T-Box 4 (TBX4) ELISA Kits

TBX4 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. Zusätzlich bieten wir Ihnen TBX4 Antikörper (35) und TBX4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TBX4 9496 P57082
Anti-Maus TBX4 TBX4 21387 P70325
Anti-Ratte TBX4 TBX4 303399  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für TBX4 Interaktionspartner

Human T-Box 4 (TBX4) Interaktionspartner

  1. We propose phenotypic expansion of the TBX4-related clinical disease spectrum to include acinar dysplasia of the lungs. The reported mutation is the first identified genetic variant causative for acinar dysplasia.

  2. TBX4 is a mesenchymal transcription factor that drives accumulation of myofibroblasts and the development of lung fibrosis

  3. In a cohort with idiopathic or hereditary pulmonary arterial hypertension, a possibly associated mutation was found in 11.10% of the idiopathic cases (n = 16) and in 68.18% of the hereditary cases. There were 4 mutations found in TBX4.

  4. a low level of TBX4 expression suggests a worse prognosis for patients with stage II PDAC. Down-regulation of the TBX4 gene in pancreas is less likely to be regulated by DNA methylation.

  5. Although TBX4 remains the candidate gene for congenital clubfoot involving 17q23.1-q23.2 duplications, the explanation for variable expressivity and penetrance remains unknown.

  6. data indicate that TBX4 mutations are associated with childhood-onset pulmonary arterial hypertension (PAH), but the prevalence of PAH in adult TBX4 mutation carriers is low

  7. Minimal evidence was found for an association between TBX4 and clubfoot and no pathogenic sequence variants were identified in the two known TBX4 hindlimb enhancer elements.

  8. Microdeletion of 17q22q23.2 encompassing TBX2 (zeige TBX2 ELISA Kits) and TBX4 in a patient with congenital microcephaly, thyroid duct cyst, sensorineural hearing loss, and pulmonary hypertension.

  9. Mutations in the human TBX4 gene cause small patella syndrome

Mouse (Murine) T-Box 4 (TBX4) Interaktionspartner

  1. TBX4 is a mesenchymal transcription factor that drives accumulation of myofibroblasts and the development of lung fibrosis

  2. These data extend our understanding of the role and regulation of Tbx4 and Shox2 in limb development and limb associated diseases.

  3. Although postnatal deletion of Tbx4 in oocytes does not obviously impair fertility, it is possible that the reduction in primordial germ cells observed in Tbx4 homozygous null mutant embryos could affect long-term fertility in adults.

  4. Candidate gene approach identifies multiple genes and signaling pathways downstream of Tbx4 in the developing allantois

  5. Mice deficient in Tbx4 and Tbx5 show severely reduced lung branching at mid-gestation.

  6. Tbx4 expression and lineage reveal that various distinct appendages, such as the allantois, hindlimb, and external genitalia, all arise from a single mesenchymal expression domain.

  7. It was shown that, firstly, Pitx1 (zeige PITX1 ELISA Kits) influences hindlimb outgrowth by regulating Tbx4 expression levels and that, subsequently,Pitx1 (zeige PITX1 ELISA Kits) shapes hindlimb bone and soft tissue morphology independently of Tbx4.

  8. Study find that Tbx4 is the primary effector of HL identity for both skeletal and muscle development.

  9. Tbx4 is reported to play a key role in separation of the respiratory tract and the esophagus.

  10. Deletion of Tbx4 in hindlimbs specifically affects muscle and tendon patterning without disrupting skeletal development, thus suggesting that distinct cues regulate these processes.

TBX4 Antigen-Profil

Beschreibung des Gens

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

Genbezeichner und Symbole assoziert mit T-Box 4 (TBX4) ELISA Kits

  • T-box 4 (tbx4) Antikörper
  • T-box 4 (TBX4) Antikörper
  • T-box 4 (Tbx4) Antikörper
  • 3930401C23 Antikörper
  • SPS Antikörper
  • TBX4 Antikörper
  • zf-tbx4 Antikörper
  • zTbx4 Antikörper

Bezeichner auf Proteinebene für T-Box 4 (TBX4) ELISA Kits

T-box gene 4 , T-box transcription factor TBX4 , T-Box protein 4 , T-box 4 , T-box transcription factor TBX4-like , t-box transcription factor TBX4-like , T-box 4 protein , T-box protein 4 , transcription factor Tbx4

30070 Danio rerio
373989 Gallus gallus
508750 Bos taurus
737130 Pan troglodytes
100010048 Monodelphis domestica
100350522 Oryctolagus cuniculus
100411523 Callithrix jacchus
100459174 Pongo abelii
100591386 Nomascus leucogenys
100620126 Sus scrofa
9496 Homo sapiens
403514 Canis lupus familiaris
21387 Mus musculus
303399 Rattus norvegicus
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