anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) Antikörper

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Zusätzlich bieten wir Ihnen TRPM8 Proteine (10) und TRPM8 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRPM8 79054 Q7Z2W7
TRPM8 171382 Q8R4D5
TRPM8 171384 Q8R455
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Top anti-TRPM8 Antikörper auf antikoerper-online.de

Showing 10 out of 170 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-TRPM8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  ACHN cell lysate Immunohistochemistry with Prostate tissue at an antibody concentration of 5µg/ml using anti-TRPM8 antibody (ARP35357_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: TRPM8 Sample Type: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Anti- TRPM8 Picoband antibody, Western blottingAll lanes: Anti TRPM8  at 0.5ug/ml  Lane 1: HELA Whole Cell Lysate at 40ug  Lane 2: 22RV1 Whole Cell Lysate at 40ug  Lane 3: SW620 Whole Cell Lysate at 40ug  Lane 4: A549 Whole Cell Lysate at 40ug  Lane 5: A431 Whole Cell Lysate at 40ug Predicted bind size: 127KD Observed bind size: 127KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of TRPM8 expression in A549 (A), PC3 (B), NIH3T3 (C), H9C2 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB TRPM8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TRPM8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. TRPM8 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the TRPM8 antibody detected the TRPM8 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Fruchtfliege Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, ELISA, WB Detection of Trp-p8 in transfected Cos cell lysate using ABIN152287 (1:750). Prostate cancer: Formalin-Fixed Paraffin-Embedded (FFPE) 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$556.31
Details
Ratte Kaninchen Unkonjugiert IHC, WB IF on rat olfactory bulb using Rabbit antibody to rat TRPM8: whole serum at 1 : 500 dilution and DAPI counterstained. IF on rat olfactory bulb using Rabbit antibody to rat TRPM8: whole serum at 1 : 500 dilution and DAPI counterstained appearing in blue. 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-TRPM8 antibody  ABIN1049435 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Meerschweinchen Kaninchen Unkonjugiert IHC, IHC (p) Anti-TRPM8 antibody  ABIN1049436 IHC staining of human prostate carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-TRPM8 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB Anti-TRPM8 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959036 concentration 5 ug/ml. Anti-TRPM8 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details

TRPM8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-TRPM8 Antikörper

  1. Fruit Fly (Drosophila melanogaster) Polyclonal TRPM8 Primary Antibody für ICC, IHC (fro) - ABIN152287 : Peabody, Pohl, Diao, Vreede, Sandstrom, Wang, Zelensky, White: Characterization of the decision network for wing expansion in Drosophila using targeted expression of the TRPM8 channel. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TRPM8 Primary Antibody für ELISA - ABIN451742 : Dhaka, Murray, Mathur, Earley, Petrus, Patapoutian: TRPM8 is required for cold sensation in mice. in Neuron 2007 (PubMed)

  3. Human Polyclonal TRPM8 Primary Antibody für ICC, IF - ABIN4362970 : Wang, Yu, Yan, Lei, Chai, Jiang, Yuan, Xing, Du: TRPM8 in the negative regulation of TNFα expression during cold stress. in Scientific reports 2017 (PubMed)

Weitere Antikörper gegen TRPM8 Interaktionspartner

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) Interaktionspartner

  1. The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) Interaktionspartner

  1. Data show evidence of recent local ambient temperature adaptation on the cation channel (zeige TRPV1 Antikörper) TRPM8.

  2. TRPM8 levels may be elevated in basal breast cancers, however, TRPM8 expression appears to be lost in many breast cancer cell lines

  3. In this study, we identify non-channel cytoplasmic small TRPM8 isoforms as putative regulator of PCa (zeige FLVCR1 Antikörper) cell death

  4. Praziquantel is a relatively potent and selective partial agonist of the mammalian and avian cold and menthol receptor TRPM8.

  5. The TRPM8 transient receptor potential channel.

  6. our results indicate that enhanced TRPM8 hydrolysis in prostate cancer could present an adaptation mechanism, sustained via bypassing testosterone-induced rapid Ca2 (zeige CA2 Antikörper)+ uptake through TRPM8, thus, diminishing the rates of apoptosis

  7. Suggest a novel, pore-independent molecular mechanism by which endogenous TRPM8 expression inhibits Rap1 (zeige RABGEF1 Antikörper) GTPase (zeige RACGAP1 Antikörper) and thus plays a critical role in the behavior of vascular endothelial cells by inhibiting migration.

  8. in this study, the glycosylation status of the TRPM8 channel was shown to affect cell proliferation, cell migration, and calcium uptake. TRPM8 expressed in the membrane of the Panc-1 pancreatic tumoral cell line is non-glycosylated, whereas human embryonic kidney cells transfected with human TRPM8 overexpress a glycosylated protein.

  9. This study demonstrates that TRPM8 (cold receptor) is present in nasal epithelium. When it is activated by moderate cooling at 24 degrees C or menthol, TRPM8 induces the secretion of mucin (zeige SLC13A2 Antikörper). This study determines that TRPM8 channels are important regulators of mucin (zeige SLC13A2 Antikörper) production. Therefore, TRPM8 antagonists could be used for the treatment of refractory rhinitis.

  10. This study suggests that the TRPM8 sensor is a key determinant of germ cell fate under hypothermic stimulation.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) Interaktionspartner

  1. These results suggest that TRPM8 expressed in tissues apart from cutaneous sensory nerves are involved in autonomic thermoregulation response.

  2. Since disruption of the clock machinery has been associated with many metabolic disorders, the pharmacological modulation of TRPM8 channel may become a promising therapeutic target to counterbalance weight gain, through increased thermogenesis, energy expenditure, and clock gene activation.

  3. These results suggest that TRPV4, TRPV3 and TRPM8 proteins, but not their ion channel activities are necessary for the induction of CIPs at 32 degrees C. Identification of proteins that differentially interact with these TRP channels at 37 degrees C and 32 degrees C would help elucidate the underlying mechanisms of CIP induction by hypothermia.

  4. Praziquantel is a relatively potent and selective partial agonist of the mammalian and avian cold and menthol receptor TRPM8.

  5. These results taken together with other reports suggest that TRPM8 containing sensory neurons are environmental cooling detectors that may be nociceptive or non-nociceptive depending on the sensitivity of individual fibers to different combinations of stimulus modalities.

  6. TRPM8 activation by dietary menthol improves energy metabolism and exercise endurance, which are likely driven by TRPM8-mediated Ca2 (zeige CA2 Antikörper)+-dependent upregulation of PGC1alpha and its target genes involved in the mitochondrial function.

  7. TRPM8 in macrophages determines pro- or anti-inflammatory actions by regulating tumor necrosis factor-alpha (zeige TNF Antikörper) and interleukin-10 (zeige IL10 Antikörper) production. These findings suggest novel TRPM8-based options for immunomodulatory intervention.

  8. Here the authors show that AITC (allyl isothiocyanate; mustard oil) and menthol represent two distinct types of ligands at the mammalian cold sensor TRPM8.

  9. The results of this study show that chronic morphine upregulates TRPM8 channels, which is in contrast with the previous finding that acute morphine triggers TRPM8 internalization.

  10. data suggest that sex differences in the functioning of Ih and Ik in TRPM8 expressing primary afferent neurons leads to differences in cool temperature sensitivity

TRPM8 Antigen-Profil

Protein Überblick

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.

Genbezeichner und Symbole assoziert mit TRPM8

  • transient receptor potential cation channel subfamily M member 8 (TRPM8) Antikörper
  • transient receptor potential cation channel subfamily M member 8b L homeolog (trpm8b.L) Antikörper
  • transient receptor potential cation channel subfamily M member 8 (Trpm8) Antikörper
  • transient receptor potential cation channel, subfamily M, member 8 (Trpm8) Antikörper
  • transient receptor potential cation channel, subfamily M, member 8 (TRPM8) Antikörper
  • CMR1 Antikörper
  • LTrpC-6 Antikörper
  • LTRPC6 Antikörper
  • Trp-p8 Antikörper
  • TRPM8 Antikörper
  • trpm8b Antikörper
  • TRPP8 Antikörper

Bezeichner auf Proteinebene für TRPM8

transient receptor potential cation channel, subfamily M, member 8 , transient receptor potential cation channel subfamily M member 8b , transient receptor potential cation channel subfamily M member 8 , transient potential cation channel subfamily M member 8 , LTrpC-6 , long transient receptor potential channel 6 , short form of the TRPM8 cationic channel , transient receptor potential p8 , transient receptor potential subfamily M member 8 , trp-p8 , TRP ion channel TRPM8 , transient receptor potential-p8 , cold menthol receptor 1 , cold/menthol receptor 1 , menthol receptor , transient receptor potential M8 protein , transient receptor potential cation channel, subfamily M, member 8 (predicted), 3 prime , transient receptor potential cation channel, subfamily M, member 8 (predicted), 5 prime

GENE ID SPEZIES
100137386 Papio anubis
100302012 Xenopus laevis
100337634 Cavia porcellus
79054 Homo sapiens
171382 Mus musculus
171384 Rattus norvegicus
424025 Gallus gallus
486170 Canis lupus familiaris
541151 Bos taurus
100328692 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-TRPM8 (TRPM8) Antikörper
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