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TMPRSS13 encodes a member of the type II transmembrane serine protease family.
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The data provide novel insight into the cellular properties of TMPRSS13 and highlight phosphorylation of TMPRSS13 as a novel post-translational modification of this TTSP (zeige TMPRSS11E Antikörper) family member and potentially other members of this family of proteases.
study demonstrates that two cellular serine proteases, DESC1 (zeige TMPRSS11E Antikörper) and MSPL, activate influenza viruses and emerging coronaviruses in cell culture and, because of their expression in human lung tissue, might promote viral spread in the infected host
results suggest that TMPRSS13 functions as an HGF (zeige HGF Antikörper)-converting protease, the activity of which may be regulated by HAI-1 (zeige SPINT1 Antikörper)
The authors report that serine proteases, MSPL and its splice variant TMPRSS13, are novel candidates for proteases processing HA proteins of highly pathogenic avian influenza (HPAI) viruses.
cloning of MSPL/TMPRSS13, which may play roles in the proteolytic processing of prohormones, precursors of growth factors, and also play roles in the pathogenicity of many viruses and bacteria in vivo
Data (including data from studies in knockout mice) suggest Tmprss13 plays role in stratum corneum formation and transepidermal fluid balance; Tmprss13 expression is high in skin and epithelia of mouth, upper digestive tract, and urinary bladder.
This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
transmembrane protease serine 13
, transmembrane protease, serine 13
, membrane-type mosaic serine protease
, transmembrane protease, serine 11