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TBPL1 encodes a member of the TATA box-binding protein family. Zusätzlich bieten wir Ihnen TBPL1 Proteine (15) und TBPL1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 128 products:
Human Monoclonal TBPL1 Primary Antibody für ChIP, CyTOF - ABIN252470
Stavropoulos, Bradshaw, Li, Pasic, Truong, Ikura, Ungrin, Meyn: The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis. in Human molecular genetics 2002
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Chinese Hamster Polyclonal TBPL1 Primary Antibody für ChIP, ICC - ABIN189464
Smith, de Lange: Tankyrase promotes telomere elongation in human cells. in Current biology : CB 2001
Show all 47 Pubmed References
Human Polyclonal TBPL1 Primary Antibody für ChIP, ICC - ABIN252639
Mearini, Chichiarelli, Zampieri, Masciarelli, DErme, Ferraro, Mattia: Interaction of EBV latent origin of replication with the nuclear matrix: identification of S/MAR sequences and protein components. in FEBS letters 2003
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Dog (Canine) Monoclonal TBPL1 Primary Antibody für WB - ABIN968416
Broccoli, Smogorzewska, Chong, de Lange: Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. in Nature genetics 1997
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Human Monoclonal TBPL1 Primary Antibody für IHC, WB - ABIN2668524
Martianov, Fimia, Dierich, Parvinen, Sassone-Corsi, Davidson: Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene. in Molecular cell 2001
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Human Polyclonal TBPL1 Primary Antibody für ELISA, WB - ABIN249650
Ohbayashi, Kishimoto, Makino, Shimada, Nakadai, Aoki, Kawata, Niwa, Tamura: Isolation of cDNA, chromosome mapping, and expression of the human TBP-like protein. in Biochemical and biophysical research communications 1999
Human Polyclonal TBPL1 Primary Antibody für WB - ABIN1875056
Liu, Liu, Yang, Wang, Li, Zhang: Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells. in Molecular medicine reports 2015
TLP Prevents p53 (zeige TP53 Antikörper) Degradation through Disrupting the p53 (zeige TP53 Antikörper)-MDM2 (zeige MDM2 Antikörper) Interaction.
The interaction of TBP (zeige TBP Antikörper)-like protein with TFIIA (zeige GTF2A1 Antikörper) is essential to suppress proteasome-dependent turnover of TBP (zeige TBP Antikörper)-like protein
miR18a exhibits a protective role in colorectal cancer (CRC (zeige CALR Antikörper)) via inhibiting proliferation, invasion and migration of CRC (zeige CALR Antikörper) cells by directly targeting the TBPL1 gene.
results suggest that activation of the p21 (zeige CDKN1A Antikörper) upstream promoter is mediated by interaction between specific regions of TLP and p53 (zeige TP53 Antikörper)
Western blotting and immunohistochemistry both indicated a higher TBPL1 protein expression level in colorectal cancer tissue. siRNA for TBPL1 transfection obviously slowed down the cell proliferation in both SW-620 and HT-29 cells.
TLP mediates p53 (zeige TP53 Antikörper)-governed transcriptional activation of the p21 (zeige CDKN1A Antikörper) upstream promoter.
Data show that during interphase, endogenous or exogenously expressed TRF2 (zeige TERF2 Antikörper) is located almost exclusively in the nucleolus
TLF is a functional regulator of transcription with targets distinct from those of TBP (zeige TBP Antikörper).
the knockdown of the endogenous TLP reduced etoposide-induced apoptosis through repression of TAp63 expression. Taken together, our present study identifies a TLP-TAp63 pathway that is further implicated in stress-induced apoptosis.
Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.
Transplantation of TRF2 (zeige TERF2 Antikörper) overexpressing bone marrow cells into the hematopoietic system of mice resulted in the the development of T-cell lymphomas, but overexpression of the TRF2 (zeige TERF2 Antikörper) transgene was not detectable anymore in the tumors.
transcription factor IIA may regulate the intracellular molecular state and the function of TATA-binding protein-like protein (TLP) through its property of binding to TLP
TBP-related factor 2 (TRF2) has a role in mouse spermatogenesis
reconfirmed cytoplasmic localization of TRF2 (zeige TERF2 Antikörper); genotoxins caused it to migrate to the nucleus; TRF2 (zeige TERF2 Antikörper) may be involved in genotoxin-induced transcriptional regulation
these results demonstrate that TRF2 (zeige TERF2 Antikörper) increased expression is a potent oncogenic event that along with telomerase deficiency accelerates carcinogenesis, coincidental with a derepression of telomere recombination
Data report on the nucleosomal organization of telomeres that have become deprotected through the deletion of the shelterin components TRF2 (zeige TERF2 Antikörper) or POT1a (zeige POT1 Antikörper)/b, and show no evidence of changes or nucleosome eviction near the telomere terminus.
Role of TRF2 (zeige TERF2 Antikörper) mRNA in male germ cells: In transgenic animals deficient in TRF2 (zeige TERF2 Antikörper), spermatid development fails during early spermiogenesis with increased apoptosis and failure to develop testicular spermatozoa. Infertility phenotype in homozygote males.
Mice lacking the TBP-related factor 2 (TRF2) gene, which is highly expressed in the testis, have a severe defect in spermiogenesis. TRF2 (zeige TERF2 Antikörper) expression is shown to be cell type- and stage-specific and play an essential regulatory role in development.
Arabidopsis Pol II (zeige 0 Antikörper) is indispensable for endogenous siRNA-mediated transcriptional gene silencing (TGS (zeige LIN9 Antikörper)) at intergenic low-copy-number loci, despite the presence of two other polymerases-Pol IV and Pol V-that specialize in TGS (zeige LIN9 Antikörper) through siRNAs
This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
21-kDA TBP-like protein
, TATA box-binding protein-like protein 1
, TATA box-binding protein-related factor 2
, TBP-related factor 2
, TBP-related protein
, second TBP of unique DNA protein
, MIID(1)-5.1 (Probe)
, TATA sequence-binding protein 1
, TATA-binding factor 1
, TATA-binding protein
, TATA-box binding protein
, TATA-box factor 1
, TATA-box-binding protein 1
, TATA-box-binding protein 1(TATA-binding factor 1)(TATA sequence-binding protein 1)
, hypothetical protein
, transcription initiation factor TFIID TBP-1 subunit
, TBP-like factor
, TBP-like protein 1
, TATA box binding protein-like 1
, TATA box-binding protein related factor 2
, TBP-like 1
, tata box-binding protein-like protein 1
, 21 kDa TBP-like protein
, TATA box binding protein-like protein