Spi-C Transcription Factor (Spi-1/PU.1 Related) Proteine (SPIC)

Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis.

alle Proteine anzeigen Gen GeneID UniProt
Human SPIC SPIC 121599 Q8N5J4
Maus SPIC SPIC 20728 Q6P3D7
Ratte SPIC SPIC 314711  
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Top Spi-C Transcription Factor (Spi-1/PU.1 Related) Proteine auf antikoerper-online.de

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
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Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen Verfügbar
$284.90
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,634.50
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Escherichia coli (E. coli) Toxoplasma gondii Unkonjugiert   500 μg Anmelden zum Anzeigen 2 bis 3 Tage
$437.86
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Weitere Proteine zu Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Interaktionspartnern

Human Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Interaktionspartner

  1. A protein interaction between SPI-C and STAT6 (zeige STAT6 Proteine) is the basis for a novel mechanism for regulation of IL4 (zeige IL4 Proteine) induced gene expression.

Mouse (Murine) Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Interaktionspartner

  1. These results indicate a novel role for Spi-C as a negative regulator of B cell development and function.

  2. Study reports that Spic regulated the development of F4/80(+)VCAM1 (zeige VCAM1 Proteine)(+) bone marrow macrophages (BMM) and that Spic expression in BMM and red pulp macrophages development was induced by heme, a metabolite of erythrocyte degradation.

  3. Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B (zeige SPIB Proteine), and Spi-C.

  4. The Kit-activating mutations cooperate with Spi-1 (zeige SPI1 Proteine)/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.

  5. Spi-C has the potential to modulate PU.1 activity to promote B cell differentiation.

  6. data indicate that ectopic expression of Spi-C can impair B-cell development and function by affecting genes associated with BCR (zeige BCR Proteine) signaling

  7. Spi-C controls development of red pulp macrophages required for red blood cell recycling and iron homeostasis

Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Protein Überblick

Protein Überblick

Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).

Genbezeichner und Symbole assoziert mit SPIC

  • Spi-C transcription factor (SPIC)
  • transcription factor Spi-C-like (LOC100349167)
  • Spi-C transcription factor (Spi-1/PU.1 related) (Spic)
  • Spi-C transcription factor (Spic)
  • Spi-C transcription factor (Spi-1/PU.1 related) (spic)
  • Spi-C transcription factor (Spi-1/PU.1 related) S homeolog (spic.S)
  • AU019198 Protein
  • C76795 Protein
  • Prf Protein
  • spi-c Protein
  • spic Protein
  • zgc:101790 Protein

Bezeichner auf Proteinebene für SPIC

transcription factor Spi-C , Spi-C transcription factor (Spi-1/PU.1 related) , pu.1-related factor , Spi-C transcription factor (Spi-1/PU.1 related) S homeolog

GENE ID SPEZIES
121599 Homo sapiens
100349167 Oryctolagus cuniculus
612169 Canis lupus familiaris
616438 Bos taurus
20728 Mus musculus
314711 Rattus norvegicus
100719534 Cavia porcellus
447882 Danio rerio
446812 Xenopus laevis
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