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The product of MST4 is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. Zusätzlich bieten wir Ihnen Serine/threonine-Protein Kinase MST4 Antikörper (57) und und viele weitere Produktgruppen zu diesem Protein an.
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Findings reveal a mechanism by which TRAF6 (zeige TRAF6 Proteine) is regulated and highlight a role for MST4 in limiting inflammatory responses.
Our work describes an MST4-ATG4B (zeige ATG4B Proteine) signaling axis that influences glioblastoma autophagy and malignancy
Low MST-4 expression is associated with Graves' disease.
these data identify the MST4 kinase as a novel candidate to mediate human pituitary tumorigenesis in a hypoxic environment and position it as a potential therapeutic target.
Our results suggest that MST4, STK25 (zeige STK25 Proteine) and PDCD10 (zeige PDCD10 Proteine) are upregulated in prostate cancer and may play roles in prostate tumorigenesis. MST4 may be a helpful marker for identifying prostate cancer.
This study describes the key role of MST4 in facilitating the epithelial-mesenchymal transition process in hepatocellular carcinoma
Mutation of this residue was sufficient to switch the phosphorylation site preference for multiple kinases, including the serine-specific kinase PAK4 (zeige PAK4 Proteine) and the threonine-specific kinase MST4.
CCM3 (zeige PDCD10 Proteine) forms a stable complex with MST4 in vivo to promote cell proliferation and migration synergistically in a manner dependent on MST4 kinase activity.
In this review, the germinal center kinase (zeige MAP4K2 Proteine) III subfamily of mammalian Ste20 (zeige STK24 Proteine) (sterile 20)-like group of serine/threonine protein kinases comprises Ste20-like (zeige STK25 Proteine)/oxidant-stress-response kinase 1, MST3 (zeige STK24 Proteine) mammalian Ste20-like kinase 3 (zeige STK24 Proteine) and MST4.
crystal of the CCM3 (zeige PDCD10 Proteine)-MST4 C-terminal domain complex belonged to space group P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters a = 69.10, b = 69.10, c = 117.57 A
The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
, Mst3 and SOK1-related kinase
, STE20-like kinase MST4
, mammalian STE20-like protein kinase 4
, serine/threonine protein kinase MST4
, serine/threonine-protein kinase MST4
, mammalian Ste20-like protein kinase 4
, mammalian sterile 20-like 4
, serine/threonine-protein kinase MASK