Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Zusätzlich bieten wir Ihnen SAE1 Antikörper (133) und SAE1 Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.
Showing 5 out of 10 products:
the expression of SENP8 (zeige SENP8 ELISA Kits), SAE1, PIAS1 (zeige PIAS1 ELISA Kits), PIAS2 and ZMIZ1 is deregulated in the majority of PTC (zeige F9 ELISA Kits) tissues, likely contributing to the PTC (zeige F9 ELISA Kits) phenotype.
as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells.
Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 antibody as marker of dermatomyositis.
Data show that the SAE2 subunit of the small ubiquitin-like modifier (SUMO (zeige SUMO1 ELISA Kits)) E1 is autoSUMOylated at residue Lys (zeige LYZ ELISA Kits)-236, and SUMOylation was catalyzed by Ubc9 (zeige UBE2I ELISA Kits) at several additional Lys (zeige LYZ ELISA Kits) residues surrounding the catalytic Cys (zeige DNAJC5 ELISA Kits)-173 of SAE2.
loss of SAE1/2 activity drives synthetic lethality with Myc (zeige MYC ELISA Kits); inactivation of SAE2 leads to mitotic catastrophe and cell death upon Myc (zeige MYC ELISA Kits) hyperactivation; findings in Myc (zeige MYC ELISA Kits)-high breast cancers suggest low tumor SAE1 and SAE2 correlates metastasis-free survival
The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 and in Uba2, and demonstrate that their import is mediated by importin alpha/beta in vitro and in intact cells.
structures of heterodimeric Sae1/Sae2-Mg.ATP and Sae1/Sae2-SUMO-1 (zeige SUMO1 ELISA Kits)-Mg.ATP complexes
SUMO-1 controls the protein stability and the biological function of phosducin.
sae1 is essential for the maintenance of hematopoietic stem/progenitor cells during fetal hematopoiesis in zebrafish.
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999
SUMO-1 activating enzyme E1 N subunit
, SUMO-1 activating enzyme subunit 1
, SUMO-activating enzyme subunit 1
, activator of SUMO1
, sentrin/SUMO-activating protein AOS1
, ubiquitin-like 1-activating enzyme E1A
, ubiquitin-like protein SUMO-1 activating enzyme
, ubiquitin-like (sentrin) activating enzyme E1A
, ubiquitin-like 1 (sentrin) activating enzyme E1A
, ubiquitin-like 1 (sentrin) activating enzyme subunit 1
, SUMO-activating enzyme E1 N subunit
, SUMO1 activating enzyme subunit 2a
, Ubiquitin-like 1-activating enzyme E1A