anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) Antikörper

Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Zusätzlich bieten wir Ihnen SNRNP70 Proteine (8) und SNRNP70 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SNRNP70 20637 Q62376
SNRNP70 361574  
SNRNP70 6625 P08621
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Top anti-SNRNP70 Antikörper auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-SNRP70 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 WB Suggested Anti-SNRP70 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 Positive Control: HepG2 cell lysate SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-SNRP70 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate SNRNP70 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using SNRNP70 antibody (ABIN5973598) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat liver using SNRNP70 antibody (ABIN5973598) at dilution of 1/100 (40x lens). 100 μL 11 bis 16 Tage
$426.40
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using SNRNP70 antibody. Immunohistochemistry of paraffin-embedded rat liver using SNRNP70 antibody. 100 μL 13 bis 14 Tage
$393.25
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$507.83
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$581.17
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using SNRNP70 antibody (ABIN1877092) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s. 100 μL 11 bis 13 Tage
$366.77
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details

Am meisten referenzierte anti-SNRNP70 Antikörper

  1. Cow (Bovine) Polyclonal SNRNP70 Primary Antibody für IHC, WB - ABIN2778829 : Dieker, Cisterna, Monneaux, Decossas, van der Vlag, Biggiogera, Muller: Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K. in Cell death and differentiation 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal SNRNP70 Primary Antibody für IHC, IHC (p) - ABIN4891514 : Nakaya, Alexiou, Maragkakis, Chang, Mourelatos: FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns. in RNA (New York, N.Y.) 2013 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal SNRNP70 Primary Antibody für IHC, WB - ABIN2778715 : Zhang, Walker, Tamplin, Rossant, Stanford, Hughes: Zfp206 regulates ES cell gene expression and differentiation. in Nucleic acids research 2006 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen SNRNP70 Interaktionspartner

Zebrafish Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) Interaktionspartner

  1. These findings provide evidence for a new role of a general small nuclear ribonucleoprotein particle protein, U1C, as a mediator of alternative splicing regulation.

Mouse (Murine) Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) Interaktionspartner

  1. This splice-switching class of molecules is the first to specifically correct the ELP1 exon 20 splicing defect. Our data provide proof of principle of ExSpeU1s-adeno-associated virus particles as a novel therapeutic strategy for FD.

Human Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) Interaktionspartner

  1. These results indicate that the galectin-3-U1 snRNP-pre-mRNA ternary complex is a functional E complex and that U1 snRNP is required to assemble galectin-3 onto an active spliceosome

  2. The epitopes of U1-70K autoantibodies have been mapped at single-amino acid resolution.

  3. The authors propose that Gemin2 is a versatile hub for ribonucleoprotein exchange that functions broadly in RNA metabolism.

  4. data lead to a model that FUS functions in coupling transcription to splicing via mediating an interaction between RNAP II and U1 snRNP

  5. The selection of 5'-splice site nucleotides by U1 snRNP is achieved predominantly through basepairing with U1 snRNA whilst U1-C fine-tunes relative affinities of mismatched 5'-splice sites.

  6. methylation of snRNP70 by SETMAR regulates constitutive and/or alternative splicing

  7. U1-70K interacts with the SMN complex and is required for nuclear gem integrity.

  8. Data indicate that small nuclear ribonucleoprotein U1-70K in Alzheimer disease (AD) may directly sequester normal soluble forms of U1-70K into insoluble aggregates.

  9. [review] The presence of antibodies against U1snRNP autoantigen is considered the serological hallmark of mixed connective tissue disease (MCTD), which is characterized by overlapping features between at least two systemic autoimmune diseases.

  10. These studies identify U1 snRNP pathologic changes in brain of early onset genetic forms of Alzheimer's disease

  11. inhibition of U1 snRNP also leads to regulation of the usage of In3 pA, suggesting that the C/P activity in the cell can be cross-regulated by splicing, leading to coordination between these two processes.

  12. High expression of U1-70K and other U1 small nuclear ribonucleoproteins spliceosome proteins in Alzheimer's disease patients and those with mild cognitive impairment.

  13. Serum antibodies against the 70k polypeptides of the U1 ribonucleoprotein complex are associated with psychiatric syndromes in systemic lupus erythematosus.

  14. U1-snRNP activates the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in CD14+ human monocytes dependently of anti-U1-snRNP Abs, leading to interleukin (IL)-1beta production.

  15. data identify some fungal proteins as possible triggers of anti-U1-70 kDa autoimmunity via molecular mimicry.

  16. the hypo-phosphorylated RS domain of SRSF1 interacts with its own RRM, thus competing with U1-70K binding, whereas the hyper-phosphorylated RS domain permits the formation of a ternary complex containing ESE, an SR protein, and U1 snRNP

  17. Recruitment of RNAPII, U1-70K and ASF/SF2 protein to transcription sites is splicing independent.

  18. crucial association of B19-NS1 in development of autoimmunity by inducing apoptosis and specific cleavage of 70 kDa U1-snRNP

  19. U1-70k isoforms control subunit dynamics in the human spliceosomal U1 snRNP

SNRNP70 Antigen-Profil

Protein Überblick

Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.

Genbezeichner und Symbole assoziert mit SNRNP70

  • small nuclear ribonucleoprotein, U1 70kDa subunit (snrnp70) Antikörper
  • small nuclear ribonucleoprotein U1 subunit 70 (SNRNP70) Antikörper
  • small nuclear ribonucleoprotein 70 (U1) (snrnp70) Antikörper
  • small nuclear ribonucleoprotein 70 (U1) (Snrnp70) Antikörper
  • small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70) Antikörper
  • small nuclear ribonucleoprotein, U1 70kDa subunit L homeolog (snrnp70.L) Antikörper
  • 70kDa Antikörper
  • 2700022N21Rik Antikörper
  • 3200002N22Rik Antikörper
  • AI325098 Antikörper
  • R74807 Antikörper
  • RNPU1Z Antikörper
  • Rnulp70 Antikörper
  • RPU1 Antikörper
  • Snp1 Antikörper
  • Snrp70 Antikörper
  • Srnp70 Antikörper
  • U1-70 Antikörper
  • U1-70K Antikörper
  • U1AP Antikörper
  • U1RNP Antikörper
  • U170K Antikörper
  • wu:fc20b04 Antikörper
  • zgc:136450 Antikörper

Bezeichner auf Proteinebene für SNRNP70

U1 small nuclear ribonucleoprotein 70 kDa , U1 snRNP 70 kDa , U1-70K , small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen) , small nuclear ribonucleoprotein 70kDa (U1) , U1 small nuclear ribonucleoprotein polypeptide A , U1 small ribonucleoprotein 70kd , small nuclear ribonucleoprotein 70kDa , U1 small nuclear ribonucleoprotein 70 kDa polypeptide A

GENE ID SPEZIES
493488 Xenopus (Silurana) tropicalis
747202 Pan troglodytes
100595176 Nomascus leucogenys
445398 Danio rerio
20637 Mus musculus
361574 Rattus norvegicus
397946 Xenopus laevis
6625 Homo sapiens
484388 Canis lupus familiaris
535113 Bos taurus
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