Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Proteine (SCN7A)

SCN7A encodes one of the many voltage-gated sodium channel proteins. Zusätzlich bieten wir Ihnen Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Antikörper (39) und Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus SCN7A SCN7A 20272  
Ratte SCN7A SCN7A 64155  
SCN7A 6332 Q01118
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Top Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Proteine auf antikoerper-online.de

Showing 4 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details

SCN7A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,

Weitere Proteine zu Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Interaktionspartnern

Mouse (Murine) Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Interaktionspartner

  1. These results suggest that the Na(+) signal generated in Nax-positive glial cells leads to the activation of TRPV4 (zeige TRPV4 Proteine)-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.

  2. SAP97 (zeige DLG1 Proteine) promotes the stability of Nax channels at the plasma membrane.

  3. Nax/Nav2 channel is expressed in alveolar type II cells, suggesting a role in the control of extracellular sodium level.

  4. Nav2-deficient mice show a preference for 0.15 M NaCl over water during a free two-choice intake test compared with wild-type; preference ratios for NaCl in wild tend to increase after combined superior laryngeal and glossopharyngeal nerve transection.

  5. identified the promoter and transcription start sites of Na(x) sodium channel in dorsal root ganglia neurons; findings provide the basis with which to understand tissue-specific regulation of Nax sodium channel gene (Scn7a) expression

Human Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Interaktionspartner

  1. The authors demonstrated that the sodium channel Nax functions as a sodium sensor. With increased extracellular sodium, Nax up-regulates prostasin (zeige PRSS8 Proteine), which results in activation of the sodium channel ENaC (zeige SCNN1A Proteine).

  2. SNP rs7565062 of SCN7A was significantly associated with essential hypertension in a Northern Han Chinese population

Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Protein Überblick

Protein Überblick

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Genbezeichner und Symbole assoziert mit SCN7A

  • sodium channel, voltage-gated, type VII, alpha (Scn7a)
  • sodium voltage-gated channel alpha subunit 7 (Scn7a)
  • sodium voltage-gated channel alpha subunit 7 (SCN7A)
  • 1110034K09Rik Protein
  • AI642000 Protein
  • Na-G Protein
  • NaG Protein
  • Nav2 Protein
  • Nav2.1 Protein
  • Nav2.2 Protein
  • Nav2.3 Protein
  • Nax Protein
  • SCN6A Protein

Bezeichner auf Proteinebene für SCN7A

sodium channel, voltage-gated, type VI, alpha polypeptide , sodium channel, voltage-gated, type VII, alpha polypeptide , sodium channel protein type 7 subunit alpha , sodium channel voltage-gated type VI alpha polypeptide , sodium channel, voltage-gated, type 6, alpha polypeptide , putative voltage-gated sodium channel subunit alpha Nax , sodium channel protein cardiac and skeletal muscle subunit alpha , sodium channel protein type VII subunit alpha , voltage-dependent sodium channel alpha subunit

GENE ID SPEZIES
20272 Mus musculus
64155 Rattus norvegicus
6332 Homo sapiens
100516881 Sus scrofa
507516 Bos taurus
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