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The protein encoded by TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. Zusätzlich bieten wir Ihnen TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 Antikörper (28) und viele weitere Produktgruppen zu diesem Protein an.
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Data indicate that both ELAVL1 and TIAR positively regulate endogenous SNCA in vivo.
we identified MT1JP as a critical factor in restraining cell transformation by modulating p53 (zeige TP53 Proteine) translation through interactions with TIAR
Data suggest that TPD52 (tumor protein D52) and a TPD52 fragment (residues 78-280) along with TIA-1 (zeige TIA1 Proteine) (T-cell intracellular antigen-1) and TIAR (TIA-1-related protein) contribute to mRNA stability as cis (zeige CISH Proteine)-acting and trans-acting factors; 3prime-untranslated regions of TPD52, TPD53, and TPD54 regulate expression of their respective genes in a post-transcriptional manner by altering mRNA stability.
results suggest that TIA-1 and TIAR are two new host factors that interact with 5-UTR of EV71 genome and positively regulate viral replication
TIAL1 inhibition of the exon 8 exclusion led to a decrease in SIRT1 (zeige SIRT1 Proteine)-Exon8 mRNA levels.
TIA proteins can function as long-term regulators of the ACTB (zeige ACTB Proteine) mRNA metabolism in mouse and human cells.
A role for TIAR is identified in T-cells for control of translational specificity.
findings demonstrate that TIAR recognition motif 2 (RRM2 (zeige RRM2 Proteine)), together with its C-terminal extension, is the major contributor for the high-affinity (nM) interactions of TIAR with target RNA sequences
TIA1 (zeige TIA1 Proteine) and TIAR proteins are intron-associated positive regulators of SMN2 (zeige SMN1 Proteine) exon 7 splicing.
Severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1alpha (zeige HIF1A Proteine) expression.
Silencing of TIAR in chronic myeloid leukemia cells strongly elevated BRCA1.
Either TIA1 (zeige TIA1 Proteine) or TIAR inactivation broadly alter normal development-associated signalling pathways in murine embryonic fibroblasts.
study reports the importance of the tightly balanced expression of the RNA-binding protein TIAR for normal embryonic development, thereby emphasizing the role of post-transcriptional regulations in early embryonic programming
prion (zeige PRNP Proteine)-like aggregation of TIA-1 (zeige TIA1 Proteine) regulates stress granules formation downstream of eIF2alpha (zeige EIF2A Proteine) phosphorylation in response to stress
in addition to transcriptional regulation, another mechanism by which apigenin prevents COX-2 expression is through mediating TIAR suppression of translatino
TIAR regulates the relative expression of TIA-1 (zeige TIA1 Proteine) isoforms.
TIA1 (zeige TIA1 Proteine) and TIAL1 regulate the alternate splicing of lysyl hydroxylase 2 (zeige PLOD2 Proteine)
The intronic splicing enhancer of minute virus of mice binds the cellular RNA-processing proteins TIA-1 (zeige TIA1 Proteine) and TIAR, which enhance usage of the nonconsensus donor.
SOD1 (zeige SOD1 Proteine) sequesters Hu antigen R (HuR (zeige ELAVL1 Proteine)) and TIA-1-related protein (TIAR) and has a role in impaired post-transcriptional regulation of vascular endothelial growth factor (zeige VEGF Proteine)
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
TIA1 cytotoxic granule-associated RNA binding protein-like 1
, nucleolysin TIAR
, T-cluster binding protein
, TIA-1-related nucleolysin
, aging-associated gene 7 protein
, TIA-1-related protein
, Tial1 cytotoxic granule-associated RNA binding protein-like 1
, Tial1 cytotoxic granule-associated RNA-binding protein-like 1
, RNA binding protein TIAR (TIA-1 related)
, Tial 1 cytotoxic granule-associated RNA- binding protein-like 1