Surfactant Protein A1 Proteine (SFTPA1)

SFTPA1 encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. Zusätzlich bieten wir Ihnen Surfactant Protein A1 Antikörper (127) und Surfactant Protein A1 Kits (82) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SFTPA1 653509 Q8IWL2
SFTPA1 24773 P08427
SFTPA1 20387  
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Top Surfactant Protein A1 Proteine auf antikoerper-online.de

Showing 10 out of 21 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
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Escherichia coli (E. coli) Human His tag,S tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$729.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,572.17
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Hefe Pferd His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,572.17
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Hefe Rhesusaffen His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,572.17
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Hefe Meerschweinchen His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,572.17
Details

SFTPA1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , , ,
Rat (Rattus) ,
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Mouse (Murine) ,
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Am meisten referenzierte Surfactant Protein A1 Proteine

  1. Mouse (Murine) Surfactant Protein A1 Protein expressed in Escherichia coli (E. coli) - ABIN2126881 : Su, Shi, Liu, Huang, Huang, Nie: Metabolic profiling of asthma in mice and the interventional effects of SPA using liquid chromatography and Q-TOF mass spectrometry. in Molecular bioSystems 2017 (PubMed)

Weitere Proteine zu Surfactant Protein A1 (SFTPA1) Interaktionspartnern

Human Surfactant Protein A1 (SFTPA1) Interaktionspartner

  1. this study shows that concentrations of SP-A are associated with polarization of macrophages in pleural effusions of non-small cell lung cancer

  2. the SPA (zeige FASL Proteine) and SPD (zeige HOXD13 Proteine) levels in EBC were correlated with lung function, which contributed to COPD (zeige ARCN1 Proteine) diagnosis.

  3. Data (including data from studies using transgenic/knockout mice) suggest that surfactant protein A1 (SPA1) interferes with EGF (zeige EGF Proteine) binding to EGFR (zeige EGFR Proteine) in pulmonary alveoli cell lines; SPA1 (zeige SIPA1 Proteine) directly binds extracellular domain of EGFR (zeige EGFR Proteine); binding of SPA1 (zeige SIPA1 Proteine) to EGFR (zeige EGFR Proteine) appears to be different from binding of SPD (zeige HOXD13 Proteine) to EGFR (zeige EGFR Proteine); binding of SPA1 (zeige SIPA1 Proteine) to EGFR (zeige EGFR Proteine) does not suppress EGF (zeige EGF Proteine)-induced phosphorylation of EGFR (zeige EGFR Proteine) or cell proliferation.

  4. This review intends to provide a current overview of the genetics, structure and extra-pulmonary functions of the surfactant collectin (zeige MBL2 Proteine) proteins.

  5. The SFTPA1 haplotype comprising rs17881720-A and rs17879335-G was a resistance factor while the haplotype comprising rs1914663-T and rs1059225-G was found to be a susceptibility factor to tuberculosis in Han Chinese population.

  6. SP-A transiently enhances the basal protein expression of CHC and alpha-adaptin.

  7. SP-A1 6A4 and SP-A2 1A5 genetic variants may influence the susceptibility to respiratory distress syndrome in late-preterm infants, independently of the effect of other perinatal factors.

  8. Direct interaction between SP-A or SAP01 and human BD-3 (zeige DEFB103A Proteine) seemed to be responsible for the inhibitory effects on chemotaxis of mast cells.

  9. SP-A (+186A/G) and SP-B (1580C/T) polymorphisms are strongly associated with the risk of respiratory distress syndrome (RDS (zeige PRPH2 Proteine)) in preterm infants. Notably, reduced serum SP-A levels were correlated with a high risk of RDS (zeige PRPH2 Proteine) and may serve as novel biomarkers for RDS (zeige PRPH2 Proteine) detection and monitoring.

  10. Surfactant protein A (zeige GPR153 Proteine) levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.

Pig (Porcine) Surfactant Protein A1 (SFTPA1) Interaktionspartner

  1. SP-A inhibited the infectivity of porcine reproductive and respiratory syndrome virus in Marc (zeige CCL7 Proteine) 145 cells and could reduce the total RNA and protein level.

  2. identification of a polymorphism of the porcine SFTPA1 gene coding region that is associated with acute lung injury

  3. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A, SP-B and SP-C (zeige SFTPC Proteine) preparations.

  4. PSP-A plays a significant physiological role as an antioxidant protecting the lung during the oxidative stress.

  5. Pulmonary surfactant-associated protein A (SP-A) is detected in thymus, trachea, lung, jejunum, and duodenum.

Cow (Bovine) Surfactant Protein A1 (SFTPA1) Interaktionspartner

  1. gene encoding bovine surfactant protein A (zeige GPR153 Proteine) maps to the same locus on chromosome 28 as other collectins

Mouse (Murine) Surfactant Protein A1 (SFTPA1) Interaktionspartner

  1. The data provide evidence SP-A and SP-D (zeige SFTPD Proteine) attenuate S. aureus pneumonia severity resulting in decreased intestinal mucosal injury, apoptosis, and inflammation.

  2. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A and SPC (zeige SFTPC Proteine) but not SPB and SPD (zeige SFTPD Proteine) expression.

  3. Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A, SP-D (zeige SFTPD Proteine) and MBL-A) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS (zeige TLR4 Proteine) challenge are clues relevant to suggest their involvement in testicular immune privilege.

  4. SP-A/D double knock-out mice showed increased susceptibility to urinary tract infection

  5. Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.

  6. The presence of SP-A and SP-D (zeige SFTPD Proteine) in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.

  7. Data show that the type IV pilus (Tfp (zeige TRIM39 Proteine))-deficient mutant DeltapilA is severely attenuated in an acute pneumonia model of infection in the lungs of wild-type mice, but is virulent in the lungs of surfactant protein-A (zeige GPR153 Proteine) SP-A(-/-) mice.

  8. SP-A and SP-D (zeige SFTPD Proteine) attenuate kidney injury by modulating inflammation and apoptosis in sepsis-induced AKI.

  9. Maternal SP-A impacts milk sIgA and cytokine content, and is associated with improved newborn health.

  10. peptide from the interface with TLR4 (zeige TLR4 Proteine) inhibits endotoxic shock-like symptoms in a mouse model

Surfactant Protein A1 (SFTPA1) Protein Überblick

Protein Überblick

This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit Surfactant Protein A1 Proteine (SFTPA1)

  • surfactant protein A1 (SFTPA1)
  • surfactant protein A1 (Sftpa1)
  • pulmonary surfactant-associated protein A-like (LOC610540)
  • surfactant associated protein A1 (Sftpa1)
  • pulmonary surfactant-associated protein A (LOC102175746)
  • COLEC4 Protein
  • LL Protein
  • PSAP Protein
  • PSP-A Protein
  • PSPA Protein
  • Sftp-1 Protein
  • Sftp1 Protein
  • SFTPA Protein
  • SFTPA1B Protein
  • SFTPA2 Protein
  • SFTPA2B Protein
  • Sftpl Protein
  • SP-a Protein
  • SP-A1 Protein
  • SPA Protein
  • SPA1 Protein

Bezeichner auf Proteinebene für Surfactant Protein A1 Proteine (SFTPA1)

35 kDa pulmonary surfactant-associated protein , alveolar proteinosis protein , collectin-4 , pulmonary surfactant-associated protein A1 , surfactant protein A1 variant AB'D' 6A , surfactant protein A1 variant AB'D' 6A2 , surfactant protein A1 variant AB'D' 6A3 , surfactant protein A1 variant AB'D' 6A4 , surfactant protein A1 variant ACD' 6A , surfactant protein A1 variant ACD' 6A2 , surfactant protein A1 variant ACD' 6A3 , surfactant protein A1 variant ACD' 6A4 , surfactant protein A1 variant AD' 6A , surfactant protein A1 variant AD' 6A2 , surfactant protein A1 variant AD' 6A3 , surfactant protein A1 variant AD' 6A4 , surfactant protein A1B , surfactant, pulmonary-associated protein A1A , surfactant, pulmonary-associated protein A1B , PSAP , PSP-A , Surfactant-associated protein 1 (pulmonary surfactant protein SP-A) , Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A) , pulmonary surfactant-associated protein A , surfactant associated protein A , surfactant, pulmonary-associated protein A1 , SP-A , surfactant protein A , surfactant protein A2B , surfactant, pulmonary-associated protein A2 , surfactant, pulmonary-associated protein A2B , surfactant pulmonary associated protein A1 , pulmonary surfactant protein A , surfactant, pulmonary-associated protein A , lung lectin , surfactant protein A1

GENE ID SPEZIES
653509 Homo sapiens
24773 Rattus norvegicus
397503 Sus scrofa
443033 Ovis aries
574108 Macaca mulatta
610540 Canis lupus familiaris
100009044 Oryctolagus cuniculus
407213 Bos taurus
20387 Mus musculus
100135615 Cavia porcellus
100033826 Equus caballus
102175746 Capra hircus
423630 Gallus gallus
Ausgewählte Anbieter für Surfactant Protein A1 Proteine (SFTPA1)
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