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The protein encoded by THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. Zusätzlich bieten wir Ihnen THO Complex 4 Antikörper (56) und THO Complex 4 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
ALYREF mainly binds to the 5' and the 3' regions of the mRNA. ALYREF is likely recruited to mRNAs by PABPN1 (zeige PABPN1 ELISA Kits) and the 3' processing machinery.
The competition between hMTR4 and ALYREF determines exosome recruitment and functions in creating balanced nuclear RNA pools for degradation and export.
small hairpin RNA-mediated down-regulation of TAP or Aly reduced nuclear export of HDAg-L and assembly of HDV virions. Furthermore, a peptide, TAT (zeige TAT ELISA Kits)-HDAg-L(198-210), containing the 10-amino acid TAT (zeige TAT ELISA Kits) peptide and HDAg-L(198-210), inhibited the interaction between HDAg-L and TAP and blocked HDV virion assembly and secretion.
A short conserved motif in ALYREF directs cap- and exon junction complex-dependent assembly of export complexes on spliced mRNAs.
the data provides the first site-specific description of how viral mRNA is locked by a herpes viral adaptor protein in complex with cellular ALYREF, giving herpesvirus access to the cellular mRNA export machinery
a spatial map is produced in living cells of the sites for the interaction of two TREX subunits, Alyref and Chtop (zeige CHTOP ELISA Kits), with Nxf1 (zeige NXF1 ELISA Kits).
ALY is a novel E2F2 (zeige E2F2 ELISA Kits)-interacting protein and a relevant modulator of E2F (zeige E2F1 ELISA Kits)-responsive gene expression.
The interaction of the cellular export adaptor protein Aly/REF with ICP27 contributes to the efficiency of herpes simplex virus 1 mRNA export.
High ALY expression is associated with lymph node metastasis in oral squamous cell carcinoma.
Authors propose that Aly, THO (zeige THOC2 ELISA Kits) and UAP56 (zeige DDX39B ELISA Kits) form a highly integrated unit to associate with the spliced mRNA and function in mRNA export.
Structure of the nuclear factor ALY provides insights into post-transcriptional regulatory and mRNA nuclear export processes.
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
THO complex 4
, THO complex subunit 4
, ally of AML-1 and LEF-1
, bZIP enhancing factor
, bZIP-enhancing factor BEF
, transcriptional coactivator Aly/REF
, THO complex subunit 4-A
, aly/REF export factor-A
, RNA and export factor binding protein 1
, RNA and export factor-binding protein 1
, Tcra enhancer-binding factor interacting protein 1
, aly/REF export factor
, putative disulfide-isomerase