Spindle and Kinetochore Associated Complex Subunit 3 Proteine (SKA3)

SKA3 encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. Zusätzlich bieten wir Ihnen SKA3 Antikörper (57) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SKA3 221150 Q8IX90
SKA3 361047  
SKA3 219114 Q8C263
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Top SKA3 Proteine auf antikoerper-online.de

Showing 6 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,116.67
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Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,402.67
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,166.17
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SKA3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Interaktionspartnern

Human Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Interaktionspartner

  1. decreased neuronal cell SKA complex genes' expression levels affect neuronal cell viability and neurite development

  2. Study shows that Cdk1 phosphorylates Ska3 to promote its direct binding to the Ndc80 complex (Ndc80C), a core outer kinetochore component, also show that this phosphorylation occurs specifically during mitosis and is required for the kinetochore localization of the Ska complex.

  3. this report provides clear evidence that overexpression of the AURKA (zeige AURKA Proteine), SKA3, and DSN1 (zeige DSN1 Proteine) genes strongly correlates with the progression of colorectal adenomas to colorectal cancer

  4. Kinetochores mature through Ska1 (zeige SKA1 Proteine)/ska2 (zeige FAM33A Proteine)/Ska3 complex recruitment and this is required for improved load-bearing capacity and silencing of the spindle assembly checkpoint.

  5. over-expression of GNL3 (zeige E2IG3 Proteine) and SKA3 in the PC-3 (zeige PCSK1 Proteine) human prostate cancer cell line decreased in vitro cell migration and invasion

  6. The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1 (zeige SKA1 Proteine), Ska2 (zeige FAM33A Proteine), and Ska3.

  7. Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.

  8. Ska3 functions to coordinate checkpoint signaling from the microtubule binding sites within a kinetochore by laterally linking the individual binding sites.

  9. C13Orf3 (now termed Ska3) localizes to the spindle and kinetochore throughout mitosis and its depletion markedly delays anaphase transition.

  10. These data identify C13orf3 (Ska3) as an important factor for metaphase to anaphase progression and highlight the potential of combined RNAi screening and protein localisation analyses.

Mouse (Murine) Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Interaktionspartner

  1. The Ska3 subunit was only localized on spindle microtubules from the Pro-MI to MII stages in mouse oocyte meiosis and knockdown by Morpholino injection into mouse oocytes resulted in spindle movement defects and enlarged polar bodies.

SKA3 Protein Überblick

Protein Überblick

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit SKA3

  • spindle and kinetochore associated complex subunit 3 (SKA3)
  • spindle and kinetochore associated complex subunit 3 (Ska3)
  • spindle and kinetochore associated complex subunit 3 (ska3)
  • spindle and kinetochore associated complex subunit 3 L homeolog (ska3.L)
  • C12H13ORF3 Protein
  • C13orf3 Protein
  • F630043A04Rik Protein
  • fc23d11 Protein
  • rama1 Protein
  • RGD1307201 Protein
  • si:rp71-68n21.13 Protein
  • wu:fc23d11 Protein

Bezeichner auf Proteinebene für SKA3

spindle and kinetochore-associated protein 3 , spindle and kinetochore associated complex subunit 3 , Spindle and kinetochore-associated protein RAMA1

GENE ID SPEZIES
221150 Homo sapiens
361047 Rattus norvegicus
452468 Pan troglodytes
509921 Bos taurus
570479 Danio rerio
609400 Canis lupus familiaris
702839 Macaca mulatta
100055242 Equus caballus
100144945 Xenopus (Silurana) tropicalis
100158292 Xenopus laevis
100344062 Oryctolagus cuniculus
100450023 Pongo abelii
100595589 Nomascus leucogenys
219114 Mus musculus
418948 Gallus gallus
100726229 Cavia porcellus
Ausgewählte Anbieter für SKA3 Proteine (SKA3)
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