Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) ELISA Kits

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. Zusätzlich bieten wir Ihnen TGFBR2 Antikörper (235) und TGFBR2 Proteine (38) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TGFBR2 7048 P37173
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
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Top TGFBR2 ELISA Kits auf antikoerper-online.de

Showing 8 out of 46 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 10pg/mL 15.6-1000 pg/mL Human TGFBR2 PicoKine ELISA Kit standard curve 96 Tests Anmelden zum Anzeigen 4 bis 6 Tage
€326.55
Details
Maus 0.112 ng/mL 0.31-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
€670.70
Details
Ratte 0.129 ng/mL 0.31-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
€707.96
Details
Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
€336.28
Details
Human 2 pg/mL 2.1 pg/mL - 500 pg/mL   96 Tests Anmelden zum Anzeigen 5 bis 8 Tage
€610.28
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Hamster
  96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
€716.85
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
€911.15
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
€969.56
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Am meisten referenzierte TGFBR2 ELISA Kits

  1. Human TGFBR2 ELISA Kit für Sandwich ELISA - ABIN418671 : Zhang, Chen, Chen, Meng, Xiong, Liu, Jin, Tao, Wu, Sun: TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. in Scientific reports 2016 (PubMed)

Weitere ELISA Kits für TGFBR2 Interaktionspartner

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Interaktionspartner

  1. Data show that activated proto-oncogene protein Akt (AKT) directly phosphorylates Fas associated factor 1 (FAF1) reduces FAF1 at the plasma membrane and results in an increase in TGF-beta type II receptor (TbetaRII) at the cell surface.

  2. our study verified the correlations of TGFBR2 and hTERT in vitro and suggests that TGFBR2 and hTERT expression may be used as a diagnostic biomarker for cervical dysplasia and carcinoma.

  3. TGFBR2 Polymorphisms Are Associated with Colorectal Cancer in Patients with Lynch Syndrome.

  4. This study has confirmed or corrected the clinical diagnosis, and enlarged the mutation spectrum of FBN1 and TGFBR2 and confirmed that parental mosaicism may be the cause of the varied phenotypic expression of these connective tissue disorders.The results should be helpful for prenatal diagnosis and genetic counseling.

  5. the restoration of TGFBR2 in miR-204 overexpression Gastric cancer (GC) cells, which recovered resistance to 5-FU treatments compared with miR-204 overexpression GC cells.

  6. MiR-9-5p promotes the proliferation, metastasis and invasion of non-small cell lung cancer cells by down-regulating TGFBR2 expression.

  7. Microarray-based analyses revealed that the expression of miR-20b was significantly increased, whereas TGFBR2 and MYC were significantly downregulated and upregulated, respectively, in all ES cells compared to their expression in human mesenchymal stem cells (hMSCs).

  8. this study provides evidence that TGFBR2 rs6785358 polymorphism might be associated with the risk of hypospadias.

  9. TGFBR1/2 genetic variants (in particular when evaluated as a burden by score) might play a role in modulating the severity of cardiovascular manifestation in Marfan syndrome.

  10. Down-regulation of TGF-beta RII was found in the invasive non-functioning pituitary adenomas compared to noninvasive ones.

  11. findings reveal a novel role for miR-204/ANGPT1/TGFbetaR2 axis in tumor angiogenesis. We propose that therapeutic manipulation of miR-204 levels may represent a promising approach in breast cancer.

  12. Proteotoxic stress suppressed TGFb-induced EMT through downregulation of TGFbR-II and subsequent blockade of Smad2, ERK1/2, and FAK activation.

  13. High TGFBR2 expression is associated with small cell lung cancer.

  14. expression induced by IL-6 in keratinocytes

  15. hsa-miR-1193 may be involved in sporadic colorectal cancer tumourigenesis at least in part by suppression of TGFBR2, and the A allele of rs11466537 disturbed the regulation of hsa-miR-1193 on TGFBR2.

  16. DZNep induced miR-202-5p to target both TGFbeta receptors, TGFBR1 and TGFBR2...transfection of anti-miRNAs against miR-202-5p resulted in increased TGFBR1 and TGFBR2 protein expressions and induced EMT characteristics in these cells. In stellate pancreatic cells, miR-202 overexpression slowed growth as well as reduced stromal extracellular membrane matrix protein expression

  17. Results show that TGFbR2 expression decreases in human gastric cancer (GC) tissue specimens and indicate that the expression of TGFbR2 is mainly dependent on post-transcriptional regulators in GC through miR-155 binding to the 3'-UTR of its mRNA.

  18. miR-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2 via the TGF-beta/SMAD signaling pathway.

  19. This study demonstrated that Increased Transforming Growth Factor beta2 in the Neocortex of Alzheimer's Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Abeta42 Load.

  20. Data indicate the most significant gene level association seen with transforming growth factor beta receptor 2 (TGFBR2) and clear cell epithelial ovarian cancer (EOC).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Interaktionspartner

  1. Taken together, these results indicate that eIF6 may be involved in external mechanical force-mediated murine dermal fibroblast function at least partly through the TGF-beta1/TGFBR1/TGFBR2 pathway.

  2. miR-130a-3p might play a critical role in negatively regulating hepatic stellate cell activation and proliferation in the progression of nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2 via the TGF-beta/SMAD signaling pathway.

  3. the molecular actions of TGFBR2 result in both SMAD4-dependent constraint of proliferation and SMAD4-independent activation of apoptosis

  4. altered Tgfbeta signaling in cultured mouse and human enteroids supports further the in vivo data and reveals a critical role for Tgfbeta signaling in generating precursor secretory cells. Overall, our data reveal a key role for Tgfbeta signaling in regulating ISCs clonal dynamics and differentiation, with implications for cancer, tissue regeneration, and inflammation.

  5. In young Fbn1(C1039G/+) mice, aortopathy develops in the absence of detectable alterations in smooth muscle cell (SMC) TGF-beta signaling. Loss of physiologic SMC TGF-beta signaling exacerbates MFS-associated aortopathy. Our data support a protective role for SMC TGF-beta signaling during early development of MFS-associated aortopathy.

  6. The present study demonstrates that TGFbeta responsiveness in the myeloid compartment is critical in controlling autoimmune encephalomyelitis, and that its specific deletion in monocyte-derived dendritic cells causes severe experimental autoimmune encephalomyelitis without remission.

  7. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 signaling and that decreased bone volume in Osx-Cre;Tgfbr2(fl/fl) mice is likely due to fewer mature osteoblasts.

  8. The authors identify ELMO1 as a novel target of TGFbeta signaling and show that restoration of Tgfbr2 results in a complete block of ELMO1 in vivo. Knocking down Elmo1 impairs metastasis of carcinoma cells to the lung, thereby providing insights into the mechanisms of progression of Tgfbr2-deficient invasive transition zone squamous cell carcinoma.

  9. removing TGF-b type II receptor in DA neurons also disrupts the balance in TGF-b1 expression in DA neurons and neighboring GABAergic neurons, which increases inhibitory input, reduces excitatory synaptic input, and alters phasic firing patterns in DA neurons

  10. PAR1 in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.

  11. Cell-intrinsic TGFbeta-RII signaling limits CD4 T cell proliferation but not prototypical T helper subset differentiation early after chronic lymphocytic choriomeningitis virus infection.

  12. These results suggest that DMSO, a fusogenic substance, enhances TGF-beta activity presumably by inducing fusion of cytoplasmic vesicles (containing TbetaR-II) and the plasma membrane, resulting in increased localization of TbetaR-II to non-lipid raft microdomains where canonical signaling occurs.

  13. USP11 may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta-1 signaling.

  14. both GDF-15 and TGF-beta1 counteract chemokine-induced integrin activation on neutrophils via the ALK-5/TGF-betaRII heterodimer.

  15. Knockout of the TGFbeta receptor in proopiomelanocortin neurons counteracts the hypertensive effect of not only TGFbeta but also mtDNA excess, while the hypertensive action of central mtDNA can be blocked pharmacologically by a TGFbeta receptor antagonist or genetically by TGFbeta receptor knockout.

  16. Postnatal disruption of Tgfbr2 gene compromises extracellular matrix properties and promotes aortic dissection, which can be prevented by rapamycin treatment.

  17. Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc, promoting colorectal cancer cell proliferation.

  18. In the presence of gadolinium and antibeta1 integrin antibody, collagen regulated the expression levels of Tgfbr1, Tgfbr2 and Smad2/3, but did not alter the phosphorylation of p38, ERK1/2 or JNK.

  19. Epithelial TGFbeta signaling via TGFBR2 does not contribute to the development of liver fibrosis or formation of hepatocellular carcinomas in mice, but restricts cholangiocyte proliferation to prevent cholangiocarcinoma development.

  20. The removal of Tgfbr2 and treatment with losartan both delayed the progression of articular cartilage degeneration induced by medial meniscus (DMM) compared with control littermates.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Interaktionspartner

  1. found in binucleate cells of placenta

  2. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta responsiveness.

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Interaktionspartner

  1. Expression of microRNA miR-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta receptor 2 (TGFbeta-R2) and SMAD5.

Zebrafish Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Interaktionspartner

  1. The zebrafish T beta RII cDNA sequence is the first to be reported from a fish species, and it shows a high level of conservation at the kinase domain. mRNA expression of TGF-beta 1, T beta RII.

TGFBR2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Genbezeichner und Symbole assoziert mit TGFBR2

  • transforming growth factor beta receptor 2 (TGFBR2) Antikörper
  • transforming growth factor, beta receptor II (Tgfbr2) Antikörper
  • transforming growth factor, beta receptor 2 (Tgfbr2) Antikörper
  • transforming growth factor beta receptor 2b (tgfbr2b) Antikörper
  • transforming growth factor beta receptor 2 (Tgfbr2) Antikörper
  • 1110020H15Rik Antikörper
  • AAT3 Antikörper
  • AU042018 Antikörper
  • cb537 Antikörper
  • DNIIR Antikörper
  • FAA3 Antikörper
  • LDS1B Antikörper
  • LDS2B Antikörper
  • MFS2 Antikörper
  • RIIC Antikörper
  • RIIDN Antikörper
  • TAAD2 Antikörper
  • TBETA-RII Antikörper
  • TbetaR-II Antikörper
  • TbetaRII Antikörper
  • TBR-II Antikörper
  • TGF-beta 2 Antikörper
  • TGFbeta-RII Antikörper
  • tgfbr2 Antikörper
  • Tgfbr2T Antikörper
  • TGFBRII Antikörper
  • TGFR-2 Antikörper
  • wu:fj05c10 Antikörper
  • zgc:110498 Antikörper

Bezeichner auf Proteinebene für TGFBR2

TGF-beta receptor type II , TGF-beta receptor type-2 , TGF-beta type II receptor , TGFR-2 , tbetaR-II , transforming growth factor-beta receptor type II , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC , TGF-beta receptor II , transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF beta receptor type II , TGF-beta receptor type-2-like , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , TGF-beta receptor 2 , transforming growth factor-beta receptor 2

GENE ID SPEZIES
396399 Gallus gallus
7048 Homo sapiens
21813 Mus musculus
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
535376 Bos taurus
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
81810 Rattus norvegicus
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
30739 Danio rerio
100718284 Cavia porcellus
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