptotic and downregulates Hsp27.
trichoplein is a keratin 8/18-binding protein that may be involved in the organization of the apical network of keratin filaments and desmosomes in simple epithelial cells
May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity).
trichoplein, keratin filament binding
, mitochondrial protein with oncostatic activity
, trichoplein keratin filament-binding protein
, tumor suppressor protein