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Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
A low affinity type of SMCT2-like transporter is in operation with high capacity throughout the small intestine, playing the role as the major intestinal nicotinate uptake transporter.
SMCT2 was localized in the brush border of enterocytes in the intestinal villi, and SMCT2 was localized in the brush border of is a jejunal type of SCMT.
The cloning and characterization of slc5a12 (SMCT2) is reported.
slc5a8 (zeige SLC5A8 ELISA Kits) and slc5a12 in kidney in c/ebpdelta (zeige CEBPD ELISA Kits)-/- mice have a role in the renal handling of lactate and urate
These data provide the first evidence for the expression of SMCT1 (zeige SLC5A8 ELISA Kits) and SMCT2 in the retina and for the cell-type specific distribution of these transporters within the retina.
low-affinity transporter SMCT2 initiates lactate absorption in the early parts of the proximal tubule followed by the participation of the high-affinity transporter SMCT1 (zeige SLC5A8 ELISA Kits) in the latter parts of the proximal tubule.
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007
electroneutral sodium monocarboxylate cotransporter
, low-affinity sodium-lactate cotransporter
, sodium solute cotransporter
, sodium-coupled monocarboxylate transporter 2
, solute carrier family 5 member 12
, sodium-iodide related cotransporter
, solute carrier family 5 (sodium/glucose cotransporter), member 12