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The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Zusätzlich bieten wir Ihnen S1PR5 Antikörper (136) und S1PR5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Reduced DNA methylation may underlie the increased expression of the S1PR5 gene in alveolar macrophages and associated defective efferocytosis in COPD (zeige ARCN1 ELISA Kits).
Data indicate that the mitotic kinase Polo-like kinase 1 (PLK1 (zeige PLK1 ELISA Kits)) was an important effector of S1P-S1P5 signaling, and a new function of the SphK1 (zeige SPHK1 ELISA Kits)-S1P pathway specifically in the control of mitosis in HeLa cells.
TGF-beta2 (zeige TGFB2 ELISA Kits) dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF (zeige CTGF ELISA Kits) by TGF-beta (zeige TGFB1 ELISA Kits) in mesangial cells.
This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss.
Data show that sphingosine kinase SphK1 (zeige SPHK1 ELISA Kits) and sphingosine-1-phosphate (S1P) receptors S1P1 (zeige S1PR1 ELISA Kits), S1P2 (zeige S1PR2 ELISA Kits), S1P3 (zeige S1PR3 ELISA Kits), and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (zeige SPHK2 ELISA Kits) levels were highest in primary tumors.
Edg-5 (zeige S1PR2 ELISA Kits) receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium.
The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation.
The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.
FTY720 induces time-dependent modulation of S1P receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process.
The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis.
Coordinated changes in CXCR4 (zeige CXCR4 ELISA Kits) and S1P5 responsiveness govern NK-cell trafficking.
Fndings suggest that S1P (zeige S1PR1 ELISA Kits)(5) may mediate the effects of S1P (zeige S1PR1 ELISA Kits) in terms of regulating ERK-1 (zeige MAPK3 ELISA Kits)/2 signaling in ES cells.
Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell.
Sphingosine 1-phosphate receptors regulate chemokine (zeige CCL1 ELISA Kits)-driven transendothelial migration of lymph node but not splenic T cells.
KLF2 (zeige KLF2 ELISA Kits) regulates T cell homeostasis at least partly by controlling CD62L (zeige SELL ELISA Kits) and S1P1 (zeige S1PR1 ELISA Kits) expression, and therefore T cell egress from the thymus and circulation in the periphery.
These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow.
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\; MIM 601974) are S1P receptors\; others (e.g., EDG2\; MIM 602282) are LPA receptors.
S1P receptor 5
, S1P receptor Edg-8
, endothelial differentiation G-protein-coupled receptor 8
, endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
, sphingosine 1-phosphate receptor 5
, sphingosine 1-phosphate receptor EDG8
, sphingosine 1-phosphate receptor Edg-8
, Sphingosine 1-phosphate receptor Edg-8
, endothelial differentiation, sphingolipid G-protein-coupled receptor 8
, lysophospholipid receptor B4
, sphingosine-1-phosphate receptor LPB4
, nerve growth factor-regulated G-protein-coupled receptor 1