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Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.. Zusätzlich bieten wir Ihnen SLC6A13 Antikörper (31) und viele weitere Produktgruppen zu diesem Protein an.
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Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents.
These findings demonstrate that GABA uptake and release via GAT-1, GAT-3, and VGAT are initially established in the inner retina during the first postnatal week and that these systems then mature in the outer retina during the second postnatal week.
Evidence for a Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters.
Neurotransmitter transporters including SLC6A6 and SLC6A13 mediate the uptake of 5-aminolevulinic acid (ALA) and can play roles in the enhancement of ALA-induced accumulation of protoporphyrin in cancerous cells.
Results suggest that gamma-aminobutyric acid transporter 2 GAT-2 is a high selectivity/low affinity transporter.
homology models of hGAT-2 and hGAT-3 were built and searched for (i) substrate conformation, (ii) prediction of substrate (inhibitor) interaction, and (iii) distinguishable allosteric Zn2+ inhibition by combining docking and MD calculations.
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
, gamma-aminobutyric acid (GABA-A) transporter 3
, sodium- and chloride-dependent GABA transporter 2
, sodium- and chloride-dependent GABA transporter 3
, solute carrier family 6 member 13
, Solute carrier family 6 member 13
, solute carrier family 6 (neurotransmitter transporter, GABA), member 13
, GABA transport protein
, GABA transporter 2