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The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development.
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Cow (Bovine) Polyclonal SEMA3B Primary Antibody für ICC, IF - ABIN250634
Fonseca, Bingle, Santos-Silva, Lopes, de Almeida, de Andrade, Mariano, Kowalski, Rangel, Martins, Meurer, Speight, Vargas: Semaphorins and neuropilins expression in salivary gland tumors. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016
data provide new insights into the role of SEMA3B in mammary gland and provides a new branch of GATA3 (zeige GATA3 Antikörper) signaling that is pivotal for inhibition of breast cancer progression and metastasis
By upregulating p53 (zeige TP53 Antikörper) and p21 (zeige CDKN1A Antikörper) expression and inhibiting Akt (zeige AKT1 Antikörper) (Ser473) phosphorylation, SEMA3B could induce cell cycle arrest at G1/S phase.
As the clinical pathological glioma grade increased, SEMA3B expression decreased.
Maternal SEMA 3B level increased in preeclampsia before the onset of manifestations, indicating that SEMA 3B plays a role in the pathogenesis of preeclampsia
Aberrant expression and methylation of SEMA3B could be suggested as markers of lung and renal cancer progression.
although plexin-A4 (zeige PLXNA4 Antikörper) overexpression restored Sema3A (zeige SEMA3A Antikörper) signaling in plexin-A1 (zeige PLXNA1 Antikörper)-silenced cells, it failed to restore Sema3B signaling in plexin-A2 (zeige Plxna2 Antikörper)-silenced cells.
SEMA3B mRNA and protein is not altered in severe early onset preeclamptic placentas.
CpG methylation of SEMA3B epigenetically regulates SEMA3B expression during development of gastric cancer.
The transcriptional activity of RHOA (zeige RHOA Antikörper), SEMA3B, and CKAP2 (zeige CKAP2 Antikörper) genes was assessed in blood samples of leukaemia patients and healthy donors.
Three candidate tumor-suppressor genes, SEMA3B, AXUD1 (zeige CSRNP1 Antikörper) and GNAT1 (zeige GNAT1 Antikörper) may be involved in oral squamous cell carcinoma.
Semaphorin3B may contribute to impaired bone formation by elevated TNF-alpha (zeige TNF Antikörper) in estrogen-deficiency-induced osteoporosis.
Dual functional activity of semaphorin 3B is required for positioning the anterior commissure.
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
, semaphorin 3B
, sema A(V)
, sema V
, semaphorin A
, sema A