Sialic Acid Binding Ig-Like Lectin 5 Proteine (SIGLEC5)

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. Zusätzlich bieten wir Ihnen SIGLEC5 Antikörper (174) und SIGLEC5 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SIGLEC5 8778 O15389
Ratte SIGLEC5 SIGLEC5 292843  
SIGLEC5    
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top SIGLEC5 Proteine auf antikoerper-online.de

Showing 10 out of 20 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Human Cells Human Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
CHO Cells Human Fc Tag   25 μg Anmelden zum Anzeigen 10 bis 12 Tage
$220.26
Details
Baculovirus infected Insect Cells Human hIgG-His-tag 0.5 mg Anmelden zum Anzeigen 13 bis 16 Tage
$1,230.77
Details
HEK-293 Cells Human Fc Tag Human Siglec-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$560.00
Details
HEK-293 Cells Human Fc Tag   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details

SIGLEC5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, , , , , ,
Mouse (Murine)
,

Weitere Proteine zu Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartnern

Human Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) Interaktionspartner

  1. PSGL1 (zeige SELPLG Proteine) and Siglec-5 are in close proximity at the leukocyte surface.SPSGL1 is a ligand for Siglec-5 and interacts with Siglec-5 ectodomain.Siglec-5 plays a role in PSGL1 (zeige SELPLG Proteine)-mediated leukocyte rolling and the inflammatory response in general.

  2. An unbiased screen revealed Hsp70 (zeige HSP70 Proteine) as a ligand for Siglec-5 and Siglec-14 (zeige SIGLEC14 Proteine). Hsp70 (zeige HSP70 Proteine) stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 (zeige SIGLEC14 Proteine) is pro-inflammatory.

  3. Data indicate that the Siglec-5/14 genotype influences neutrophil responses to group B Streptococcus.

  4. we found that secretory IgA is taken up by M cells via the Dectin-1 (zeige CLEC7A Proteine) receptor, with the possible involvement of Siglec-5 acting as a co-receptor.

  5. These studies demonstrate the Siglec5 carbohydrate recognition domain alone is sufficient for binding sialylated carbohydrates and provide a foundation for further investigation of Siglec5 structure and function.

  6. Siglec-5 expression protects T cells from HIV-1- and apoptosis-induced cell death and contributes to the different outcomes of HIV-1 infection in humans and chimpanzees.

  7. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA) have separate binding sites in streptococcal beta protein.

  8. Siglec-5 expression correlates with lack of proliferation in a subset of human cells, and is upregulated by activation of chimpanzee but not human lymphocytes.

  9. expression of Siglec-5 on cells of the myelomonocytic lineage and alteration of its expression by inflammatory stimuli suggest a role for this protein in cell/cell interactions following microbial exposure.

  10. Siglec-5 can be classified as an inhibitory receptor with the potential to mediate SHP-1 and/or SHP-2-dependent signaling in the absence of tyrosine phosphorylation.

SIGLEC5 Protein Überblick

Protein Überblick

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Genbezeichner und Symbole assoziert mit SIGLEC5

  • sialic acid binding Ig like lectin 5 (SIGLEC5)
  • sialic acid-binding Ig-like lectin 5 (LOC100597560)
  • sialic acid binding Ig-like lectin 5 (Siglec5)
  • CD33L2 Protein
  • CD170 Protein
  • OB-BP2 Protein
  • OBBP2 Protein
  • SIGLEC-5 Protein

Bezeichner auf Proteinebene für SIGLEC5

CD33 antigen-like 2 , OB-binding protein 2 , obesity-binding protein 2 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding immunoglobulin-like lectin 5 , sialic acid binding Ig-like lectin 5

GENE ID SPEZIES
8778 Homo sapiens
100597560 Nomascus leucogenys
292843 Rattus norvegicus
Ausgewählte Anbieter für SIGLEC5 Proteine (SIGLEC5)
Haben Sie etwas anderes gesucht?