anti-Septin 4 (SEPT4) Antikörper

SEPT4 is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Zusätzlich bieten wir Ihnen Septin 4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SEPT4 287606  
SEPT4 5414 O43236
SEPT4 18952 P28661
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Top anti-Septin 4 Antikörper auf antikoerper-online.de

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-SEPT4 Titration:  0.2-1 ug/ml  Positive Control:  Human cerebellum Human Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€255.75
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
€380.39
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Rind (Kuh) Ziege Unkonjugiert EIA, WB AP22419PU-N ARTS antibody staining of Human Heart lysate at 1µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
€345.58
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Fledermaus Ziege Unkonjugiert ELISA, IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
€428.32
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Hund Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
€488.35
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Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
€540.27
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Human Ziege Unkonjugiert EIA, WB AP22420PU-N ARTS antibody staining of Human Cerebellum lysate at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
€345.58
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: Septin-4 Antibody [NBP1-90093] - Staining of human cell line Hep G2 shows positivity in nucleus but excluded from the nucleoli. Antibody staining is shown in green. Immunohistochemistry-Paraffin: Septin-4 Antibody [NBP1-90093] Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells and cells in molecular layer. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
€437.50
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: Septin-4 Antibody [NBP1-90094] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue Immunohistochemistry-Paraffin: Septin-4 Antibody [NBP1-90094] - Staining of human cerebellum shows moderate cytoplasmic positivity in cells in granular layer and distinctly stained neuropil. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
€437.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: Septin-4 Antibody [NBP1-02711] - Staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Immunohistochemistry-Paraffin: Septin-4 Antibody [NBP1-02711] - Staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg Anmelden zum Anzeigen 10 bis 13 Tage
€495.00
Details

Am meisten referenzierte anti-Septin 4 Antikörper

  1. Human Polyclonal SEPT4 Primary Antibody für IHC (p), WB - ABIN541191 : Paavola, Horelli-Kuitunen, Palotie, Peltonen: Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. in Genomics 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SEPT4 Primary Antibody für FACS, IHC (p) - ABIN1944842 : Garcia, Rodrigues, de Oliveira Neto, de Araújo, Polikarpov, Tanaka, Tanaka, Garratt: The stability and aggregation properties of the GTPase domain from human SEPT4. in Biochimica et biophysica acta 2008 (PubMed)

  3. Human Polyclonal SEPT4 Primary Antibody für ELISA, WB - ABIN4352732 : Lhuillier, Rode, Escalier, Lorès, Dirami, Bienvenu, Gacon, Dulioust, Touré: Absence of annulus in human asthenozoospermia: case report. in Human reproduction (Oxford, England) 2009 (PubMed)

Weitere Antikörper gegen Septin 4 Interaktionspartner

Human Septin 4 (SEPT4) Interaktionspartner

  1. carnosic acid induces parkin by enhancing the ubiquitination of ARTS, leading to induction of XIAP.

  2. In this review, we will discuss the recent advances of the tauopathy research, primarily focusing on its association with the early axonal manifestation of axonal transport defect, axonal mitochondrial stress, autophagic vesicle accumulation and the proceeding of axon destruction, and the pathogenic Tau spreading across the synapse.

  3. Septin4 is a novel essential factor involved in oxidative stress induced vascular endothelial cell injury by interacting with apoptosis-related protein PARP1.

  4. The data suggest that Sept4_i1 induces hepatic stellate cell apoptosis by inhibiting Akt and Bcl-2 expression and up-regulating PPAR-gamma expression.

  5. results suggest that Septin4 may be involved in the process of activation of hepatic stellate cells by lipopolysaccharide stimulation.

  6. Bradeion/SEPT4 transcript levels are significantly increased in patients with transitional cell bladder cancer.We hypothesize that Bradeion is directly involved in bladder cancer pathogenesis with the highest expression at early cancer stages.

  7. Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS.

  8. these data suggests a tumor suppressor role of SEPT4_i1 in HCC through regulating hepatocellular carcinoma cell apoptosis.

  9. SEPT4 is a Notch target gene.

  10. The expression of SEPT4 is significantly decreased in the ejaculated sperm of idiopathic asthenozoospermia patients.

  11. ARTS is localized at mitochondria and promotes programmed cell death (apoptosis).

  12. role of Bradeion in colorectal neoplasms

  13. Sept4 is involved in the formation of cytoplasmic inclusions as well as induction of cell death in alpha-synuclein-associated neurodegenerative disorders.

  14. Data suggest that ARTS induces apoptosis by antagonizing IAPs, including XIAP.

  15. SEPT8 and SEPT4 are localized surrounding alpha-granules. Activation of platelets by agonists resulted in the translocation of SEPT4 and SEPT8 to the platelet surface indicating a possible functional role of these proteins in platelet granular secretion

  16. ARTS can function as a tumor suppressor protein in childhood acute lymphocytic leukemia.

  17. We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system.

  18. high cellular levels of ARTS protein sensitize cells toward apoptosis

  19. The data presented here suggest that ARTS P-loop is not frequently mutated in gastric, lung, and hepatocellular carcinomas, and that apoptosis deregulation in cancers is not dependent on the mutation of ARTS gene.

  20. Finds somatic mutation in P-loop domains of proapoptotic ARTS genes uncommon in colon cancers.

Mouse (Murine) Septin 4 (SEPT4) Interaktionspartner

  1. Adenovirus-Sept4 can attenuate the development of liver fibrosis induced by S. japonicum through apoptosis.

  2. The inhibition of the expression of the SEPT4 by praziquantel might be due to alleviation of the inflammatory response at the chronic and advanced stage of S. japonicum infection.

  3. The hypothetical pathogenicity by the chronic overload of SEPT4 alone, if any, is insufficient to trigger neurodegenerative process in the mouse brain.

  4. Sept4/ARTS(-/-) mice display marked improvement in wound healing and regeneration of hair follicles.

  5. Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS.

  6. Report SEPT4/5/7 expression in mouse cochlea and roles in auditory function.

  7. Sept4 and alpha-SMA may interact together in hepatic stellate cells (HSCs). Sept4 seems to be involved in the formation of inflammatory granulomata and subsequent liver fibrosis by regulating HSCs activation.

  8. ARTS (Septin 4) promotes apoptosis mainly through binding and antagonizing XIAP.

  9. Loss of Sept4 is associated with myofibroblastic transformation of hepatic stellate cells and results in liver fibrosis.

  10. Findings suggest that Sept4-null mice develop malignancies due to increased resistance of their HSPCs to apoptosis.

  11. These results suggest that Sept14 is involved in neuronal migration in cerebral cortex via interaction with Sept4.

  12. On Sept4(-/-) sperm, domain confinement was lost, and basigin localized over the entire plasma membrane.

  13. M-Septin is a novel mitochondrial septin that interacts with CRMP/CRAM in developing neurons.

  14. Cortical organization based on circular assembly of the septin cytoskeleton is essential for the structural and mechanical integrity of mammalian spermatozoa.

  15. Sept4 proteins play distinct but evolutionarily conserved functions in different cellular compartments.

  16. hepatic stellate cell-specific septin subunit Sept4 and perhaps the septin system are involved in the suppressive modulation of myofibroblastic transformation and fibrogenesis associated with liver diseases

  17. The interaction of DNAJB13 with SEPT4 in vitro and its spatiotemporal association with the annulus during sperm flagellum development suggest that DNAJB13 may be involved in assembling the annulus structure.

Septin 4 (SEPT4) Antigen-Profil

Protein Überblick

This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct\; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Genbezeichner und Symbole assoziert mit anti-Septin 4 (SEPT4) Antikörper

  • septin 4 (Sept4) Antikörper
  • septin 4 (SEPT4) Antikörper
  • septin 4 (PAAG_00317) Antikörper
  • septin 4 (PGTG_11810) Antikörper
  • uncharacterized protein C17orf47 homolog (LOC100012173) Antikörper
  • ARTS Antikörper
  • Bh5 Antikörper
  • BRADEION Antikörper
  • CE5B3 Antikörper
  • DKFZp459F1329 Antikörper
  • DKFZp459I029 Antikörper
  • EG3-1RVC Antikörper
  • EG3RVC Antikörper
  • Gm11492 Antikörper
  • H5 Antikörper
  • hCDCREL-2 Antikörper
  • MART Antikörper
  • OTTMUSG00000001265 Antikörper
  • PNUTL2 Antikörper
  • RP23-168C20.1 Antikörper
  • SEP4 Antikörper
  • SEPT4 Antikörper

Bezeichner auf Proteinebene für anti-Septin 4 (SEPT4) Antikörper

expression gene 3 in rat visual cortex , expression gene 3-1 in rat visual cortex , peanut-like 2 , septin-4 , septin 4 , CE5B3 beta , apoptosis-related protein in the TGF-beta signaling pathway , bradeion beta , brain protein H5 , cell division control-related protein 2 , cerebral protein 7 , peanut-like protein 2 , septin-M , M-Septin , cell division control-related protein 2b , peanut-like 2 homolog , septin H5

GENE ID SPEZIES
287606 Rattus norvegicus
455160 Pan troglodytes
9100863 Paracoccidioides sp. 'lutzii' Pb01
10544005 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100012173 Monodelphis domestica
100173213 Pongo abelii
100354312 Oryctolagus cuniculus
5414 Homo sapiens
18952 Mus musculus
480571 Canis lupus familiaris
538801 Bos taurus
Ausgewählte Anbieter für anti-Septin 4 (SEPT4) Antikörper
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