Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 Proteine (SLC25A5)

SLC25A5 is a member of the mitochondrial carrier subfamily of solute carrier protein genes. Zusätzlich bieten wir Ihnen SLC25A5 Antikörper (26) und SLC25A5 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SLC25A5 11740 P51881
SLC25A5 292 P05141
SLC25A5 25176 Q09073
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Showing 5 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$318.85
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SLC25A5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,

Human , , ,
, ,
Rat (Rattus)

Weitere Proteine zu Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) Interaktionspartnern

Mouse (Murine) Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) Interaktionspartner

  1. Deficiency in the mouse mitochondrial ANT2 gene is associated with cardiac noncompaction.

  2. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  3. Erythroid and B-cell development may be particularly vulnerable to Ant2 depletion-mediated mitochondrial dysfunction and oxidative stress.

  4. Sirt4 (zeige SIRT4 Proteine) regulates ATP levels via ANT2 and a feedback loop involving AMPK (zeige PRKAA1 Proteine).

  5. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

  6. ANT2 and ANT1 (zeige SLC25A4 Proteine) regulate L1-mediated neurite outgrowth in conjunction with MMP14 (zeige MMP14 Proteine) at the plasma membrane.

  7. In liver only Ant2 mRNA was found, but in brown adipose tissue, Ant1 & Ant2 mRNA levels were equal. The ANT2 isoform may mediate fatty-acid-induced uncoupling.

  8. At high protonmotive force, an endogenously generated activator stimulates proton conductance catalysed partly by UCP3 and partly by the adenine nucleotide translocase.

Human Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) Interaktionspartner

  1. Findings suggest that ANT2 overexpression contributes to EGFR (zeige EGFR Proteine)-TKI resistance in non-small cell lung cancer.

  2. Study found that ANT2 was upregulated in sorafenibresistant hepatocellular carcinoma Huh7 cell line and its overexpression promoted sorafenib resistance.

  3. ANT2 shRNA downregulates miR (zeige MLXIP Proteine)-19a and miR (zeige MLXIP Proteine)-96 through the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway and suppresses tumor growth in hepatocellular carcinoma cells.

  4. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  5. TGF-beta (zeige TGFB1 Proteine)-mediated suppression of ANT2 through NF1 (zeige NF1 Proteine)/Smad4 (zeige SMAD4 Proteine) complexes contributes to oxidative stress and DNA damage during induction of cellular senescence.

  6. Sirt4 (zeige SIRT4 Proteine) regulates ATP levels via ANT2 and a feedback loop involving AMPK (zeige PRKAA1 Proteine).

  7. ANT2 suppression by shRNA may be able to exert anticancer effects in HCC (zeige FAM126A Proteine) further by restoring SOCS1 (zeige SOCS1 Proteine) expression

  8. SLC25A5 is involved in memory formation or establishment, which could add mitochondrial processes to the wide array of pathways that regulate normal cognitive functions.

  9. miR (zeige MLXIP Proteine)-636 might function as a tumor suppressor miRNA affecting hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) tumorigenesis via downregulation of Ras, and that ANT2 suppression by shRNA could exert an anticancer effect by restoring miR (zeige MLXIP Proteine)-636 expression in HCC (zeige FAM126A Proteine).

  10. Apigenin upregulates DR5 and enhances TRAIL induced apoptosis by binding and inhibiting ANT2.

SLC25A5 Protein Überblick

Protein Überblick

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.

Genbezeichner und Symbole assoziert mit SLC25A5

  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 L homeolog (slc25a5.L)
  • solute carrier family 25 member 5 (SLC25A5)
  • adenine nucleotide translocator 2 (LOC100301662)
  • solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 (Slc25a5)
  • solute carrier family 25 member 5 (Slc25a5)
  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (slc25a5)
  • ADP/ATP translocase 2-like (LOC709383)
  • 2F1 Protein
  • AAC2 Protein
  • ANT2 Protein
  • CHUNP6931 Protein
  • SI:bZ46J2.1 Protein
  • si:bz46j2.2 Protein
  • SI:bZ46J2.3 Protein
  • SI:bZ46J2.5 Protein
  • SI:bZ46J2.6 Protein
  • SI:bZ46J2.7 Protein
  • SI:bZ46J2.9 Protein
  • sr:nyz040 Protein
  • T2 Protein
  • T3 Protein
  • wu:fe06b05 Protein

Bezeichner auf Proteinebene für SLC25A5

adenine nucleotide translocator 2 , ADP,ATP carrier protein 2 , ADP/ATP translocase 2 , ANT 2 , adenine nucleotide translocase , adenine nucleotide translocator 2, fibroblast , solute carrier family 25 member 5 , adenine nucleotide translocator 2 (fibroblast) , ADP,ATP carrier protein, fibroblast isoform , ADP/ATP carrier protein , Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein) , Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein) , adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein) , adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein) , solute carrier family 25 alpha, member 5 , ADP/ATP translocase 2-like

GENE ID SPEZIES
380187 Xenopus laevis
100158185 Sus scrofa
100301662 Oncorhynchus mykiss
11740 Mus musculus
282479 Bos taurus
292 Homo sapiens
25176 Rattus norvegicus
192321 Danio rerio
709383 Macaca mulatta
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