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Sodium-ion independent, medium affinity carnitine transporter. Zusätzlich bieten wir Ihnen Solute Carrier Family 22 (Organic Anion Transporter), Member 9 Antikörper (10) und viele weitere Produktgruppen zu diesem Protein an.
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Pravastatin is the first identified OAT7 drug substrate. Substantial inter-individual variability in hepatic OAT7 expression, majorly driven by HNF4alpha (zeige HNF4A Proteine), may contribute to pravastatin drug disposition and might affect response.
uptake of steroid sulfates by isolated trophoblasts is mediated by OATP-B (zeige SLCO2B1 Proteine) and OAT-4 suggesting a physiological role of both carrier proteins in placental uptake of fetal-derived steroid sulfates.
Both progesterone and activation of PKC (zeige PRRT2 Proteine) inhibited hOAT4 activity through redistribution of the transporter from cell surface to the intracellular compartments.
OAT7 is the first liver-specific transporter (zeige SLC22A7 Proteine) among members of the organic anion transporters of SLC22 family.
The data provide a model for the concerted action of OAT1 (zeige KCNK3 Proteine) mediating apical secretion of glutarate derivatives from proximal tubule cells
The regulatory single nucleotide polymorphism (SNP) of OAT4 found in the promoter region of nephrectomized patients is unlikely to influence mRNA expression or promoter activity of OAT4.
Review summarizes current knowledge on the functional and phenotypic consequences of genetic variation in intestinally, hepatically and renally expressed members of solute carrier (zeige SERTAD2 Proteine) family (SLC22) member 9.
Functional differences in steroid uptake of SLC22A9 and SLC02B1 in human placenta are reported.
Human organic anion transporter (zeige SLC22A6 Proteine) hOAT4 is a transporter of perfluorooctanoic acid.
Sodium-ion independent, medium affinity carnitine transporter. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 746.
organic anion transporter 4
, organic anion transporter 7
, solute carrier family 22 (organic anion/cation transporter), member 9
, solute carrier family 22 member 9
, solute carrier family 22, member 25