Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Proteine (SLC8A3)

SLC8A3 encodes a member of the sodium/calcium exchanger integral membrane protein family. Zusätzlich bieten wir Ihnen Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Antikörper (56) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLC8A3 6547 P57103
Ratte SLC8A3 SLC8A3 140448 P70549
SLC8A3 110893  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Proteine auf antikoerper-online.de

Showing 3 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$7,639.51
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

SLC8A3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,

Weitere Proteine zu Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Interaktionspartnern

Human Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Interaktionspartner

  1. These results...suggest that cells can use a dynamic Ca(2 (zeige CA2 Proteine)+) signaling toolkit in which the NCX3 sub-cellular localization changes in synchrony with the cell cycle

  2. Structure-Dynamic Coupling Through Ca(2 (zeige CA2 Proteine)+)-Binding Regulatory Domains of Mammalian NCX (zeige TLX2 Proteine) Isoform/Splice Variants

  3. stimulation of NCX3 by PKA occurred through residue S524. This effect may well participate in the fight-or-flight response in skeletal muscle and the long-term potentiation in hippocampus.

  4. In the discovery phase, 60 loci not previously associated with rheumatoid arthritis risk showed evidence for association and were tested for replication in the validation cohort. A total of 12 loci were replicated at the nominal level. When combining the discovery and validation cohorts, an intronic SNP in SLC8A3 was found to be associated with ACPA (zeige PRTN3 Proteine)-positive rheumatoid arthritis at a genome-wide level of significance.

  5. Ayloid beta mediates calpain cleavage of NCX3 in Alzheimer's disease brain.

  6. NCX1 (zeige SLC8A1 Proteine) and NCX3 -represent two promising druggable targets for setting on new strategies in stroke therapy.

  7. NCX (zeige TLX2 Proteine) isoforms (NCX2, NCX3) contribute to mitochondrial Na(+)/Ca(2 (zeige CA2 Proteine)+) exchange in human DAergic neurons and may act downstream of PINK1 (zeige PINK1 Proteine) in the prevention of neurodegeneration by m[Ca(2 (zeige CA2 Proteine)+)] accumulation.

  8. the large cytosolic loop of NCX1 (zeige SLC8A1 Proteine), NCX2, and NCX3 is involved in acquisition of immunosuppressive drug specificity

  9. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte.

  10. human macrophages and monocytes express NCX1 (zeige SLC8A1 Proteine) and NCX3 that operate in a bidirectional manner to restore [Ca(2 (zeige CA2 Proteine)+)](i) to generate Ca(2 (zeige CA2 Proteine)+) signals and to induce TNF-alpha (zeige TNF Proteine) production.

Mouse (Murine) Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Interaktionspartner

  1. NCX2 and NCX3 protein and mRNA levels are relatively reduced in hippocampal CA1 of APP23 and APP-KI mice. Likewise, NCX2(+/-) or NCX3(+/-) mice exhibited impaired hippocampal LTP and memory-related behaviors. Moreover, relative to controls, calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation significantly decreased in NCX2(+/-) mouse hippocampus but increased in hippocampus of NCX3(+/-) mice.

  2. This study demonstrate that knocking-out NCX3 impairs oligodendrocyte response and worsens clinical symptoms in EAE without altering the immune T-cell population.

  3. Demonstrate that NCX3 genetic deletion protects against ziram-induced neurotoxicity and suggest NCX3 and its downstream molecular pathways as key factors involved in ziram toxicity.

  4. NCX3 regulates mitochondrial calcium handling from the outer mitochondrial membrane through an AKAP121 (zeige AKAP1 Proteine)-anchored signaling complex.

  5. Function and regulation of the Na+-Ca2+ exchanger (zeige SLC8A1 Proteine) NCX3 splice variants in brain and skeletal muscle.

  6. the use of genetic-modified mice for NCX1 (zeige SLC8A1 Proteine), NCX2, and NCX3 represents a fruitful strategy to characterize the physiological role exerted by NCX (zeige SLC8A1 Proteine) in CNS

  7. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte.

  8. the solution structure of NCX3 calcium binding domain 2B

  9. calcium signaling mediated by NCX3 has a crucial role in oligodendrocyte maturation and myelin formation.

  10. Results show that glucocorticoid treatment blunts LPS (zeige TLR4 Proteine)-induced increase in [Ca(2 (zeige CA2 Proteine)+)](i) in dendritic cells by increasing expression and activity of Na(+)/Ca(2 (zeige CA2 Proteine)+) exchanger NCX3.

Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Protein Überblick

Protein Überblick

This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

Genbezeichner und Symbole assoziert mit SLC8A3

  • solute carrier family 8 member A3 (SLC8A3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (SLC8A3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (slc8a3)
  • solute carrier family 8 member A3 (Slc8a3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (Slc8a3)
  • AW742262 Protein
  • Ncx3 Protein
  • SLC8A3 Protein

Bezeichner auf Proteinebene für SLC8A3

solute carrier family 8 (sodium-calcium exchanger), member 3 , solute carrier family 8 member 3 , solute carrier family 8 (sodium/calcium exchanger), member 3 , sodium/calcium exchanger 3-like , Na(+)/Ca(2+)-exchange protein 3 , Na+/Ca2+ exchanger 3 , sodium/calcium exchanger 3 , sodium/calcium exchanger SLC8A3 , sodium-calcium exchanger

GENE ID SPEZIES
467491 Pan troglodytes
490755 Canis lupus familiaris
100034161 Equus caballus
100152101 Sus scrofa
100339605 Oryctolagus cuniculus
100412630 Callithrix jacchus
100471755 Ailuropoda melanoleuca
100487508 Xenopus (Silurana) tropicalis
100541915 Meleagris gallopavo
100603298 Nomascus leucogenys
6547 Homo sapiens
140448 Rattus norvegicus
540307 Bos taurus
110893 Mus musculus
395759 Gallus gallus
Ausgewählte Anbieter für Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Proteine (SLC8A3)
Haben Sie etwas anderes gesucht?