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TFPI2 encodes a member of the Kunitz-type serine proteinase inhibitor family. Zusätzlich bieten wir Ihnen TFPI2 Antikörper (133) und TFPI2 Kits (41) und viele weitere Produktgruppen zu diesem Protein an.
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Tissue factor pathway Inhibitor 2 potencies differ between antifibrinolytic agents against human and mouse enzymes plasmin (zeige PLG Proteine), factor XIa, and kallikrein (zeige KLK4 Proteine)
estrogen induced TFPI-2 expression in MCF7 cells is mediated by ERalpha (zeige ESR1 Proteine) and also by the action of LSD1 (zeige KDM1A Proteine).
TFPI2 hypermethylation is associated with colorectal cancer.
our research indicated that miR (zeige MLXIP Proteine)-130a functions as an oncogene (zeige RAB1A Proteine) by targeting TFPI2, miR (zeige MLXIP Proteine)-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK (zeige PTK2 Proteine)/PI3K (zeige PIK3CA Proteine)/Rac1/mdm2 (zeige MDM2 Proteine) pathway
TFPI-2 expression was decreased in bladder cancer. TFPI-2 expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.
TFPI2 is a useful serum biomarker for preoperative clinical diagnosis of CCC.
This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.
Over-expression of TFPI-2 and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.
Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (zeige PRSS3 Proteine) accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.
Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.
Tissue factor pathway Inhibitor 2 potencies differ between antifibrinolytic agents against human and mouse enzymes plasmin (zeige PLG Proteine), factor XIa, and kallikrein (zeige KLK1 Proteine)
A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.
Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.
Bovine TFPI2 was compared to mouse TFPI2.
human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species
Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.
Deficiency for the histone methyltransferase EHMT2 (zeige EHMT2 Proteine) or for the Polycomb group protein EED (zeige EED Proteine), leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.
Dynamic changes of Tfpi2 associated with Il-1beta (zeige IL1B Proteine) and Tnf-alpha (zeige TNF Proteine) in the development of acute lung injury are reported.
Bovine TFPI2 was cloned and its expression and characterization determined.
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
tissue factor pathway inhibitor 2
, tissue factor pathway inhibitor-2
, Tissue factor pathway inhibitor 2
, placental protein 5
, retinal pigment epithelium cell factor 1