anti-Transmembrane Protein 67 (TMEM67) Antikörper

The protein encoded by TMEM67 localizes to the primary cilium and to the plasma membrane. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TMEM67 91147 Q5HYA8
TMEM67 329795 Q8BR76
TMEM67 313067  
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Top anti-TMEM67 Antikörper auf antikoerper-online.de

Showing 10 out of 24 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$351.11
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Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts from 293, using MKS3 antibody. Lane 1 was treated with the blocking peptide. Western blot analysis of extracts from human kidney, using MKS3 antibody. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert WB Western Blot: Meckelin Antibody [NBP1-32896] - Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE; antibody diluted at 1:1000. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$516.98
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Maus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$355.34
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
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Human Kaninchen Unkonjugiert EIA, IHC (fro), WB Immunohistochemical staining of kideny tissue sections with AP55072SU-N Immunodetection of Mckerlin (120 kDa) in whole cell extracts of HEK293 cells using this product 0.2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
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Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using TMEM67 antibody (ABIN6293383) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min. 50 μL Anmelden zum Anzeigen 16 Days
$308.12
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$429.00
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Weitere Antikörper gegen TMEM67 Interaktionspartner

Zebrafish Transmembrane Protein 67 (TMEM67) Interaktionspartner

  1. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.

Human Transmembrane Protein 67 (TMEM67) Interaktionspartner

  1. Kidney disease occurs in up to one third of patients with Joubert syndrome, most commonly in those with mutations in CEP290, TMEM67, and AHI1.

  2. The authors results suggest that Asn242Ser in TMEM67 is a founder mutation in the Iranian population, which might explain a significant proportion of JS cases from eastern Iran.

  3. Low expression of TMEM67 is associated with lymph node metastasis in urothelial carcinoma of the bladder.

  4. Importantly, one Japanese and one Omani families carried compound biallelic mutations in two distinct genes (TMEM67/RPGRIP1L and TMEM138/BBS1, respectively).

  5. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.

  6. mutation analysis of TMEM67 in Joubert syndrome and related disorders cases and Meckel syndrome fetuses; identification of 20 novel mutations; review of published mutations and discussion of genotype-phenotype correlates

  7. Mutations in MKS3 are responsible for the majority of COACH syndrome, with minor contributions from CC2D2A and RPGRIP1L.

  8. Data show that knockdown of MKS3 inhibited degradation of mutant SP-C.

  9. mapping to chromosome 8 and possible role in Meckel-Gruber syndrome

  10. Positional cloning of the Wpk gene suggested a MKS3 candidate gene, TMEM67, for which we identified pathogenic mutations for five MKS3-linked consanguineous families.

  11. identified MKS3 mutations in four patients with JS, thus defining MKS3 as the sixth JS locus (JBTS6)

  12. The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.

  13. Study concluded that MKS1 and MKS3 account for the majority of Meckel-Gruber syndrome; polydactyly is usually found in MKS1 but rare in MKS3; cases with no, or milder, CNS phenotypes were only found in MKS3.

  14. genotyping of MKS1 & MKS3 genes in a large, multiethnic cohort of 120 independent cases of Meckel syndrome; first results indicate that the MKS1 & MKS3 genes are each responsible for about 7% of MKS cases with various mutations in different populations

  15. Mutations in MKS3 is associated with Bardet-Biedl syndrome

  16. Analysis of MKS3 in 14 COACH families identified mutations in 8 (57%).

  17. Missense mutations within the MKS3 gene are associated with nephronophthisis with liver fibrosis.

  18. Kidney tissue and cells from MKS1 and MKS3 patients showed defects in centrosome and cilia number, including multi-ciliated respiratory-like epithelia, and longer cilia.

Mouse (Murine) Transmembrane Protein 67 (TMEM67) Interaktionspartner

  1. Multi-organ developmental abnormalities in the Tmem67(tm1Dgen/H1) knockout mouse that closely resemble those seen in Wnt5a and Ror2 knockout mice.

  2. Meckelin is expressed in mESCs and localized at the primary cilium. Meckelin depletion impairs neural differentiation of mESCs.

  3. TMEM67 mutations cause PKD through ERK- and JNK-dependent signalling pathways, which may provide novel insight into the therapy of polycystic kidney diseases.

  4. The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.

  5. The Tmem67 knockout mouse line is unique in modelling the variable expressivity of phenotypes in Meckel-Gruber syndrome and Joubert syndrome.

  6. Meckelin is a component of ciliary and cell membranes and is encoded by Tmem67 (Mks3).

TMEM67 Antigen-Profil

Protein Überblick

The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).

Genbezeichner und Symbole assoziert mit TMEM67

  • transmembrane protein 67 (TMEM67) Antikörper
  • transmembrane protein 67 (tmem67) Antikörper
  • transmembrane protein 67 (Tmem67) Antikörper
  • 5330408M12Rik Antikörper
  • b2b1163.1Clo Antikörper
  • b2b1291.1Clo Antikörper
  • B230117O07 Antikörper
  • JBTS6 Antikörper
  • MECKELIN Antikörper
  • MKS3 Antikörper
  • NPHP11 Antikörper
  • TNEM67 Antikörper
  • Wpk Antikörper

Bezeichner auf Proteinebene für TMEM67

transmembrane protein 67 , mks3 , meckelin-like , Meckelin-like , Meckelin , meckel syndrome type 3 protein , meckel syndrome type 3 protein homolog , Meckel syndrome type 3 protein homolog , Wistar polycystic kidney

GENE ID SPEZIES
420224 Gallus gallus
472937 Pan troglodytes
487049 Canis lupus familiaris
572194 Danio rerio
698631 Macaca mulatta
100029719 Monodelphis domestica
100051660 Equus caballus
100373519 Saccoglossus kowalevskii
100413391 Callithrix jacchus
100460277 Pongo abelii
100480482 Ailuropoda melanoleuca
100492945 Xenopus (Silurana) tropicalis
100559654 Anolis carolinensis
91147 Homo sapiens
329795 Mus musculus
313067 Rattus norvegicus
Ausgewählte Anbieter für anti-TMEM67 (TMEM67) Antikörper
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