anti-Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Antikörper

SGCG encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. Zusätzlich bieten wir Ihnen Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SGCG 6445 Q13326
SGCG 24053 P82348
SGCG 305941  
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Top anti-Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert WB SGCG Antibody (Center) (ABIN1881799) western blot analysis in MCF-7,MDA-MB231,MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the SGCG antibody detected the SGCG protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Hund Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$343.75
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of HeLa and MCF7 cells, using SGCG antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert WB SGCG antibody used at 1.25 ug/ml to detect target protein. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$388.93
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: gamma Sarcoglycan Antibody [NBP1-90299] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY424852) Immunohistochemistry-Paraffin: gamma Sarcoglycan Antibody [NBP1-90299] - Staining of human heart muscle shows strong membranous positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 16 Days
$460.63
Details
Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$317.63
Details
Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details

SGCG Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Antikörper

  1. Human Polyclonal SGCG Primary Antibody für WB - ABIN1881799 : McNally, Passos-Bueno, Bönnemann, Vainzof, de Sá Moreira, Lidov, Othmane, Denton, Vance, Zatz, Kunkel: Mild and severe muscular dystrophy caused by a single gamma-sarcoglycan mutation. in American journal of human genetics 1996 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal SGCG Primary Antibody für ELISA - ABIN4273377 : Rafii, Hagiwara, Mercado, Seo, Xu, Dugan, Owens, Hook, McQuillan, Young, Fallon: Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development. in Journal of cellular physiology 2006 (PubMed)

Weitere Antikörper gegen Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Interaktionspartner

Human Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaktionspartner

  1. This study showed that fifteen families were shown to carry SGCG variants in patient with early onset severe muscular dystrophy.

  2. FADH2-dependent monooxygenase (SgcE6 and SgcC) that catalyzes the hydroxylation of a PCP (zeige PRCP Antikörper)-tethered substrate

  3. These results position archvillin (zeige SVIL Antikörper) as a mechanically sensitive component of the dystrophin (zeige DMD Antikörper) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  4. A report of two siblings with severe childhood onset limb-girdle muscular dystrophy type 2C supports the theory that the mutation G787A in the SGCG gene is a founder mutation.

  5. Molecular epidemiologic methods were used to calculate the frequency of heterozygotes for this SGCG mutation in Moroccan newborns and to estimate the prevalence of LGMD2C in the Moroccan population.

  6. Data suggest that an SNP in an intron of SGCG (rs9552911) is associated with type 2 diabetes [Genome-Wide Association Study in Sikh populations in India & Meta-Analysis]

  7. The C allele of the c.-94C>G polymorphism in delta-sarcoglycan (zeige SGCD Antikörper) is a risk factor for HCM, which is increased by the Amerindian component and can play an important role in the etiology and progression of disease in Mexican patients

  8. four Greek Gypsy patients with limb girdle muscular dystrophy type 2C carried the same homozygous C283Y mutation in the gamma-sarcoglycan gene

  9. The relative incidence of LGMD2C among Japanese Duchenne muscular dystrophy (zeige DMD Antikörper)-like patients can be calculated as 1 in 161 patients suspected to have Duchenne muscular dystrophy (zeige DMD Antikörper).

  10. Clinical, histologic, and immunohistochemical characteristics of three children with limb-girdle muscular dystrophy type 2C. Two novel mutations in the gamma-sarcoglycan gene were present. We found phenotypic differences in two brothers.

Mouse (Murine) Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaktionspartner

  1. Cleavage of beta-DG still occurred when both MMP-2 (zeige MMP2 Antikörper) and MMP-9 (zeige MMP9 Antikörper) were knocked out in gamma - sarcoglycan-deficient mice. The study found that up-regulation of MMP-14 (zeige MMP14 Antikörper) is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy.

  2. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx (zeige DMD Antikörper) mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size.

  3. These results position archvillin (zeige SVIL Antikörper) as a mechanically sensitive component of the dystrophin (zeige DMD Antikörper) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  4. This study supports a model where dystrophin (zeige DMD Antikörper), but not the sarcoglycans, protects the cardiac myocyte against mechanical damage.

  5. localization of gamma-SG does not require Tyr (zeige TYR Antikörper)(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation

  6. The limb, shoulder, and pelvic muscles of the gsg-/- mice exhibited progressive muscle hypertrophy and weakness with age, and the findings were similar to those seen in other mouse models for limb-girdle and Duchenne muscular dystrophy (zeige DMD Antikörper).

  7. In sarcoglycan (zeige SGCD Antikörper) mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation.

  8. delta- and gamma-sarcoglycan prevent vascular spasm in coronary arteries and in vascular smooth muscle

  9. sarcoglycan (zeige SGCD Antikörper) and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction

  10. Sarcoglycan gamma missense mutations affect sarcoglycan (zeige SGCD Antikörper) complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan (zeige SGCD Antikörper) mutations in muscular dystrophies.

Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Antigen-Profil

Protein Überblick

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Genbezeichner und Symbole assoziert mit SGCG

  • sarcoglycan, gamma (sgcg) Antikörper
  • sarcoglycan gamma (SGCG) Antikörper
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) Antikörper
  • sarcoglycan gamma (Sgcg) Antikörper
  • sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg) Antikörper
  • sarcoglycan, gamma (Sgcg) Antikörper
  • 35DAG Antikörper
  • 35kDa Antikörper
  • 5430420E18Rik Antikörper
  • A4 Antikörper
  • AI642964 Antikörper
  • DAGA4 Antikörper
  • DMDA Antikörper
  • DMDA1 Antikörper
  • gamma-SG Antikörper
  • LGMD2C Antikörper
  • MAM Antikörper
  • SCARMD2 Antikörper
  • SCG3 Antikörper
  • TYPE Antikörper
  • zgc:100924 Antikörper

Bezeichner auf Proteinebene für SGCG

gamma-sarcoglycan , 35 kDa dystrophin-associated glycoprotein , 35DAG , 35kD dystrophin-associated glycoprotein , gamma sarcoglycan , gamma-SG , sgcg gene for gamma-sarcoglycan , sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)

GENE ID SPEZIES
445292 Danio rerio
6445 Homo sapiens
486043 Canis lupus familiaris
100272144 Sus scrofa
506155 Bos taurus
100009214 Oryctolagus cuniculus
101825067 Mesocricetus auratus
24053 Mus musculus
305941 Rattus norvegicus
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