Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteine (SLC5A1)

SLC5A1 encodes a member of the sodium-dependent glucose transporter (SGLT) family. Zusätzlich bieten wir Ihnen Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Antikörper (113) und Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Kits (30) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLC5A1 6523 P13866
SLC5A1 20537 Q8C3K6
SLC5A1 25552 P53790
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$6,052.17
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$8,623.45
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$333.33
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Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
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SLC5A1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine) ,

Rat (Rattus)

Am meisten referenzierte Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteine

  1. Human SLC5A1 Protein expressed in Wheat germ - ABIN1320482 : Huang, Hsu, Huang, Chen, Hsiao, Zhang, Fidler, Hung: Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis. in American journal of translational research 2013 (PubMed)

Weitere Proteine zu Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartnern

Horse (Equine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartner

  1. SGLT1 expression is enhanced, with time, 2-fold in the duodenum and 3.3-fold in the ileum for horses switched, gradually over a 2-month period, from low (<1.0 g/kg bwt/day) to high hCHO (6.0 g/kg bwt/day) diets of known composition.

Human Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartner

  1. Homoeriodictyol affects both the glucose metabolism and the serotonin system in Caco-2 cells via a sodium glucose cotransporter 1 protein (SGLT-1)-meditated pathway.

  2. Binding of RS1 (zeige RS1 Proteine)-Reg (zeige EXTL3 Proteine) to ODC1 (zeige ODC1 Proteine) inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.

  3. JAK3 (zeige JAK3 Proteine) up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.

  4. Results found that SGLT1 is required for FLIPL induced cell aerobic glycolysis and survival to low glucose conditions. In patients with hepatocellular carcinoma, SGLT1 expression level was positively correlated with FLIPL expression level.

  5. Although the similarity between the pf values of SGLT1 and aquaporin-1 (zeige AQP1 Proteine) makes a transcellular pathway plausible, it renders water pumping physiologically negligible because the passive flux would be orders of magnitude larger.

  6. Compound K induces SGLT1 expression and glucose uptake in differentiated intestinal Caco-2 cells.

  7. Data demonstrate a role for Per1 (zeige PER1 Proteine) in the transcriptional regulation of NHE3 (zeige SLC9A3 Proteine) and SGLT1 in the kidney.

  8. Cardiac SGLTs, possibly SGLT1 in particular, appear to provide an important protective mechanism against ischemia-reperfusion injury by replenishing ATP stores in ischemic cardiac tissues.

  9. CREB (zeige CREB1 Proteine) activation is essential for EGF (zeige EGF Proteine)-induced SGLT1 gene expression.

  10. SGLT1 or GLUT2 (zeige SLC2A2 Proteine) interact with the cytoskeleton in the intestinal epithelium during hexose absorption.

Mouse (Murine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartner

  1. SGLT1 deficiency turns Listeria infection into a lethal disease in mice.

  2. sodium influx through cerebral SGLT-1 may exacerbate cerebral ischemia-induced neuronal damage

  3. JAK3 (zeige JAK3 Proteine) up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.

  4. Enhanced cerebral sodium-glucose transporter function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage.

  5. These findings support the involvement of SGLT1 in post-oral glucose and MDG (zeige CACNA1S Proteine) conditioning.

  6. Compound K upregulates SGLT1 expression in vivo in mice.

  7. Studied leptin (zeige LEP Proteine) and CST (zeige CORT Proteine) modulation of SGLT1 expression in hyperleptinemic type 2 diabetic mice.

  8. Cardiac knockdown of SGLT1 in a murine model of PRKAG2 (zeige PRKAG2 Proteine) cardiomyopathy attenuates the disease phenotype, implicating SGLT1 in the pathogenesis. Overexpression of SGLT1 causes pathologic cardiac hypertrophy and left ventricular failure that is reversible.

  9. In conclusion, SPAK (zeige STK39 Proteine) is a powerful negative regulator of SGLT1 protein abundance in the cell membrane and thus of electrogenic glucose transport.

  10. role of SGLT1 and GLUT2 (zeige SLC2A2 Proteine) in intestinal glucose transport and sensing

Pig (Porcine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartner

  1. the effects of Transmissible gastroenteritis virus infection on glucose uptake and SGLT1 and GLUT2 (zeige SLC2A2 Proteine) expression, are reported.

  2. Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90 (zeige HSP90 Proteine), CAT1 (zeige SLC7A1 Proteine), SGLT1 and GLUT4 (zeige SLC2A4 Proteine) increases in some tissues in pigs under chronic heat stress conditions.

  3. The segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity.

  4. The increased expression of SGLT1 in the jejunum by phytase supplementation implies that phytase alleviated the negative effects of phytic acid partly through increased expression of SGLT1.

  5. neonates have high intestinal apical SGLT1 uptake activity by abundantly expressing SGLT1 protein in epithelia and on apical membrane along the entire crypt-villus axis in association with enhanced protein translational control mechanisms in crypt cells.

  6. In accord with a rise in methyl alpha-D-glucopyranoside uptake activity, the mRNA and protein levels of SGLT1 were apparently up-regulated in the presence of apoE3

  7. Expression of SLGT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney.

Cow (Bovine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaktionspartner

  1. Na+-dependent glucose cotransporter(SGLT)1 mRNA was most abundant in bovine intestine, at intermediate levels in bovine kidney, and at lower levels in bovine mammary gland, liver, and lung.

Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Protein Überblick

Protein Überblick

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SLC5A1

  • solute carrier family 5 member 1 (SLC5A1)
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (slc5a1)
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (Slc5a1)
  • solute carrier family 5 member 1 (Slc5a1)
  • solute carrier family 5 member 10 (SLC5A10)
  • D22S675 Protein
  • NAGT Protein
  • Sglt1 Protein
  • SGLT5 Protein
  • SLC5A1 Protein
  • zgc:66074 Protein
  • zgc:85782 Protein

Bezeichner auf Proteinebene für SLC5A1

Na+/glucose co-transporter , sodium/glucose cotransporter 1 , SGLT1 , solute carrier family 5 (sodium/glucose cotransporter), member 1 , solute carrier family 5, member 1 , sodium/glucose cotransporter 1-like , Na+/glucose cotransporter 1 , high affinity sodium-glucose cotransporter , Na(+)/glucose cotransporter 1 , sodium glucose cotransporter 1 , sodium-glucose cotransporter 1 , solute carrier family 5 member 1 , solute carrier family 5, member alpha 1 , Na+/glucose cotransporter , Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter) , sodium-glucose cotransporter-like 1 , cortical sodium-D-glucose cotransporter , sodium/glucose cotransporter-like protein , SGLT-1 , Na(+)/glucose cotransporter 5 , sodium/glucose cotransporter 5 , solute carrier family 5 member 10

GENE ID SPEZIES
100033952 Equus caballus
393654 Danio rerio
458779 Pan troglodytes
717070 Macaca mulatta
100137235 Papio anubis
100435495 Pongo abelii
100593847 Nomascus leucogenys
6523 Homo sapiens
20537 Mus musculus
397113 Sus scrofa
25552 Rattus norvegicus
492299 Canis lupus familiaris
282361 Bos taurus
100009262 Oryctolagus cuniculus
492300 Ovis aries
395496 Gallus gallus
497235 Sus scrofa
Ausgewählte Anbieter für Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteine (SLC5A1)
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