Sialic Acid Binding Ig-Like Lectin 5 Proteine (SIGLEC5)

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. Zusätzlich bieten wir Ihnen SIGLEC5 Antikörper (166) und SIGLEC5 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIGLEC5 8778 O15389
SIGLEC5 83382 Q91Y57
Ratte SIGLEC5 SIGLEC5 292843  
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Top SIGLEC5 Proteine auf antikoerper-online.de

Showing 10 out of 19 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,649.05
Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
HEK-293 Cells Human Fc Tag Human Siglec-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
CHO Cells Human Fc Tag   25 μg Anmelden zum Anzeigen 10 bis 12 Tage
$220.26
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$554.07
Details
Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$560.00
Details
HEK-293 Cells Human Fc Tag   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$554.33
Details

SIGLEC5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , , ,
Mouse (Murine)
,

Weitere Proteine zu Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartnern

Human Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartner

  1. An unbiased screen revealed Hsp70 (zeige HSP70 Proteine) as a ligand for Siglec-5 and Siglec-14 (zeige SIGLEC14 Proteine). Hsp70 (zeige HSP70 Proteine) stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 (zeige SIGLEC14 Proteine) is pro-inflammatory.

  2. Data indicate that the Siglec-5/14 genotype influences neutrophil responses to group B Streptococcus.

  3. we found that secretory IgA is taken up by M cells via the Dectin-1 (zeige CLEC7A Proteine) receptor, with the possible involvement of Siglec-5 acting as a co-receptor.

  4. These studies demonstrate the Siglec5 carbohydrate recognition domain alone is sufficient for binding sialylated carbohydrates and provide a foundation for further investigation of Siglec5 structure and function.

  5. Siglec-5 expression protects T cells from HIV-1- and apoptosis-induced cell death and contributes to the different outcomes of HIV-1 infection in humans and chimpanzees.

  6. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein.

  7. Siglec-5 expression correlates with lack of proliferation in a subset of human cells, and is upregulated by activation of chimpanzee but not human lymphocytes.

  8. expression of Siglec-5 on cells of the myelomonocytic lineage and alteration of its expression by inflammatory stimuli suggest a role for this protein in cell/cell interactions following microbial exposure.

  9. Siglec-5 can be classified as an inhibitory receptor with the potential to mediate SHP-1 and/or SHP-2-dependent signaling in the absence of tyrosine phosphorylation.

  10. Siglecs-5 did not interact with sulfate derivatives of LacNAc and sulfated (zeige SULF1 Proteine) oligosaccharides containing sialic acid.

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartner

  1. The Siglec-E-deficient dendritic cells were defective for TRIF (zeige RNF138 Proteine)-mediated IFN-beta (zeige IFNB1 Proteine) production in response to E. coli infection.

  2. This study demonstrated that virulent parasite Leishmania donovani (AG83+Sias) establish a unique sialic acids-mediated binding and subsequent phagocytosis in the host cell through the selective exploitation of siglec-1 (zeige SIGLEC1 Proteine).

  3. new data relating to the structure and function of Siglec-E, the major CD33 (zeige CD33 Proteine)-related Siglec expressed on mouse neutrophils, monocytes, macrophages, and dendritic cells.

  4. indicate that Siglec-9 (zeige SIGLEC9 Proteine) affects several different signaling pathways in IL-4 (zeige IL4 Proteine)-stimulated macrophages, which resulted in enhanced induction of Arg1 (zeige ARG1 Proteine) in Siglec-9 (zeige SIGLEC9 Proteine)-expressing RAW264 cells

  5. Competitive ELISA assays confirmed the involvement of sulfated (zeige SULF1 Proteine) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  6. Data indicate a role for neuraminidase 1 (Neu1 (zeige NEU1 Proteine)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (zeige TLR4 Proteine)) interaction and endotoxemia.

  7. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (zeige CD33 Proteine)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  8. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (zeige NOX1 Proteine) activation and ROS (zeige ROS1 Proteine) production

  9. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (zeige MUC1 Proteine)-expressing tumor in the transgenic mice.

  10. Siglec-9 (zeige SIGLEC9 Proteine) expressed on immune cells may play a role as a potential counterreceptor for MUC1 (zeige MUC1 Proteine) and that this signaling may be another MUC1 (zeige MUC1 Proteine)-mediated pathway and function in parallel with a growth factor-dependent pathway.

SIGLEC5 Protein Überblick

Protein Überblick

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Genbezeichner und Symbole assoziert mit SIGLEC5

  • sialic acid binding Ig like lectin 5 (SIGLEC5)
  • sialic acid binding Ig-like lectin E (Siglece)
  • sialic acid-binding Ig-like lectin 5 (LOC100597560)
  • sialic acid binding Ig-like lectin 5 (Siglec5)
  • CD33L2 Protein
  • Cd170 Protein
  • mSiglec-E Protein
  • OB-BP2 Protein
  • OBBP2 Protein
  • SIGLEC-5 Protein
  • Siglec5 Protein
  • Siglec9 Protein
  • Siglec12 Protein
  • Siglecl1 Protein

Bezeichner auf Proteinebene für SIGLEC5

CD33 antigen-like 2 , OB-binding protein 2 , obesity-binding protein 2 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding immunoglobulin-like lectin 5 , MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-5 , siglec-E , siglec-L1

GENE ID SPEZIES
8778 Homo sapiens
83382 Mus musculus
100597560 Nomascus leucogenys
292843 Rattus norvegicus
Ausgewählte Anbieter für SIGLEC5 Proteine (SIGLEC5)
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