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SGTA encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Zusätzlich bieten wir Ihnen Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.
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Coimmunoprecipitation studies indicated that non-glycosylated tetherin (zeige BST2 Antikörper) is stabilized through the formation of a ternary SGTA/Vpu/tetherin (zeige BST2 Antikörper) complex. Although the results do not provide support for a physiological function of SGTA in HIV-1 replication, they demonstrate that SGTA overexpression regulates tetherin (zeige BST2 Antikörper) expression and stability, thus providing insights into the function of SGTA in endoplasmic reticulum translocation
study demonstrates a critical role of Hsc70 (zeige HSPA8 Antikörper) in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA controls Hsc70 (zeige HSPA8 Antikörper) to impact this process
the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.
data suggest that SGTA regulates the cellular fate of a range of hydrophobic polypeptides should they become exposed to the cytosol.
Data show that molecular chaperone (zeige HSP90AA1 Antikörper) BAG6_ubiquitin-like domain (UBL) and ubiquitin-like 4A (zeige UBL4A Antikörper) UBL4A_UBL compete for the same binding site on N-terminal dimerisation domain of SGTA protein (SGTA_NT).
SGTA overexpression may be involved in the pathogenesis of breast cancer which might serve as a future target for novel treatment in breast cancer.
Our data suggest a role for SGTA at distinct steps in the chaperone-dependent modulation of androgen, glucocorticoid, and progesterone receptor (zeige PGR Antikörper) activity.
SGTA depletion decreased cyclin A (zeige CCNA2 Antikörper) and cyclin B levels.
A role of SGTA in Non-Hodgkin's lymphoma (NHL (zeige RTEL1 Antikörper)) cell proliferation, adhesion and drug resistance, and it may pave the way for a novel therapeutic approach for cell adhesion-mediated drug resistance in NHL (zeige RTEL1 Antikörper).
High expression of SGTA in esophageal squamous cell carcinoma correlates with proliferation and poor prognosis.
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein\; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
, small glutamine-rich tetratricopeptide
, small glutamine-rich tetratricopeptide repeat-containing protein beta
, small glutamine-rich tetratricopeptide repeat-containing protein alpha
, protein containing three tetratricopeptide repeats
, vpu-binding protein
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein
, small glutamine-rich protein with tetratricopeptide repeats 1
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein (SGT)