Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteine (SGCG)

SGCG encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. Zusätzlich bieten wir Ihnen Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Antikörper (44) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SGCG 6445 Q13326
SGCG 24053 P82348
Ratte SGCG SGCG 305941  
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Top Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteine auf antikoerper-online.de

Showing 8 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,588.67
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,588.67
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Hefe Syrischer Goldhamster His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,588.67
Details

SGCG Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Mouse (Murine) ,
,

Weitere Proteine zu Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaktionspartnern

Human Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaktionspartner

  1. This study showed that fifteen families were shown to carry SGCG variants in patient with early onset severe muscular dystrophy.

  2. FADH2-dependent monooxygenase (SgcE6 and SgcC) that catalyzes the hydroxylation of a PCP (zeige PRCP Proteine)-tethered substrate

  3. These results position archvillin (zeige SVIL Proteine) as a mechanically sensitive component of the dystrophin (zeige DMD Proteine) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  4. A report of two siblings with severe childhood onset limb-girdle muscular dystrophy type 2C supports the theory that the mutation G787A in the SGCG gene is a founder mutation.

  5. Molecular epidemiologic methods were used to calculate the frequency of heterozygotes for this SGCG mutation in Moroccan newborns and to estimate the prevalence of LGMD2C in the Moroccan population.

  6. Data suggest that an SNP in an intron of SGCG (rs9552911) is associated with type 2 diabetes [Genome-Wide Association Study in Sikh populations in India & Meta-Analysis]

  7. The C allele of the c.-94C>G polymorphism in delta-sarcoglycan (zeige SGCD Proteine) is a risk factor for HCM, which is increased by the Amerindian component and can play an important role in the etiology and progression of disease in Mexican patients

  8. four Greek Gypsy patients with limb girdle muscular dystrophy type 2C carried the same homozygous C283Y mutation in the gamma-sarcoglycan gene

  9. The relative incidence of LGMD2C among Japanese Duchenne muscular dystrophy (zeige DMD Proteine)-like patients can be calculated as 1 in 161 patients suspected to have Duchenne muscular dystrophy (zeige DMD Proteine).

  10. Clinical, histologic, and immunohistochemical characteristics of three children with limb-girdle muscular dystrophy type 2C. Two novel mutations in the gamma-sarcoglycan gene were present. We found phenotypic differences in two brothers.

Mouse (Murine) Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaktionspartner

  1. Cleavage of beta-DG still occurred when both MMP-2 (zeige MMP2 Proteine) and MMP-9 (zeige MMP9 Proteine) were knocked out in gamma - sarcoglycan-deficient mice. The study found that up-regulation of MMP-14 (zeige MMP14 Proteine) is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy.

  2. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx (zeige DMD Proteine) mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size.

  3. These results position archvillin (zeige SVIL Proteine) as a mechanically sensitive component of the dystrophin (zeige DMD Proteine) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  4. This study supports a model where dystrophin (zeige DMD Proteine), but not the sarcoglycans, protects the cardiac myocyte against mechanical damage.

  5. localization of gamma-SG does not require Tyr (zeige TYR Proteine)(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation

  6. The limb, shoulder, and pelvic muscles of the gsg-/- mice exhibited progressive muscle hypertrophy and weakness with age, and the findings were similar to those seen in other mouse models for limb-girdle and Duchenne muscular dystrophy (zeige DMD Proteine).

  7. In sarcoglycan (zeige SGCD Proteine) mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation.

  8. delta- and gamma-sarcoglycan prevent vascular spasm in coronary arteries and in vascular smooth muscle

  9. sarcoglycan (zeige SGCD Proteine) and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction

  10. Sarcoglycan gamma missense mutations affect sarcoglycan (zeige SGCD Proteine) complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan (zeige SGCD Proteine) mutations in muscular dystrophies.

Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Protein Überblick

Protein Überblick

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Genbezeichner und Symbole assoziert mit SGCG

  • sarcoglycan, gamma (sgcg)
  • sarcoglycan gamma (SGCG)
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG)
  • sarcoglycan gamma (Sgcg)
  • sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg)
  • sarcoglycan, gamma (Sgcg)
  • 35DAG Protein
  • 35kDa Protein
  • 5430420E18Rik Protein
  • A4 Protein
  • AI642964 Protein
  • DAGA4 Protein
  • DMDA Protein
  • DMDA1 Protein
  • gamma-SG Protein
  • LGMD2C Protein
  • MAM Protein
  • SCARMD2 Protein
  • SCG3 Protein
  • TYPE Protein
  • zgc:100924 Protein

Bezeichner auf Proteinebene für SGCG

gamma-sarcoglycan , 35 kDa dystrophin-associated glycoprotein , 35DAG , 35kD dystrophin-associated glycoprotein , gamma sarcoglycan , gamma-SG , sgcg gene for gamma-sarcoglycan , sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)

GENE ID SPEZIES
445292 Danio rerio
6445 Homo sapiens
486043 Canis lupus familiaris
100272144 Sus scrofa
506155 Bos taurus
100009214 Oryctolagus cuniculus
101825067 Mesocricetus auratus
24053 Mus musculus
305941 Rattus norvegicus
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