TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) ELISA Kits

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Zusätzlich bieten wir Ihnen TIFA Antikörper (39) und TIFA Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human TIFA TIFA 92610 Q96CG3
Anti-Maus TIFA TIFA 211550 Q793I8
Anti-Ratte TIFA TIFA 310877 Q5XIB9
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Weitere ELISA Kits für TIFA Interaktionspartner

Human TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) Interaktionspartner

  1. we report that Aurora A (zeige AURKA ELISA Kits) is essential for phosphorylation of the TRAF-interacting protein (zeige TANK ELISA Kits) TIFA (zeige IL22 ELISA Kits)

  2. This study reports the crystal structures of TIFA (zeige IL22 ELISA Kits) (residues 1-150, with the unstructured C-terminal tail truncated) and its complex with the N-terminal phosphothreonine9 peptide (residues 1-15).

  3. an innate immune signaling axis, mediated by phosphorylation-dependent oligomerization of the TRAF-interacting protein with forkhead-associated domain (TIFA) that is triggered by heptose-1,7-bisphosphate.

  4. identify a novel threonine phosphorylation site on TIFA (zeige IL22 ELISA Kits) and show that this phosphorylated threonine binds with the FHA (zeige CRY2 ELISA Kits) domain of TIFA (zeige IL22 ELISA Kits), leading to TIFA (zeige IL22 ELISA Kits) oligomerization and TIFA (zeige IL22 ELISA Kits)-mediated NF-kappaB (zeige NFKB1 ELISA Kits) activation

  5. TIFA (zeige IL22 ELISA Kits) induces the oligomerization and polyubiquitination of TRAF6 (zeige TRAF6 ELISA Kits), which leads to the activation of TAK1 (zeige MAP3K7 ELISA Kits) and IKK (zeige CHUK ELISA Kits) through a proteasome-independent mechanism

Mouse (Murine) TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) Interaktionspartner

  1. The increase in TIFA level appears to be a feed-forward mechanism involved in TLR4 (zeige TLR4 ELISA Kits)/MyD88 (zeige MYD88 ELISA Kits)-dependent signaling, leading to NF-kappaB (zeige NFKB1 ELISA Kits) activation and HMGB1 (zeige HMGB1 ELISA Kits) release

  2. TIFA is likely to mediate IRAK-1 (zeige IRAK1 ELISA Kits)/TRAF6 (zeige TRAF6 ELISA Kits) interaction upon IL-1 (zeige IL1A ELISA Kits) stimulation

  3. We propose that ZCCHC11 (zeige ZCCHC11 ELISA Kits) is a unique TLR signal regulator, which interacts with TIFA after LPS (zeige TLR4 ELISA Kits) treatment and suppresses the TRAF6 (zeige TRAF6 ELISA Kits)-dependent activation of NF-kappaB (zeige NFKB1 ELISA Kits).

TIFA Antigen-Profil

Beschreibung des Gens

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Genbezeichner und Symbole assoziert mit TIFA

  • TRAF interacting protein with forkhead associated domain (TIFA) Antikörper
  • TRAF-interacting protein with forkhead-associated domain (tifa) Antikörper
  • TRAF-interacting protein with forkhead-associated domain (Tifa) Antikörper
  • TRAF-interacting protein with forkhead-associated domain S homeolog (tifa.S) Antikörper
  • Ab2-389 Antikörper
  • T2bp Antikörper
  • T6BP Antikörper
  • TIFA Antikörper
  • TIFAA Antikörper
  • xtifa Antikörper

Bezeichner auf Proteinebene für TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPEZIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
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