anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Antikörper

SHOC2 encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus SHOC2 SHOC2 56392 O88520
Anti-Ratte SHOC2 SHOC2 309548 Q6AYI5
Anti-Human SHOC2 SHOC2 8036 Q9UQ13
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Top anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: SHOC2 Sample Tissue: Human Fetal Kidney Antibody Dilution: 1ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>Host: </b>Rabbit<br><b>Target Name: </b>SHOC2<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: SUR-8 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. Western Blot: SUR-8 Antibody  - Analysis in human cell line Daudi. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB SHOC2 Antibody (N-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow). SHOC2 Antibody (N-term)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$474.10
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$350.00
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$376.44
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

Am meisten referenzierte anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) Antikörper

  1. Human Polyclonal SHOC2 Primary Antibody für ICC, IF - ABIN4356990 : Yi, Chen, Wu, Yang, Xu, Zhuang, Han, Xu: Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development. in Developmental dynamics : an official publication of the American Association of Anatomists 2010 (PubMed)

Weitere Antikörper gegen Soc-2 Suppressor of Clear Homolog (C. Elegans) Interaktionspartner

Mouse (Murine) Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Interaktionspartner

  1. Results provide evidence that SHOC2 trapping at different subcellular sites has a diverse impact on ERK (zeige EPHB2 Antikörper) signaling strength and dynamics, suggesting a dual counteracting modulatory role of SHOC2 in the control of ERK (zeige EPHB2 Antikörper) signaling exerted at different intracellular compartments.

  2. Data suggest that SUR-8 may act in an ERK (zeige EPHB2 Antikörper)-independent pathway to regulate AVC development.

  3. Erbin (zeige ERBB2IP Antikörper) has a regulatory role in the Ras-Raf (zeige RAF1 Antikörper)-MEK (zeige MDK Antikörper) pathway and may inhibit ERK (zeige EPHB2 Antikörper) activation by disrupting the Sur-8-Ras/Raf (zeige RAF1 Antikörper) interaction

Human Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Interaktionspartner

  1. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of colorectal cancer (CRC (zeige CALR Antikörper)) cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC (zeige CALR Antikörper) cells.

  2. Results provide evidence that SHOC2 trapping at different subcellular sites has a diverse impact on ERK (zeige EPHB2 Antikörper) signaling strength and dynamics, suggesting a dual counteracting modulatory role of SHOC2 in the control of ERK (zeige EPHB2 Antikörper) signaling exerted at different intracellular compartments.

  3. results demonstrate that PSMC5 (zeige PSMC5 Antikörper) is a new and important player involved in regulating ERK1/2 signal transmission through the remodeling of Shoc2 scaffold complex in a spatially-defined manner.

  4. Noonan-like syndrome has been related to the invariant c.4A > G missense change in SHOC2.

  5. Two unrelated Taiwanese patients have been described with Noonan-like syndrome with loose anagen hair who also have moyamoya disease and in whom heterozygous germline mutation in SHOC2 was found.

  6. ectopic overexpression of human Shoc2 in PC12 cells significantly promotes neurite extension in the presence of Epidermal Growth Factor (zeige EGF Antikörper), a stimulus that induces proliferation rather than differentiation in these cells.

  7. Extreme phenotypic variability associated with the invariant SHOC2 c.4A>G (p.Ser2Gly) missense mutation in Noonan-like syndrome with loose anagen hair.

  8. A newborn heterozygous for the invariant c.4A>G missense change in SHOC2.

  9. Data show that both Shoc2 and HUWE1 (zeige HUWE1 Antikörper) are necessary to control the levels and ubiquitination of the Shoc2 signaling partner, RAF-1 (zeige RAF1 Antikörper).

  10. Both MRAS (zeige MRAS Antikörper) and SHOC2 play a key role in polarized migration.

Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Antigen-Profil

Protein Überblick

This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.

Genbezeichner und Symbole assoziert mit SHOC2

  • soc-2 (suppressor of clear) homolog (C. elegans) (Shoc2) Antikörper
  • SHOC2 leucine-rich repeat scaffold protein (Shoc2) Antikörper
  • SHOC2 leucine-rich repeat scaffold protein S homeolog (shoc2.S) Antikörper
  • SHOC2, leucine rich repeat scaffold protein (SHOC2) Antikörper
  • SHOC2 leucine-rich repeat scaffold protein (shoc2) Antikörper
  • AU017287 Antikörper
  • mKIAA0862 Antikörper
  • si:ch211-159c12.3 Antikörper
  • si:ch211-197i12.3 Antikörper
  • SIAA0862 Antikörper
  • SOC2 Antikörper
  • SUR8 Antikörper
  • zgc:152956 Antikörper

Bezeichner auf Proteinebene für SHOC2

Ras-binding protein SUR-8 , leucine-rich repeat protein SHOC-2 , protein soc-2 homolog , protein sur-8 homolog , suppressor of clear, C. elegans, homolog of , Protein soc-2 homolog , Protein sur-8 homolog

GENE ID SPEZIES
56392 Mus musculus
309548 Rattus norvegicus
380042 Xenopus laevis
8036 Homo sapiens
511417 Bos taurus
423894 Gallus gallus
477819 Canis lupus familiaris
555476 Danio rerio
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